SNAG Loop DSI results

Overview

This is the analysis of white matter dsi studio connectometry for Maze and Loop

Methods

Participants

• Total number of scans = 120 (males and females)

• Total scans used in analysis= 118
  

• Excluded subs 329 and 372 from analyses due to bad behavior data and Subject 347 failed quality control check in DSI

• Several subjects removed because they did not have rad3 score
  
  

Loop: Position Error, Degree Error, Angular Error

• Rad 3
  • All subjects: 38
  • Men: 14
  • Women: 24
  • Stage:
    • Pre: 10
    • Peri: 7
    • Post: 7
• Average
  • All subjects: 42
  • Men: 17
  • Women: 25
  • Stage:
    • Pre: 11
    • Peri: 7
    • Post: 7

Scan parameters

• Locations from UCSB and UCI
  

QSIprep

• Version used: 0.16.0RC3

• The following parameters were used

  • dwi_denoise_window 5
  • hmc_model 3dSHORE
  • hmc-transform Rigid
  • shoreline_iters 2
    DSI Studio

• Version and tags used via singularity container: chen-2022-07-31

• Parameters

  • T-threshold = 2.5
  • Length = 25
  • Permutation = 4,000
  • pruning 4
  • non normalized QA

Connectronomy analysis methods write up
A diffusion spectrum imaging scheme was used, and a total of 128 diffusion sampling were acquired.The maximum b-value was 4990 s/mm². The in-plane resolution was 1.8 mm. The slice thickness was 1.8 mm. The accuracy of b-table orientation was examined by comparing fiber orientations with those of a population-averaged template (Yeh et al. Neuroimage, 2018). The b-table was flipped by. The diffusion data were reconstructed in the MNI space using q-space diffeomorphic reconstruction (Yeh et al., Neuroimage, 58(1):91-9, 2011) to obtain the spin distribution function (Yeh et al., IEEE TMI, ;29(9):1626-35, 2010). A diffusion sampling length ratio of 1.25 was used. The output resolution in diffeomorphic reconstruction was 1.8 mm isotropic. The tensor metrics were calculated using DWI with b-value lower than 1750 s/mm². The quantitative anisotropy was extracted as the local connectome fingerprint (LCF, Yeh et al. PLoS Comput Biol 12(11): e1005203) and used in the connectometry analysis.

Diffusion MRI connectometry (Yeh et al. NeuroImage 125 (2016): 162-171) was used to derive the correlational tractography that has QA, MD, AD, and RD correlated with Maze Accuracy and Loop variables. A nonparametric Spearman partial correlation was used to derive the correlation, and the effect of sex, age_scan_years, and repo_status was removed using a multiple regression model. The total number of subjects varied on analysis (See Analyses and Final sample sizes above). A T-score threshold of 2.5 was assigned and tracked using a deterministic fiber tracking algorithm (Yeh et al. PLoS ONE 8(11): e80713, 2013) to obtain correlational tractography. A seeding region was placed at whole brain (39,49,29) .

The tracks were filtered by topology-informed pruning (Yeh et al. Neurotherapeutics, 16(1), 52-58, 2019) with 4 iteration(s). A length threshold of 25 voxel distance was used to select tracks. To estimate the false discovery rate, a total of 4000 randomized permutations were applied to the group label to obtain the null distribution of the track length.

Behavior

Angular error is the degree difference btween the start location and the end location. Participants were tested on three different sizes of circles: Radius 1m, 2m, and 3m. For white matter analysis we used the data from radius 3 and an average of performance on all three circle sizes. The average position error on the 1m circle is 47.6146335. The average position error on the 2m circle is 56.1275526. The average position error on the 3m circle is 68.3846003. The average position error across all sizes is 56.4495802.

There are were significant differences in performance between men and women on the rad3 loop (t test, p= 0.50858) and on the average of all circles ( p = 0.4163938). The mean distance for degrees traveled in men on the rad3 circle was 64.924295, and in women it was 70.4031117. Men undershot the target location while women overshot the location The mean for the average of all circles in men is 51.2907976 and women is 59.9575524.

The average for degrees traveled on rad3
pre = 71.073026

peri = 73.2993367

post = 71.0431529

The average for degrees traveled on average of all circles
pre = 62.239975

peri = 63.5120417

post = 55.5092757

Results

Loop angular error Rad3

QA

All subjects

Positive Correlations (FDR = 0.000675)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	877	55.9796	12.0679	6403
Cerebellum_L	64	53.1643	4.58556	878
Fornix_R	12	52.1689	2.5954	276
Cingulum_Frontal_Parietal_L	10	52.4089	1.953	157

Negative Correlations (FDR = 0.004296)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corticospinal_Tract_R	304	55.1267	8.55124	3166
Arcuate_Fasciculus_R	182	52.5773	5.35013	1182
Medial_Lemniscus_R	52	56.3921	4.97225	1095
Corpus_Callosum_Tapetum	23	52.788	3.23916	435

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3

Men

Positive Correlations (FDR = 0.012481)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	994	58.7371	13.4206	8309
Cerebellum_L	631	56.935	10.6459	5068
Cerebellum_R	249	53.6912	9.48158	3791
Corticospinal_Tract_R	238	59.1276	7.75247	2791
Corpus_Callosum_Tapetum	170	59.6702	9.6741	4386
Arcuate_Fasciculus_L	159	55.8202	7.70542	2603
Inferior_Fronto_Occipital_Fasciculus_R	156	57.063	6.75498	2045
Corpus_Callosum_Body	154	59.7992	9.43738	4183
Superior_Longitudinal_Fasciculus2_R	129	56.3811	7.73299	2648
Arcuate_Fasciculus_R	116	57.8156	7.73957	2720
Superior_Longitudinal_Fasciculus3_R	96	60.4046	6.44723	1972
Medial_Lemniscus_R	90	56.6319	6.76737	2037
Corticostriatal_Tract_Superior_R	69	55.5161	5.76474	1449
Vermis	63	53.215	5.77937	1396
Corpus_Callosum_Forceps_Major	59	62.0339	6.02566	1769
Cingulum_Frontal_Parietal_L	53	61.7079	3.18616	492
Inferior_Longitudinal_Fasciculus_R	51	54.9511	5.04392	1098
Corticopontine_Tract_Parietal_R	50	60.2026	5.63052	1499
Thalamic_Radiation_Posterior_L	47	54.3075	5.31519	1205
Middle_Cerebellar_Peduncle	47	67.1561	4.36728	1006
Corticopontine_Tract_Parietal_L	39	57.7474	5.65617	1451
Corticostriatal_Tract_Posterior_L	38	65.009	5.66576	1639
Thalamic_Radiation_Anterior_R	34	57.6071	3.81935	660
Corticostriatal_Tract_Posterior_R	33	55.2883	5.01246	1091
Inferior_Fronto_Occipital_Fasciculus_L	18	55.2274	3.66302	582
Parietal_Aslant_Tract_L	18	61.678	2.37395	273
Cingulum_Frontal_Parahippocampal_L	15	57.4842	2.63722	314
Cingulum_Parolfactory_L	13	65.2353	2.72336	380
Extreme_Capsule_R	13	53.9993	3.22829	442
Frontal_Aslant_Tract_R	13	54.6191	3.28883	464
Dentatorubrothalamic_Tract_R	13	52.9296	2.95094	362

Negative Correlations (FDR = 0.024096)

.
Cerebellum_L
116
55.5436
7.63954
2546

Figures

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in men

Women

Positive Correlations (FDR = 0.015385)

.
Cerebellum_L
35
54.407
3.71266
589

Negative Correlations (FDR = 0.001027)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corticospinal_Tract_R	239	55.4744	7.1526	2229
Arcuate_Fasciculus_R	114	54.341	4.77717	974
Medial_Lemniscus_R	95	57.0645	4.7495	1011
Corpus_Callosum_Tapetum	60	54.4736	4.43891	843
Inferior_Longitudinal_Fasciculus_R	25	57.4453	3.14057	445
Corticostriatal_Tract_Superior_R	20	53.9077	3.42961	498
Cingulum_Frontal_Parietal_L	16	53.6303	2.50826	265
Dentatorubrothalamic_Tract_R	15	51.746	3.22617	423

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in women

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in women

pre

Positive Correlations (FDR = 0.036981)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Major	532	62.1823	10.7882	5684
Corpus_Callosum_Tapetum	438	55.1425	11.7919	6022
Corpus_Callosum_Body	346	59.1443	9.77555	4439
Cerebellum_L	155	55.1539	7.57713	2487
Corpus_Callosum_Forceps_Minor	134	57.2479	7.07245	2249
Fornix_L	60	61.0718	4.38192	921
Fornix_R	57	56.4362	3.77901	633
Arcuate_Fasciculus_L	50	54.402	3.53524	534
Inferior_Longitudinal_Fasciculus_L	27	56.5924	5.23694	1219
Thalamic_Radiation_Posterior_L	24	53.8504	4.31094	786
Corticostriatal_Tract_Posterior_L	20	54.8058	3.57456	550
Cingulum_Frontal_Parietal_R	14	62.1548	2.87679	404

Negative Correlations (FDR = 0.009185)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Inferior_Fronto_Occipital_Fasciculus_R	510	63.0641	9.04814	4055
Corticospinal_Tract_L	271	57.1097	11.0875	5514
Inferior_Fronto_Occipital_Fasciculus_L	262	56.5833	7.10437	2243
Corticospinal_Tract_R	251	58.6942	8.60702	3415
Cerebellum_L	222	56.1792	7.86447	2729
Cingulum_Frontal_Parietal_L	204	55.5582	6.13807	1644
Middle_Cerebellar_Peduncle	174	55.7707	8.49636	3162
Corpus_Callosum_Tapetum	162	60.7	7.25022	2506
Inferior_Longitudinal_Fasciculus_R	148	58.2545	5.78277	1530
Arcuate_Fasciculus_L	117	58.4216	7.03056	2268
Medial_Lemniscus_L	114	57.2181	7.15872	2303
Corticostriatal_Tract_Superior_L	107	56.5335	8.3584	3102
Medial_Lemniscus_R	80	55.1851	6.23326	1684
Dentatorubrothalamic_Tract_L	70	55.1835	7.00213	2125
Cingulum_Parolfactory_R	69	59.4306	3.99242	744
Arcuate_Fasciculus_R	64	60.978	6.21183	1848
Superior_Longitudinal_Fasciculus2_R	64	56.7607	5.33534	1269
Cingulum_Frontal_Parietal_R	62	55.4943	5.40012	1271
Corpus_Callosum_Body	53	54.5364	5.5849	1336
Uncinate_Fasciculus_R	51	56.2061	4.06932	731
Vermis	50	53.4535	4.85852	991
Corticopontine_Tract_Parietal_L	49	65.4395	4.3711	982
Superior_Longitudinal_Fasciculus2_L	40	55.5082	5.31812	1233
Cingulum_Frontal_Parahippocampal_L	36	53.5589	3.89753	639
Dentatorubrothalamic_Tract_R	36	55.5621	5.1089	1139
Extreme_Capsule_L	18	59.1259	3.47884	562
Cingulum_Frontal_Parahippocampal_R	15	56.408	2.66649	315
Corticopontine_Tract_Parietal_R	13	60.3215	3.60294	615
Extreme_Capsule_R	12	53.1778	2.41705	244
Corpus_Callosum_Forceps_Major	12	62.6695	2.78586	382
Superior_Longitudinal_Fasciculus3_L	10	53.0228	2.9928	373
Corticostriatal_Tract_Posterior_R	10	54.2202	3.2795	458

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in pre menopausal women

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in pre menopausal women

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in pre menopausal women

peri

Positive Correlations (FDR = 0.317868)
No Significant Findings

Negative Correlations (FDR = 0.029057)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Body	330	65.9288	14.8677	11446
Corticospinal_Tract_R	247	65.1614	10.797	5966
Inferior_Fronto_Occipital_Fasciculus_R	237	62.9996	11.1414	6142
Corpus_Callosum_Tapetum	230	64.0876	12.4875	7849
Cerebellum_L	226	55.824	13.6766	8201
Superior_Longitudinal_Fasciculus2_R	222	63.6687	11.0012	6052
Arcuate_Fasciculus_R	217	68.5276	10.5223	5959
Middle_Cerebellar_Peduncle	194	61.8863	11.7635	6726
Corpus_Callosum_Forceps_Major	165	60.5409	10.4133	5156
Cingulum_Frontal_Parietal_R	164	67.6788	8.10524	3492
Corticostriatal_Tract_Posterior_R	164	65.9497	10.4386	5644
Arcuate_Fasciculus_L	156	58.5221	10.6119	5176
Dentatorubrothalamic_Tract_R	132	60.3919	10.8337	5567
Medial_Lemniscus_R	117	64.7779	8.32734	3528
Cerebellum_R	112	54.0119	11.2533	5372
Inferior_Fronto_Occipital_Fasciculus_L	107	63.858	8.71128	3806
Inferior_Longitudinal_Fasciculus_L	103	61.2768	8.57526	3539
Inferior_Longitudinal_Fasciculus_R	99	60.4508	9.74312	4507
Corticostriatal_Tract_Posterior_L	83	60.9943	8.90054	3795
Corticospinal_Tract_L	82	62.5653	7.91577	3079
Frontal_Aslant_Tract_L	80	61.3321	8.23794	3269
Corticopontine_Tract_Parietal_R	80	62.2362	7.68523	2887
Superior_Longitudinal_Fasciculus2_L	78	60.0313	8.49067	3399
Dentatorubrothalamic_Tract_L	77	58.3208	8.58	3372
Corticostriatal_Tract_Superior_L	65	57.147	8.1058	2949
Thalamic_Radiation_Posterior_R	63	60.3866	7.08243	2379
Thalamic_Radiation_Anterior_R	62	66.3354	6.61821	2282
Cingulum_Frontal_Parietal_L	58	60.6987	6.36768	1933
Corticostriatal_Tract_Superior_R	58	62.875	7.70151	2929
Corpus_Callosum_Forceps_Minor	58	61.6993	7.08284	2431
Medial_Lemniscus_L	56	58.516	6.31193	1831
Vermis	56	56.2245	6.62987	1941
Thalamic_Radiation_Superior_R	50	64.7278	7.14598	2596
Superior_Longitudinal_Fasciculus1_R	49	65.5205	5.81321	1739
Anterior_Commissure	45	65.2566	6.16506	1948
Extreme_Capsule_R	42	62.6303	5.72815	1614
Cingulum_Parahippocampal_Parietal_R	40	56.8632	5.66649	1434
Corticopontine_Tract_Parietal_L	38	65.4282	6.00172	1851
Reticular_Tract_R	36	62.3961	6.4393	2032
Superior_Longitudinal_Fasciculus3_R	31	60.652	5.2899	1333
Parietal_Aslant_Tract_L	29	58.9126	4.83128	1080
Corticopontine_Tract_Frontal_R	29	58.1488	5.48102	1372
Cingulum_Parolfactory_R	25	66.169	4.14528	893
Middle_Longitudinal_Fasciculus_R	23	58.529	5.07082	1182
Thalamic_Radiation_Posterior_L	22	58.7316	5.03631	1170
Extreme_Capsule_L	20	63.405	4.68279	1092
Optic_Radiation_L	17	55.7674	3.51125	540
Superior_Longitudinal_Fasciculus3_L	16	59.756	4.44671	928
Corticopontine_Tract_Occipital_R	16	64.6266	3.27979	546
Reticular_Tract_L	16	64.0179	4.49301	1015
Frontal_Aslant_Tract_R	13	53.6847	4.01	678
Parietal_Aslant_Tract_R	13	57.8639	3.78188	650
Corticopontine_Tract_Frontal_L	12	67.5064	3.65684	709
Cingulum_Parolfactory_L	11	60.1934	2.12261	213
Thalamic_Radiation_Superior_L	11	62.7421	3.76899	700
Cingulum_Frontal_Parahippocampal_R	10	68.0192	3.07153	504
Middle_Longitudinal_Fasciculus_L	10	56.2141	3.62761	581

Figures

Glass Brain displaying tracts that had QA negatively correlated with loop angular error rad3 in peri menopausal women

post

Positive Correlations (FDR = 1.000000)
No Significant Findings

Negative Correlations (FDR = 0.302332)
No Significant Findings

Peri + Post

Positive Correlations (FDR = 0.082506)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	681	58.7354	11.7131	6329
Corpus_Callosum_Body	366	56.2798	12.6399	7062
Middle_Cerebellar_Peduncle	306	59.0543	10.7821	5392
Corpus_Callosum_Forceps_Major	173	61.4656	7.70776	2868
Corpus_Callosum_Tapetum	157	54.9597	8.07268	2813
Inferior_Fronto_Occipital_Fasciculus_R	83	55.7638	6.1006	1630
Uncinate_Fasciculus_R	55	57.9419	4.89184	1089
Cingulum_Frontal_Parietal_L	47	56.1396	3.59549	570
Cerebellum_L	42	53.2038	3.941	649
Cingulum_Frontal_Parietal_R	40	58.206	4.37497	875
Cingulum_Parolfactory_L	32	53.8777	2.88008	351
Cingulum_Parolfactory_R	29	57.8008	2.84716	368
Inferior_Longitudinal_Fasciculus_R	14	52.2868	2.95257	358
Thalamic_Radiation_Anterior_R	13	55.0804	3.24311	455

Negative Correlations (FDR = 0.081279)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	920	66.7952	14.7981	11488
Corpus_Callosum_Body	803	65.7615	16.6946	14395
Corpus_Callosum_Forceps_Major	538	70.7981	12.2352	8324
Cerebellum_R	495	56.2048	13.646	8220
Corpus_Callosum_Tapetum	404	63.2638	12.3203	7542
Corticospinal_Tract_R	392	62.4423	8.81294	3809
Arcuate_Fasciculus_L	222	56.3231	9.9914	4416
Inferior_Fronto_Occipital_Fasciculus_L	207	62.323	8.92155	3896
Medial_Lemniscus_R	167	57.1932	8.1491	2983
Inferior_Longitudinal_Fasciculus_L	149	62.3197	7.67076	2880
Corticostriatal_Tract_Superior_R	98	55.2739	6.75859	1983
Corticostriatal_Tract_Posterior_L	83	63.6939	8.10229	3284
Thalamic_Radiation_Posterior_R	79	59.1474	6.56477	2002
Cerebellum_L	75	54.2486	7.18739	2201
Corticospinal_Tract_L	74	59.3102	6.48496	1959
Superior_Longitudinal_Fasciculus2_R	73	57.1082	5.34	1279
Thalamic_Radiation_Posterior_L	67	57.5649	6.86221	2129
Corticostriatal_Tract_Posterior_R	64	58.229	6.87087	2159
Cingulum_Frontal_Parietal_L	62	61.1051	5.84037	1637
Middle_Longitudinal_Fasciculus_R	62	54.7522	6.35008	1734
Cingulum_Frontal_Parietal_R	58	57.013	5.1378	1182
Inferior_Fronto_Occipital_Fasciculus_R	54	55.2686	6.21744	1678
Corticostriatal_Tract_Superior_L	50	53.9601	5.27443	1179
Extreme_Capsule_L	49	59.56	5.9696	1667
Arcuate_Fasciculus_R	40	56.4534	5.1632	1182
Extreme_Capsule_R	40	56.0137	4.54058	907
Corticopontine_Tract_Parietal_R	34	58.8266	5.97962	1652
Middle_Longitudinal_Fasciculus_L	33	56.3185	4.13692	757
Cingulum_Parolfactory_L	31	58.2019	4.34502	863
Medial_Lemniscus_L	30	56.7371	4.62938	955
Dentatorubrothalamic_Tract_R	28	53.5793	5.02364	1062
Corticopontine_Tract_Parietal_L	24	59.4321	5.07032	1200
Thalamic_Radiation_Anterior_R	24	59.1752	4.15147	801
Superior_Longitudinal_Fasciculus1_L	19	56.8632	3.08122	424
Corticostriatal_Tract_Anterior_L	19	54.2121	3.74137	596
Dentatorubrothalamic_Tract_L	19	53.5778	4.12783	717
Cingulum_Parolfactory_R	18	57.7912	2.75298	344
Thalamic_Radiation_Anterior_L	18	55.1118	3.74787	608
Thalamic_Radiation_Superior_R	17	55.1917	3.63259	572
Cingulum_Frontal_Parahippocampal_R	15	58.8151	3.4159	539
Corticopontine_Tract_Occipital_L	11	58.3899	2.53628	295
Corticostriatal_Tract_Anterior_R	11	54.1962	3.5353	532
Anterior_Commissure	11	51.8178	3.15069	404
Corticopontine_Tract_Occipital_R	10	56.62	2.73237	332

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in peri and post menopausal women

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in peri and post menopausal women

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in peri and post menopausal women

Plots

## [1] "Corticospinal_Tract_R"

## [1] "Corpus_Callosum_Tapetum"

## [1] "Arcuate_Fasciculus_R"

## [1] "Medial_Lemniscus_R"

## [1] "Corticostriatal_Tract_Superior_R"

## [1] "Cingulum_Frontal_Parietal_L"

## [1] "Inferior_Longitudinal_Fasciculus_R"

## [1] "Dentatorubrothalamic_Tract_R"

MD

All subjects

Positive Correlations (FDR = 0.052632)

.
Fornix_L
14
54.0197
3.34248
474

Negative Correlations (FDR = 0.001083)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_R	385	56.2115	7.25851	2326
Fornix_L	359	55.8681	8.22718	2970
Thalamic_Radiation_Superior_L	21	54.4852	3.44885	509

Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop Angular error rad3

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 in peri and post menopausal women

Glass Brain displaying tracts that had MD positively and negatively correlated with loop angular error rad3 in peri and post menopausal women

Men

Positive Correlations (FDR = 0.052789)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	1565	58.822	9.85954	4491
Fornix_R	252	55.9948	7.25689	2316
Thalamic_Radiation_Superior_L	110	56.39	6.15898	1680
Thalamic_Radiation_Superior_R	11	57.0999	2.44914	269
Corpus_Callosum_Forceps_Major	10	53.2237	3.24436	440
Cerebellum_L	10	52.8089	2.50373	260

Negative Correlations (FDR = 1.000000) Not significant

Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop Angular error rad3 in men

Glass Brain displaying tracts that had MD positively correlated with loop angular error rad3 in peri and post menopausal women

Women

Positive Correlations (FDR = 1.000000) Not significant

Negative Correlations (FDR = 0.000594)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	790	55.9141	9.18768	3707
Fornix_R	298	55.11	6.73613	1964
Corpus_Callosum_Tapetum	112	60.6023	6.4171	1960
Corpus_Callosum_Body	106	57.9578	5.31933	1288
Thalamic_Radiation_Superior_L	78	53.3173	5.43288	1236
Optic_Radiation_L	29	54.8945	3.35399	485
Cingulum_Frontal_Parietal_L	11	54.5619	1.51225	98
Corpus_Callosum_Forceps_Major	10	53.6157	2.34722	232

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 women

Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in women

pre

Positive Correlations (FDR = 1.000000) Not significant

Negative Correlations (FDR = 0.027414)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	593	60.8483	8.51618	3466
Fornix_R	229	57.3531	5.34522	1287
Cerebellum_R	63	54.2347	4.15111	734
Thalamic_Radiation_Superior_L	36	53.8466	3.98621	672
Corpus_Callosum_Body	36	64.507	4.33708	953
Corpus_Callosum_Tapetum	36	59.8425	4.25515	851
Corpus_Callosum_Forceps_Major	31	55.6306	4.18162	764
Cingulum_Frontal_Parietal_L	17	55.0485	1.72734	129

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 pre menopausal women

Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in pre menopausal women

peri

Positive Correlations (FDR = 1.000000) Not significant

Negative Correlations (FDR = 0.018769)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Tapetum	136	61.3216	9.20066	4077
Corpus_Callosum_Forceps_Major	125	61.5881	10.2136	5046
Cerebellum_R	96	54.6717	8.23653	2913
Corpus_Callosum_Body	94	63.0077	8.48647	3564
Fornix_L	89	62.0309	6.68314	2176
Corticostriatal_Tract_Posterior_R	71	56.0654	7.4759	2461
Inferior_Longitudinal_Fasciculus_R	63	62.7407	7.7058	2926
Corpus_Callosum_Forceps_Minor	47	59.0682	6.8029	2147
Cerebellum_L	44	53.5571	6.30093	1670
Arcuate_Fasciculus_R	30	58.1423	5.17726	1224
Inferior_Fronto_Occipital_Fasciculus_L	26	60.3186	5.16947	1266
Inferior_Fronto_Occipital_Fasciculus_R	25	57.9908	4.96774	1124
Arcuate_Fasciculus_L	23	55.6588	4.4714	874
Thalamic_Radiation_Superior_L	23	58.2649	3.96659	720
Fornix_R	23	61.9287	3.69203	663
Dentatorubrothalamic_Tract_L	21	55.6267	4.9396	1066
Middle_Cerebellar_Peduncle	21	63.6313	4.1507	861
Inferior_Longitudinal_Fasciculus_L	19	59.3809	4.15976	807
Dentatorubrothalamic_Tract_R	16	58.7448	3.74475	647
Optic_Radiation_L	14	55.7199	3.83613	644
Anterior_Commissure	14	57.5897	3.66635	608
Corticostriatal_Tract_Posterior_L	13	57.4001	3.65424	602
Thalamic_Radiation_Posterior_R	11	54.8985	3.79813	622
Reticular_Tract_L	11	64.9192	2.82183	406
Cingulum_Frontal_Parietal_L	10	61.3974	2.95475	421
Superior_Longitudinal_Fasciculus2_L	10	59.0103	3.38803	532
Corticospinal_Tract_L	10	53.4043	3.26818	448

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 peri menopausal women

Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in peri menopausal women

post

Positive Correlations (FDR = 1.000000)

No Significant Findings

Negative Correlations (FDR = 0.289057)

No Significant Findings

Peri + Post

Positive Correlations (FDR = 1.000000)

No Significant Findings

Negative Correlations (FDR = 0.187319)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	923	57.9248	10.231	4762
Corpus_Callosum_Tapetum	860	60.3349	12.8388	7811
Fornix_R	305	56.5731	7.42714	2451
Cerebellum_R	143	53.405	7.3744	2281
Corpus_Callosum_Body	124	59.1681	7.52153	2629
Thalamic_Radiation_Superior_L	115	58.4374	6.05373	1682
Corpus_Callosum_Forceps_Major	114	58.4289	7.64203	2680
Inferior_Longitudinal_Fasciculus_R	45	56.8591	5.2503	1231
Inferior_Fronto_Occipital_Fasciculus_L	31	54.8414	4.20885	763
Corticostriatal_Tract_Posterior_R	23	54.7086	4.0073	690
Inferior_Longitudinal_Fasciculus_L	20	53.5151	3.94463	654
Cingulum_Frontal_Parietal_L	16	55.1192	2.81892	344
Cingulum_Frontal_Parahippocampal_L	15	62.6689	3.68674	669
Middle_Cerebellar_Peduncle	15	53.2047	2.78883	325
Arcuate_Fasciculus_L	13	56.4665	2.93872	383
Optic_Radiation_L	10	54.6088	2.7485	324

Figures

Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in peri and post menopausal women

Plots

## [1] "Fornix_L"

## [1] "Fornix_R"

## [1] "Thalamic_Radiation_Superior_L"

## [1] "Corpus_Callosum_Forceps_Major"

AD

All subjects

Positive Correlations (FDR = 0.083333)

V1	V2	V3
Tract Name	Fornix_L	NA
number of tracts	8	NA
mean length(mm)	51.5	NA
span(mm)	19.5723	NA
curl	2.63126	NA
elongation	19.8232	NA
diameter(mm)	2.59796	NA
volume(mm^3)	273	NA
trunk volume(mm^3)	118	NA
branch volume(mm^3)	155	NA
total surface area(mm^2)	1390	NA
total radius of end regions(mm)	2.42935	NA
total area of end regions(mm^2)	12	NA
irregularity	3.30693	NA
area of end region 1(mm^2)	5	NA
radius of end region 1(mm)	0.889838	NA
irregularity of end region 1	0.49751	NA
area of end region 2(mm^2)	7	NA
radius of end region 2(mm)	1.53952	NA
irregularity of end region 2	1.0637	NA
qa	0.157924	NA
nqa	0.242635	NA
gfa	0.086224	NA
iso	0.389791	NA
dec_t	0.799895	NA
inc_t	0.0707445	NA
ICBM152_adult.T1W	182.279	NA
ICBM152_adult.WM	67.701	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.08347	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.96843	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.16653	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.08497	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.34206	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.24927	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	2.02286	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.12091	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.15408	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.12532	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.19315	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.17233	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.51696	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.07532	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.18577	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.13534	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.29984	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.20061	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.13105	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.13025	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.13525	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.4174	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.1032	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.4808	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.13402	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.33193	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.1664	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.17048	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.26416	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.07694	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.14224	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.15491	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	2.21625	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.11162	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	1.71774	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.30121	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.13752	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.15283	NA

Negative Correlations (FDR = 0.000569)

V1	V2	V3	V4
Tract Name	Fornix_R	Fornix_L	NA
number of tracts	472	323	NA
mean length(mm)	56.3187	54.2544	NA
span(mm)	24.3503	21.8941	NA
curl	2.31286	2.47804	NA
elongation	7.91408	7.60621	NA
diameter(mm)	7.11627	7.13292	NA
volume(mm^3)	2240	2168	NA
trunk volume(mm^3)	1600	1945	NA
branch volume(mm^3)	640	223	NA
total surface area(mm^2)	6687	5794	NA
total radius of end regions(mm)	11.6013	10.1819	NA
total area of end regions(mm^2)	450	354	NA
irregularity	5.31099	4.7657	NA
area of end region 1(mm^2)	221	183	NA
radius of end region 1(mm)	5.87004	5.48114	NA
irregularity of end region 1	0.489824	0.515751	NA
area of end region 2(mm^2)	229	171	NA
radius of end region 2(mm)	5.73128	4.70076	NA
irregularity of end region 2	0.450627	0.405965	NA
qa	0.146622	0.144223	NA
inc_t	0.0389089	0.0320434	NA
dec_t	1.28577	1.25423	NA
qa_map	0.148483	0.145788	NA
ICBM152_adult.T1W	156.983	169.642	NA
ICBM152_adult.WM	48.8775	59.5358	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3

Glass Brain displaying tracts that had AD negatively correlated with loop angular error rad3

Men

Positive Correlations (FDR = 0.039599)

V1	V2	V3	V4	V5	V6
Tract Name	Fornix_L	Fornix_R	Thalamic_Radiation_Superior_L	Cerebellum_L	NA
number of tracts	690	138	57	17	NA
mean length(mm)	56.4607	55.5946	55.5539	51.8947	NA
span(mm)	20.5197	21.789	18.2686	24.0388	NA
curl	2.75154	2.5515	3.04096	2.15879	NA
elongation	6.416	9.04383	11.2817	17.1774	NA
diameter(mm)	8.79998	6.14725	4.92425	3.0211	NA
volume(mm^3)	3434	1650	1058	372	NA
trunk volume(mm^3)	2866	1003	92	190	NA
branch volume(mm^3)	568	647	966	182	NA
total surface area(mm^2)	8396	5807	4734	2490	NA
total radius of end regions(mm)	12.3729	8.02095	10.1229	5.17297	NA
total area of end regions(mm^2)	564	178	80	23	NA
irregularity	5.37891	5.40864	5.50837	5.05547	NA
area of end region 1(mm^2)	299	90	41	11	NA
radius of end region 1(mm)	6.87359	4.02222	4.64991	2.1574	NA
irregularity of end region 1	0.496416	0.564728	1.65674	1.32929	NA
area of end region 2(mm^2)	265	88	39	12	NA
radius of end region 2(mm)	5.49928	3.99872	5.47302	3.01558	NA
irregularity of end region 2	0.358522	0.570834	2.4129	2.38072	NA
qa	0.14283	0.122241	0.164886	0.121131	NA
inc_t	0.864238	0.560884	0.797165	0.922218	NA
dec_t	0.0615795	0.222765	0.0580371	0.179455	NA
qa_map	0.144509	0.124196	0.167269	0.121924	NA
ICBM152_adult.T1W	176.556	172.057	186.132	163.411	NA
ICBM152_adult.WM	63.9333	50.8381	110.898	12.9664	NA

Negative Correlations (FDR = 1.000000)

Not significant

Figures

Slice overlay image displaying ROIs with tracts that had AD positively correlated with loop Angular error rad3 in men

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in Men

Glass Brain displaying tracts that had AD positively correlated with loop angular error rad3

Women

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.000311)

V1	V2	V3	V4	V5	V6	V7	V8	V9
Tract Name	Fornix_L	Fornix_R	Corpus_Callosum_Tapetum	Thalamic_Radiation_Superior_L	Optic_Radiation_L	Inferior_Fronto_Occipital_Fasciculus_L	Cingulum_Frontal_Parietal_L	NA
number of tracts	777	264	136	100	28	21	14	NA
mean length(mm)	54.7772	54.5156	56.5829	53.4262	55.6513	55.3451	54.7235	NA
span(mm)	22.2491	23.5185	22.6068	17.27	26.8088	26.5185	23.3578	NA
curl	2.462	2.31799	2.50292	3.09358	2.07586	2.08704	2.34283	NA
elongation	6.22806	8.31832	8.08618	9.06042	16.6211	17.4153	19.572	NA
diameter(mm)	8.79522	6.55368	6.99748	5.89665	3.34823	3.17796	2.79601	NA
volume(mm^3)	3328	1839	2176	1459	490	439	336	NA
trunk volume(mm^3)	2909	1252	0	314	480	293	97	NA
branch volume(mm^3)	419	587	2176	1145	10	146	239	NA
total surface area(mm^2)	9002	5950	6595	6111	2045	2015	1720	NA
total radius of end regions(mm)	11.7168	10.9776	25.9182	15.2668	5.30434	5.95009	5.41645	NA
total area of end regions(mm^2)	685	316	204	135	45	38	22	NA
irregularity	5.94761	5.30103	5.30198	6.17451	3.49344	3.64669	3.57822	NA
area of end region 1(mm^2)	336	147	99	69	20	18	11	NA
radius of end region 1(mm)	5.90876	5.32452	13.2983	7.38499	1.82781	2.98168	1.75487	NA
irregularity of end region 1	0.32644	0.605889	5.61183	2.48314	0.524786	1.55167	0.879525	NA
area of end region 2(mm^2)	349	169	105	66	25	20	11	NA
radius of end region 2(mm)	5.80805	5.65309	12.62	7.88186	3.47653	2.96842	3.66157	NA
irregularity of end region 2	0.303658	0.594065	4.76516	2.95708	1.5188	1.38411	3.82907	NA
qa	0.15043	0.144043	0.347229	0.169859	0.239159	0.233222	0.129628	NA
inc_t	0.0112405	0.0435657	0.0453382	0.0124905	0.0227154	0.0178282	0.0107608	NA
dec_t	1.77646	1.26598	1.23949	1.49627	1.23563	1.19444	1.47612	NA
qa_map	0.152094	0.145901	0.350949	0.172517	0.241862	0.236027	0.133102	NA
ICBM152_adult.T1W	167.752	160.526	207.444	185.67	182.794	177.459	197.821	NA
ICBM152_adult.WM	60.7431	52.0525	207.486	113.34	142.062	132.805	128.812	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in women

Glass Brain displaying tracts that had AD negatively correlated with loop angular error rad3 in women

pre

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.035371)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17	V18	V19	V20	V21	V22	V23	V24	V25	V26	V27	V28	V29
Tract Name	Fornix_L	Fornix_R	Corpus_Callosum_Forceps_Major	Cerebellum_R	Corpus_Callosum_Tapetum	Thalamic_Radiation_Superior_L	Optic_Radiation_L	Corpus_Callosum_Body	Corticospinal_Tract_L	Thalamic_Radiation_Superior_R	Arcuate_Fasciculus_R	Corticostriatal_Tract_Posterior_R	Dentatorubrothalamic_Tract_R	Cingulum_Frontal_Parietal_L	Thalamic_Radiation_Posterior_R	Inferior_Fronto_Occipital_Fasciculus_L	Corticospinal_Tract_R	Corticostriatal_Tract_Posterior_L	Anterior_Commissure	Inferior_Longitudinal_Fasciculus_L	Superior_Longitudinal_Fasciculus1_L	Cingulum_Frontal_Parahippocampal_L	Optic_Radiation_R	Dentatorubrothalamic_Tract_L	Corticopontine_Tract_Occipital_R	Inferior_Fronto_Occipital_Fasciculus_R	Inferior_Longitudinal_Fasciculus_R	NA
number of tracts	1685	1199	351	343	324	158	146	86	49	48	45	44	40	39	39	33	29	28	28	17	16	14	14	13	11	10	10	NA
mean length(mm)	59.6412	58.0065	60.8296	54.2152	59.1429	54.0044	55.9949	54.8251	55.8454	55.0106	56.1465	56.4236	57.4546	55.5984	58.4165	55.948	56.0753	54.7354	58.0158	56.1331	58.0123	69.2925	53.5805	55.706	55.265	60.6201	61.2367	NA
span(mm)	22.9071	23.8164	24.8588	25.0262	21.7102	17.7747	26.8417	21.2492	27.0833	17.0655	23.6048	26.0487	27.8978	24.6666	26.9714	26.8945	27.1452	26.4196	27.8224	26.934	22.5417	24.0149	21.3986	25.318	24.7652	25.8778	26.4925	NA
curl	2.60361	2.43557	2.44701	2.16634	2.7242	3.03827	2.08612	2.58011	2.06198	3.2235	2.37861	2.16608	2.05947	2.25399	2.16587	2.08028	2.06576	2.07177	2.08522	2.0841	2.57355	2.8854	2.50392	2.20025	2.23156	2.34255	2.31147	NA
elongation	5.17571	5.78469	6.17113	5.81837	4.45543	7.28479	7.92053	6.18533	10.808	11.8506	12.3938	9.66282	12.1623	12.2331	11.5927	10.9987	12.8552	14.5784	13.6097	14.148	18.9501	25.6232	22.9687	16.6626	18.98	19.7841	18.6594	NA
diameter(mm)	11.5233	10.0276	9.85713	9.31793	13.2743	7.4133	7.06959	8.86373	5.16702	4.64202	4.53021	5.83925	4.72397	4.54493	5.03907	5.08678	4.36206	3.75454	4.26282	3.96757	3.06132	2.70429	2.33276	3.34317	2.91175	3.06408	3.28181	NA
volume(mm^3)	6220	4581	4642	3697	8185	2331	2198	3383	1171	931	905	1511	1007	902	1165	1137	838	606	828	694	427	398	229	489	368	447	518	NA
trunk volume(mm^3)	4625	3376	1474	2164	1719	619	1278	313	229	173	551	0	381	0	297	89	341	185	156	150	262	148	187	0	159	176	135	NA
branch volume(mm^3)	1595	1205	3168	1533	6466	1712	920	3070	942	758	354	1511	626	902	868	1048	497	421	672	544	165	250	42	489	209	271	383	NA
total surface area(mm^2)	16874	12357	13895	10985	24752	8230	7751	18335	4908	4344	3697	7085	4231	4589	6298	4818	2966	2769	3574	3909	2092	2538	1320	3470	2100	2545	2952	NA
total radius of end regions(mm)	18.6138	14.286	16.1283	12.7431	34.414	13.977	12.6925	37.7853	10.6562	15.2091	7.03034	18.0799	7.78003	13.4799	18.2766	11.2155	5.13545	9.18548	10.6475	31.4193	6.14976	14.1214	3.776	27.9019	8.38903	8.03779	10.42	NA
total area of end regions(mm^2)	1434	1047	459	422	525	210	200	151	74	65	71	76	60	62	61	63	51	44	45	32	22	20	19	23	18	18	17	NA
irregularity	7.81528	6.76222	7.37639	6.92166	10.0356	6.54349	6.23253	12.0098	5.41412	5.41486	4.62657	6.84498	4.96205	5.78068	6.81031	5.38876	3.85974	4.28892	4.60004	5.58691	3.74958	4.31124	3.36161	5.93088	4.15399	4.36135	4.67564	NA
area of end region 1(mm^2)	699	517	236	214	274	122	101	78	38	39	30	39	28	34	32	32	27	21	21	16	15	9	8	12	10	9	8	NA
radius of end region 1(mm)	9.85683	7.82422	8.95097	5.53761	17.7877	7.46154	6.22379	23.6031	6.03908	6.41504	2.50096	11.8635	3.75953	6.69211	9.63469	5.41967	2.43932	4.49027	5.22145	14.4253	3.89069	8.77244	1.60502	17.6612	2.71966	5.70335	6.60831	NA
irregularity of end region 1	0.436664	0.371999	1.06654	0.450175	3.62775	1.43366	1.20486	22.4386	3.01514	3.31501	0.655	11.3374	1.58584	4.13806	9.1133	2.88367	0.692347	3.0163	4.07862	40.858	3.17038	26.8626	1.01163	81.6603	2.32369	11.3545	17.1491	NA
area of end region 2(mm^2)	735	530	223	208	251	88	99	73	36	26	41	37	32	28	29	31	24	23	24	16	7	11	11	11	8	9	9	NA
radius of end region 2(mm)	8.75694	6.46176	7.17732	7.20545	16.6263	6.51546	6.46869	14.1822	4.61713	8.79402	4.52938	6.21637	4.0205	6.78777	8.6419	5.79581	2.69613	4.69522	5.42602	16.994	2.25907	5.34899	2.17098	10.2406	5.66937	2.33445	3.81169	NA
irregularity of end region 2	0.327769	0.247501	0.725721	0.784166	3.45995	1.5155	1.32784	8.65591	1.86034	9.3444	1.57197	3.28112	1.58694	5.16947	8.0904	3.40421	0.951524	3.01116	3.8539	56.7053	2.2904	8.17149	1.34607	29.951	12.622	1.90228	5.07156	NA
qa	0.157953	0.147377	0.276999	0.119935	0.293632	0.17043	0.248632	0.276744	0.280566	0.16994	0.184989	0.232648	0.239544	0.190917	0.23914	0.244837	0.239111	0.248207	0.23756	0.221721	0.157736	0.155303	0.175694	0.252504	0.227496	0.218685	0.216257	NA
inc_t	0.0533682	0.0447957	0.212923	0.0947042	0.263854	0.0688215	0.123121	0.33186	0.0791501	0.0589379	0.364758	0.202199	0.195573	0.0731222	0.24267	0.148866	0.137403	0.0661658	0.168432	0.254222	0.013004	0.120199	0.120359	0.118506	0.116006	0.424518	0.416369	NA
dec_t	1.98122	2.33931	1.29542	1.43644	0.99193	1.96051	1.39085	1.073	1.91085	2.12119	0.880185	1.20881	1.92907	1.67791	1.22317	1.40459	2.03968	1.47573	1.25475	1.03132	2.02087	1.611	1.90301	1.65113	1.06195	0.700171	0.724654	NA
qa_map	0.16001	0.149354	0.280055	0.121076	0.298166	0.172874	0.25143	0.28092	0.282674	0.171881	0.195624	0.235857	0.241702	0.193697	0.241389	0.24772	0.241154	0.250855	0.240251	0.224361	0.159722	0.15673	0.178218	0.254572	0.229975	0.221174	0.219225	NA
ICBM152_adult.T1W	166.911	165.017	184.446	173.6	198.524	185.627	200.303	203.58	213.797	178.087	225.652	219.296	216.668	205.07	211.669	196.376	217.573	199.171	191.824	205.264	198.27	177.613	157.136	209.627	223.586	223.11	223.302	NA
ICBM152_adult.WM	57.538	55.7329	148.434	35.9728	183.485	119.879	177.202	194.789	234.528	110.164	248.284	234.305	238.022	178.469	217.584	172.363	242.327	166.839	167.26	186.337	131.657	90.4001	98.8823	210.189	246.702	249.061	249.12	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in pre menopausal women

Glass Brain displaying tracts that had AD negatively correlated with loop angular error rad3 in women

peri

Positive Correlations (not significant) (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.007165)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17	V18	V19	V20	V21	V22	V23	V24	V25	V26	V27	V28	V29	V30	V31	V32	V33	V34	V35	V36
Tract Name	Corpus_Callosum_Tapetum	Cerebellum_R	Corpus_Callosum_Forceps_Major	Fornix_L	Corpus_Callosum_Body	Cerebellum_L	Inferior_Longitudinal_Fasciculus_L	Middle_Cerebellar_Peduncle	Corticostriatal_Tract_Posterior_R	Arcuate_Fasciculus_R	Fornix_R	Optic_Radiation_L	Corticospinal_Tract_R	Inferior_Fronto_Occipital_Fasciculus_R	Inferior_Longitudinal_Fasciculus_R	Dentatorubrothalamic_Tract_R	Inferior_Fronto_Occipital_Fasciculus_L	Corticospinal_Tract_L	Corticopontine_Tract_Parietal_L	Corticostriatal_Tract_Posterior_L	Dentatorubrothalamic_Tract_L	Cingulum_Parolfactory_R	Superior_Longitudinal_Fasciculus2_L	Thalamic_Radiation_Posterior_R	Thalamic_Radiation_Posterior_L	Medial_Lemniscus_R	Arcuate_Fasciculus_L	Thalamic_Radiation_Anterior_R	Middle_Longitudinal_Fasciculus_R	Corticopontine_Tract_Parietal_R	Thalamic_Radiation_Superior_L	Corpus_Callosum_Forceps_Minor	Cingulum_Frontal_Parietal_R	Superior_Longitudinal_Fasciculus2_R	NA
number of tracts	212	94	88	83	52	50	49	37	36	35	35	33	32	31	29	27	24	21	20	19	18	17	17	17	15	15	14	13	12	12	12	12	11	10	NA
mean length(mm)	67.5974	54.625	62.3296	60.9278	59.3152	53.7267	56.9462	54.5994	57.7391	62.9293	65.9522	58.37	60.7648	56.7111	58.7034	59.7927	58.4147	57.9135	60.7126	55.3643	56.9022	62.5969	55.6631	57.543	57.475	60.4071	59.4428	53.0881	53.0105	55.497	56.0158	58.5037	55.8333	54.6162	NA
span(mm)	24.1238	25.0194	24.019	21.3055	22.6813	24.8614	27.4303	22.8621	25.3664	23.3236	23.3556	28.0694	28.846	25.6269	26.1044	27.0661	27.4929	27.4844	28.1545	25.2817	25.833	28.3285	23.2692	24.058	25.1689	26.6415	24.8925	25.2087	22.7224	25.6249	22.993	23.5498	25.9975	21.0983	NA
curl	2.80211	2.18331	2.59501	2.85972	2.61516	2.16104	2.07603	2.3882	2.2762	2.69809	2.82383	2.07949	2.10652	2.21295	2.24879	2.20913	2.12472	2.10714	2.15641	2.18989	2.2027	2.20968	2.39214	2.39184	2.28358	2.26741	2.38798	2.10595	2.33296	2.16575	2.43621	2.48425	2.14764	2.58866	NA
elongation	6.45124	6.53892	7.74319	9.76215	8.77212	8.4079	9.45328	9.22553	9.26554	12.0767	15.1704	11.7309	11.9162	9.42972	9.67036	10.3909	12.3046	13.8265	17.3039	12.7259	13.2679	17.1234	15.2297	12.9743	13.5265	15.7828	14.2445	14.5773	14.2151	15.4144	16.0483	16.7432	16.2137	16.3783	NA
diameter(mm)	10.4782	8.35382	8.0496	6.24123	6.76179	6.39003	6.02396	5.91829	6.2316	5.21081	4.34742	4.97574	5.09935	6.01408	6.07044	5.75435	4.74738	4.18858	3.50861	4.35051	4.28871	3.65562	3.65492	4.43517	4.24907	3.8274	4.17302	3.64182	3.72918	3.60035	3.49046	3.49417	3.44358	3.33467	NA
volume(mm^3)	5829	2994	3172	1864	2130	1723	1623	1502	1761	1342	979	1135	1241	1611	1699	1555	1034	798	587	823	822	657	584	889	815	695	813	553	579	565	536	561	520	477	NA
trunk volume(mm^3)	191	464	79	237	161	285	143	0	0	119	179	0	135	0	0	0	0	187	185	0	67	0	77	64	111	0	0	0	0	0	63	61	0	68	NA
branch volume(mm^3)	5638	2530	3093	1627	1969	1438	1480	1502	1761	1223	800	1135	1106	1611	1699	1555	1034	611	402	823	755	657	507	825	704	695	813	553	579	565	473	500	520	409	NA
total surface area(mm^2)	27153	15359	18546	10038	14407	8935	9141	10322	12231	6923	5558	5969	7466	11886	12658	11898	7107	4910	3742	7515	6346	3613	5028	6704	6773	5613	5635	4321	4278	4484	4566	4651	4207	4537	NA
total radius of end regions(mm)	36.2285	17.1196	29.8423	16.6934	32.0269	9.63896	19.6174	29.8698	21.9082	22.8078	13.7998	12.7741	17.1963	39.5043	25.6318	43.2139	23.0934	18.3161	12.0792	26.6615	19.7545	16.4863	39.7047	22.5346	26.4882	29.8633	26.392	18.0525	20.9461	16.6918	19.8912	20.0908	25.8564	62.244	NA
total area of end regions(mm^2)	311	148	148	113	84	76	81	66	61	58	52	51	52	58	56	51	37	35	30	31	30	28	24	33	27	26	28	25	20	20	20	22	20	14	NA
irregularity	12.2026	10.7136	11.7661	8.40256	11.4339	8.28423	8.48198	10.1679	10.8204	6.72027	6.17032	6.5419	7.66957	11.093	11.3066	11.0073	8.15755	6.44295	5.59165	9.93138	8.27741	5.02579	7.86684	8.36146	8.82791	7.72776	7.23093	7.11407	6.88836	7.14334	7.4335	7.24216	6.96497	7.92946	NA
area of end region 1(mm^2)	151	69	75	68	43	36	39	34	31	30	29	26	24	30	28	25	19	17	16	16	16	14	13	17	13	13	14	12	10	9	9	12	10	7	NA
radius of end region 1(mm)	19.2595	7.39459	17.616	10.2798	16.2467	3.74487	11.1076	20.2928	11.7799	11.0649	9.83014	6.13434	8.67139	21.101	12.6851	21.0917	12.0199	9.03839	5.92979	16.5523	13.0864	8.58022	21.57	12.9216	15.2659	14.5337	13.9682	8.61289	9.27353	10.6266	10.4781	8.92156	11.5164	27.9623	NA
irregularity of end region 1	7.7173	2.4896	12.9988	4.88212	19.2846	1.22383	9.93853	38.0501	14.0628	12.8211	10.4682	4.54686	9.84274	46.6266	18.0542	55.9027	23.8892	15.0968	6.90412	53.7954	33.6258	16.5203	112.436	30.8555	56.3189	51.0456	43.7828	19.4208	27.0172	39.4185	38.3243	20.8377	41.6661	350.911	NA
area of end region 2(mm^2)	160	79	73	45	41	40	42	32	30	28	23	25	28	28	28	26	18	18	14	15	14	14	11	16	14	13	14	13	10	11	11	10	10	7	NA
radius of end region 2(mm)	16.9689	9.72505	12.2263	6.41359	15.7802	5.89409	8.5098	9.57701	10.1283	11.7429	3.96966	6.6398	8.5249	18.4034	12.9467	22.1222	11.0734	9.27774	6.14938	10.1093	6.66811	7.90609	18.1347	9.61299	11.2223	15.3296	12.4238	9.43959	11.6725	6.06515	9.4131	11.1692	14.34	34.2817	NA
irregularity of end region 2	5.65379	3.76103	6.43306	2.8717	19.0806	2.7285	5.41676	9.0045	10.7425	15.4719	2.15242	5.54012	8.154	38.0002	18.8066	59.1336	21.4014	15.0232	8.48563	21.4041	9.97762	14.0264	93.9242	18.1446	28.2609	56.7895	34.6363	21.5334	42.8037	10.5061	25.306	39.1916	64.6021	527.445	NA
qa	0.302469	0.115122	0.328523	0.156005	0.303395	0.130299	0.203897	0.207891	0.230063	0.229877	0.157124	0.262253	0.315042	0.228771	0.212734	0.224848	0.26588	0.325433	0.331839	0.244754	0.251276	0.201587	0.168289	0.224764	0.221296	0.245241	0.235006	0.186345	0.204521	0.261291	0.152012	0.230798	0.210345	0.156209	NA
inc_t	0.11332	0.176529	0.170949	0.104548	0.173696	0.269057	0.24546	0.232708	0.133747	0.130946	0.298361	0.183057	0.286396	0.203036	0.202457	0.287431	0.220464	0.294903	0.112926	0.20977	0.319572	0.343225	0.225014	0.183011	0.343114	0.221861	0.178445	0.273357	0.157423	0.230378	0.0628717	0.230093	0.390633	0.260526	NA
dec_t	1.25161	1.35105	1.12357	0.960263	1.11127	1.02071	0.949492	0.988011	1.12719	1.21471	0.49499	0.698782	0.987605	1.11077	0.994962	0.994876	0.924558	0.927729	0.985446	1.04016	0.899939	0.607022	1.07939	1.18558	0.857885	1.12425	1.01826	0.919524	1.41875	1.16621	1.02543	0.752797	0.682759	1.16607	NA
qa_map	0.306131	0.116063	0.33232	0.158166	0.309035	0.131473	0.206754	0.212633	0.233932	0.235175	0.15916	0.265663	0.318853	0.231916	0.216506	0.227405	0.26912	0.328409	0.335818	0.247869	0.253603	0.204908	0.174908	0.228546	0.224046	0.24863	0.240242	0.188724	0.210031	0.264834	0.154655	0.237238	0.213109	0.163751	NA
ICBM152_adult.T1W	203.869	176.857	192.912	177.707	200.794	157.384	221.534	212.589	220.745	226.224	168.711	204.408	208.967	213.408	220.332	207.688	209.523	210.453	214.848	216.487	208.504	196.137	222.028	221.481	214.164	209.948	223.733	205.589	221.835	221.059	194.004	212.51	197.289	221.326	NA
ICBM152_adult.WM	199.963	54.5659	175.217	76.8679	194.82	15.9388	228.603	221.839	238.384	251.252	75.6667	186.231	233.223	212.017	234.715	206.183	207.036	238.944	242.777	226.905	218.694	150.835	248.022	235.069	216.827	217.393	251.341	180.12	245.304	248.762	130.658	217.221	156.769	237.922	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in peri menopausal women

Glass Brain displaying tracts that had AD negatively correlated with loop angular error rad3 in peri menopausal women

post

Positive Correlations (FDR = 1.000000)

No Significant Findings

Negative Correlations (FDR = 0.168946)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17
Tract Name	Cerebellum_R	Cerebellum_L	Fornix_L	Corpus_Callosum_Forceps_Major	Thalamic_Radiation_Superior_L	Corpus_Callosum_Tapetum	Corpus_Callosum_Body	Inferior_Fronto_Occipital_Fasciculus_R	Middle_Cerebellar_Peduncle	Medial_Lemniscus_R	Arcuate_Fasciculus_L	Inferior_Longitudinal_Fasciculus_R	Corticostriatal_Tract_Superior_R	Cingulum_Parolfactory_R	Fornix_R	NA
number of tracts	102	78	53	38	35	30	20	17	15	14	13	13	12	10	10	NA
mean length(mm)	55.3647	53.7846	59.0651	57.5914	62.9714	57.8706	54.9034	51.8985	57.7442	57.1366	51.3937	53.2487	54.1956	56.2217	58.7948	NA
span(mm)	25.5989	24.5375	22.5239	23.5183	17.2031	24.0899	19.3197	21.5553	21.8392	27.4986	21.4614	23.9642	25.2941	26.3961	24.4963	NA
curl	2.16278	2.19194	2.62233	2.44879	3.66047	2.40227	2.84183	2.4077	2.64407	2.0778	2.39471	2.22201	2.14262	2.12992	2.40015	NA
elongation	6.28338	6.51268	10.6795	10.9379	18.5328	9.55	12.0783	11.266	16.0642	19.0899	13.9866	14.7642	18.846	19.0401	18.961	NA
diameter(mm)	8.8113	8.25844	5.53071	5.26532	3.39783	6.05975	4.54563	4.60665	3.59459	2.99303	3.6745	3.60662	2.8757	2.9528	3.10082	NA
volume(mm^3)	3376	2881	1419	1254	571	1669	891	865	586	402	545	544	352	385	444	NA
trunk volume(mm^3)	417	0	0	0	197	0	0	121	135	0	97	178	0	0	0	NA
branch volume(mm^3)	2959	2881	1419	1254	374	1669	891	744	451	402	448	366	352	385	444	NA
total surface area(mm^2)	17650	17201	7585	8911	3304	12509	7223	6450	4385	2847	4545	4137	2513	2559	2811	NA
total radius of end regions(mm)	15.1831	14.1163	19.9064	27.8037	15.3597	44.4788	37.3147	57.3845	25.4816	12.5273	28.7831	25.0446	11.2597	10.5047	13.3603	NA
total area of end regions(mm^2)	150	117	71	58	37	56	31	30	25	20	23	23	20	17	19	NA
irregularity	11.5165	12.3267	7.39084	9.35392	4.91525	11.3543	9.21243	8.58755	6.72452	5.29923	7.66083	6.85688	5.13256	4.90663	4.90789	NA
area of end region 1(mm^2)	69	62	32	29	22	28	15	15	12	10	12	11	10	9	9	NA
radius of end region 1(mm)	6.19716	6.07237	12.3985	16.3066	11.3451	16.1104	18.7138	30.2086	14.8513	5.91432	12.8758	14.6159	5.13389	4.71246	5.73648	NA
irregularity of end region 1	1.74858	1.86842	15.0918	28.8058	18.3801	29.121	73.347	191.126	57.7426	10.989	43.403	61.0106	8.28024	7.7518	11.4868	NA
area of end region 2(mm^2)	81	55	39	29	15	28	16	15	13	10	11	12	10	8	10	NA
radius of end region 2(mm)	8.98589	8.04394	7.50789	11.4971	4.01459	28.3684	18.6009	27.1759	10.6303	6.61302	15.9072	10.4288	6.1258	5.79229	7.62379	NA
irregularity of end region 2	3.13175	3.69594	4.54068	14.3195	3.37552	90.2944	67.9354	154.677	27.3087	13.7388	72.2682	28.4732	11.789	13.1753	18.2596	NA
qa	0.113151	0.12184	0.161697	0.308793	0.183618	0.274503	0.28646	0.237672	0.214778	0.238927	0.217827	0.279586	0.230612	0.196094	0.151264	NA
inc_t	0.816666	0.925364	0.651679	0.518876	0.650656	0.919752	0.707698	0.747735	0.805524	0.471018	0.561236	1.03635	0.747849	0.933001	0.745048	NA
dec_t	1.41653	0.950368	1.42791	1.74507	1.00191	1.26443	1.59777	1.34184	1.98454	1.87219	1.61755	1.0373	1.42188	1.55224	0.895307	NA
qa_map	0.114024	0.123311	0.163743	0.312074	0.185976	0.279364	0.292542	0.240347	0.218347	0.242337	0.223544	0.283117	0.234894	0.200606	0.153154	NA
ICBM152_adult.T1W	174.562	166.643	174.407	189.001	183.162	203.181	210.876	213.426	200.977	217.451	221.297	223.284	217.178	185.308	157.86	NA
ICBM152_adult.WM	44.8044	29.3073	72.36	168.962	112.914	194.57	224.325	202.461	191.769	239.529	246.863	242.547	244.024	115.3	53.4921	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in post menopausal women

Glass Brain displaying tracts that had AD positively and negatively correlated with loop angular error rad3 in post menopausal women

Peri + Post

Positive Correlations (FDR = 1.000000)

No significant

Negative Correlations (FDR = 0.059775)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11
Tract Name	Corpus_Callosum_Tapetum	Fornix_L	Corpus_Callosum_Body	Corpus_Callosum_Forceps_Major	Cerebellum_R	Fornix_R	Thalamic_Radiation_Superior_L	Inferior_Fronto_Occipital_Fasciculus_L	Cingulum_Frontal_Parietal_L	NA
number of tracts	355	257	115	101	91	86	64	18	13	NA
mean length(mm)	58.6514	56.1715	55.7838	58.46	53.1717	55.1965	55.7154	55.0104	57.842	NA
span(mm)	23.3245	21.5463	22.6171	22.9177	25.3379	24.176	17.6719	26.2259	23.4435	NA
curl	2.51458	2.60701	2.46644	2.55087	2.0985	2.28311	3.15276	2.09756	2.46729	NA
elongation	5.85022	7.83772	8.94747	9.55422	9.04863	11.5329	10.3502	19.1372	20.5761	NA
diameter(mm)	10.0255	7.16683	6.23459	6.11876	5.87621	4.78601	5.38303	2.87453	2.81113	NA
volume(mm^3)	4630	2266	1703	1719	1442	993	1268	357	359	NA
trunk volume(mm^3)	0	1088	1167	0	1169	248	240	146	77	NA
branch volume(mm^3)	4630	1178	536	1719	273	745	1028	211	282	NA
total surface area(mm^2)	15473	8507	6432	7888	5767	3549	6548	1959	2421	NA
total radius of end regions(mm)	34.7232	12.6337	9.04735	26.6263	7.68556	8.50915	14.9718	10.0683	10.4136	NA
total area of end regions(mm^2)	484	296	144	151	115	106	87	30	18	NA
irregularity	8.37606	6.72641	5.8868	7.01931	5.87519	4.27632	6.94955	3.94342	4.73937	NA
area of end region 1(mm^2)	241	143	77	76	55	39	50	16	10	NA
radius of end region 1(mm)	17.7094	7.12879	4.67275	16.8206	3.45216	4.60113	8.70118	5.44672	5.41207	NA
irregularity of end region 1	4.08829	1.11647	0.890849	11.6955	0.680721	1.70535	4.75703	5.82506	9.20188	NA
area of end region 2(mm^2)	243	153	67	75	60	67	37	14	8	NA
radius of end region 2(mm)	17.0138	5.50492	4.3746	9.80573	4.23341	3.90802	6.27062	4.62154	5.00156	NA
irregularity of end region 2	3.74236	0.622245	0.897329	4.02762	0.938379	0.716125	3.33863	4.79287	9.82359	NA
qa	0.311363	0.142207	0.368306	0.381801	0.114718	0.151168	0.168277	0.235705	0.140609	NA
inc_t	0.114101	0.151211	0.0657514	0.0886674	0.0759451	0.420681	0.0690649	0.118043	0.104864	NA
dec_t	1.16005	0.88814	1.39937	1.28248	1.58569	0.336875	0.835447	0.866991	0.929206	NA
qa_map	0.314968	0.143827	0.373308	0.386492	0.115582	0.153138	0.170431	0.238826	0.14382	NA
ICBM152_adult.T1W	193.212	171.879	208.448	193.624	185.582	156.697	183.835	176.15	196.301	NA
ICBM152_adult.WM	173.326	62.7723	216.15	176.615	77.1955	49.1918	112.984	132.099	129.999	NA

Figures

Slice overlay image displaying ROIs with tracts that had AD negatively correlated with loop angular error rad3 in peri and post menopausal women

Glass Brain displaying tracts that had AD negatively correlated with loop angular error rad3 in peri and post menopausal women

RD

All subjects

Positive Correlations (FDR = 0.050000)

V1	V2	V3
Tract Name	Fornix_L	NA
number of tracts	14	NA
mean length(mm)	53.7203	NA
span(mm)	19.8139	NA
curl	2.71124	NA
elongation	17.6467	NA
diameter(mm)	3.04421	NA
volume(mm^3)	391	NA
trunk volume(mm^3)	356	NA
branch volume(mm^3)	35	NA
total surface area(mm^2)	1644	NA
total radius of end regions(mm)	3.98723	NA
total area of end regions(mm^2)	20	NA
irregularity	3.19992	NA
area of end region 1(mm^2)	10	NA
radius of end region 1(mm)	1.57332	NA
irregularity of end region 1	0.777652	NA
area of end region 2(mm^2)	10	NA
radius of end region 2(mm)	2.41391	NA
irregularity of end region 2	1.83059	NA
qa	0.165968	NA
inc_t	0.0694185	NA
dec_t	0.584835	NA
qa_map	0.167843	NA
ICBM152_adult.T1W	181.584	NA
ICBM152_adult.WM	70.7534	NA

Negative Correlations (FDR = 0.000506)

V1	V2	V3	V4	V5
Tract Name	Fornix_R	Fornix_L	Thalamic_Radiation_Superior_L	NA
number of tracts	389	361	16	NA
mean length(mm)	55.8954	56.3367	53.3834	NA
span(mm)	24.0949	21.6483	12.4267	NA
curl	2.3198	2.60236	4.29585	NA
elongation	8.16567	7.06055	18.7739	NA
diameter(mm)	6.84517	7.97908	2.84349	NA
volume(mm^3)	2057	2817	339	NA
trunk volume(mm^3)	1230	2308	149	NA
branch volume(mm^3)	827	509	190	NA
total surface area(mm^2)	6734	7792	2337	NA
total radius of end regions(mm)	12.9366	11.7828	11.5205	NA
total area of end regions(mm^2)	364	404	23	NA
irregularity	5.60226	5.51766	4.90062	NA
area of end region 1(mm^2)	175	199	12	NA
radius of end region 1(mm)	7.03241	5.94405	6.47763	NA
irregularity of end region 1	0.88781	0.557779	10.985	NA
area of end region 2(mm^2)	189	205	11	NA
radius of end region 2(mm)	5.90415	5.83879	5.04285	NA
irregularity of end region 2	0.579433	0.522446	7.26289	NA
qa	0.136099	0.15389	0.183768	NA
inc_t	0.0306706	0.0570189	0.0282008	NA
dec_t	1.38082	0.869079	0.787288	NA
qa_map	0.138295	0.155717	0.186727	NA
ICBM152_adult.T1W	144.679	171.739	183.31	NA
ICBM152_adult.WM	32.6306	61.603	103.381	NA

Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3

Glass Brain displaying tracts that had AD positively and negatively correlated with loop angular error rad3 in women

Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3

Men

Positive Correlations (FDR = 0.040025)

V1	V2	V3	V4	V5	V6
Tract Name	Fornix_L	Fornix_R	Thalamic_Radiation_Superior_L	Corpus_Callosum_Forceps_Major	NA
number of tracts	1041	133	60	11	NA
mean length(mm)	59.0382	56.5103	55.3754	51.8294	NA
span(mm)	20.8984	21.9502	17.0923	21.6841	NA
curl	2.825	2.57448	3.23979	2.3902	NA
elongation	6.7454	10.0082	10.6765	16.5548	NA
diameter(mm)	8.75236	5.64637	5.18668	3.13079	NA
volume(mm^3)	3552	1415	1170	399	NA
trunk volume(mm^3)	2898	1056	239	236	NA
branch volume(mm^3)	654	359	931	163	NA
total surface area(mm^2)	9658	5611	5233	2513	NA
total radius of end regions(mm)	14.031	9.20754	10.799	6.57739	NA
total area of end regions(mm^2)	717	161	81	17	NA
irregularity	5.94948	5.59749	5.79955	4.92961	NA
area of end region 1(mm^2)	382	72	35	8	NA
radius of end region 1(mm)	7.3392	4.32519	5.99898	3.33909	NA
irregularity of end region 1	0.44298	0.816257	3.23025	4.3784	NA
area of end region 2(mm^2)	335	89	46	9	NA
radius of end region 2(mm)	6.69183	4.88235	4.8	3.23831	NA
irregularity of end region 2	0.419947	0.84143	1.57353	3.66052	NA
qa	0.146411	0.124726	0.164339	0.251602	NA
inc_t	0.894854	0.602643	0.742176	0.816685	NA
dec_t	0.0399168	0.223773	0.07149	0.193942	NA
qa_map	0.148177	0.126486	0.166319	0.254561	NA
ICBM152_adult.T1W	174.794	172.162	186.69	168.626	NA
ICBM152_adult.WM	61.9906	50.0898	116.918	111.357	NA

Negative Correlations (FDR = 1.000000)

Not significant

Figures

Slice overlay image displaying ROIs with tracts that had RD positively correlated with loop Angular error rad3 in men

Glass Brain displaying tracts that had RD positively correlated with loop angular error rad3 in men

Women

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.000631)

V1	V2	V3	V4	V5	V6	V7	V8
Tract Name	Fornix_L	Fornix_R	Corpus_Callosum_Body	Corpus_Callosum_Tapetum	Thalamic_Radiation_Superior_L	Cingulum_Frontal_Parietal_L	NA
number of tracts	803	324	77	56	50	17	NA
mean length(mm)	56.0847	54.8724	54.1434	59.6825	53.7264	54.8275	NA
span(mm)	21.7578	23.581	20.6704	21.9326	14.5498	24.0448	NA
curl	2.57768	2.32698	2.61936	2.72118	3.69259	2.28022	NA
elongation	6.04314	8.11601	9.8456	12.3596	11.5693	35.1114	NA
diameter(mm)	9.28072	6.761	5.49924	4.82883	4.64389	1.56153	NA
volume(mm^3)	3794	1970	1286	1093	910	105	NA
trunk volume(mm^3)	3430	1495	533	134	271	70	NA
branch volume(mm^3)	364	475	753	959	639	35	NA
total surface area(mm^2)	9829	6485	6799	5771	4348	820	NA
total radius of end regions(mm)	13.357	12.9792	17.7545	31.4854	13.985	4.8142	NA
total area of end regions(mm^2)	708	331	113	83	71	17	NA
irregularity	6.01082	5.5641	7.26854	6.37401	5.54715	3.0487	NA
area of end region 1(mm^2)	350	168	53	45	35	7	NA
radius of end region 1(mm)	7.11935	7.11319	8.62274	19.4092	7.11512	2.33479	NA
irregularity of end region 1	0.454948	0.946172	4.40722	26.2998	4.54409	2.44652	NA
area of end region 2(mm^2)	358	163	60	38	36	10	NA
radius of end region 2(mm)	6.23762	5.86602	9.1318	12.0762	6.86992	2.47941	NA
irregularity of end region 2	0.341432	0.663207	4.36628	12.0566	4.11861	1.93129	NA
qa	0.154405	0.136414	0.278221	0.25252	0.167394	0.122222	NA
inc_t	0.0216797	0.0286679	0.0360744	0.0419393	0.0292107	0.00748792	NA
dec_t	1.40691	1.33244	1.33789	1.11083	1.45159	1.28391	NA
qa_map	0.156275	0.138524	0.284104	0.255761	0.169933	0.125605	NA
ICBM152_adult.T1W	169.005	147.855	177.519	164.89	177.756	198.015	NA
ICBM152_adult.WM	60.1516	35.3153	124.768	90.4514	100.88	128.423	NA

Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in women

Glass Brain displaying tracts that had RD positively and negatively correlated with loop angular error rad3 in women

pre

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.030260)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10
Tract Name	Fornix_L	Fornix_R	Corpus_Callosum_Tapetum	Corpus_Callosum_Body	Corpus_Callosum_Forceps_Major	Cerebellum_R	Thalamic_Radiation_Superior_L	Cingulum_Frontal_Parietal_L	NA
number of tracts	637	258	36	30	29	28	18	13	NA
mean length(mm)	60.8372	57.824	58.8379	63.9396	58.9119	53.5071	54.2306	52.9322	NA
span(mm)	22.4441	24.2811	22.3727	16.0202	24.9094	24.4108	11.9267	23.4392	NA
curl	2.71061	2.38145	2.62989	3.99118	2.36505	2.19194	4.547	2.25828	NA
elongation	6.91911	9.98849	14.5565	16.8163	13.8347	15.9153	17.8759	28.5402	NA
diameter(mm)	8.79263	5.78906	4.04203	3.80223	4.25828	3.36199	3.03372	1.85465	NA
volume(mm^3)	3694	1522	755	726	839	475	392	143	NA
trunk volume(mm^3)	2403	498	257	122	89	139	189	73	NA
branch volume(mm^3)	1291	1024	498	604	750	336	203	70	NA
total surface area(mm^2)	12602	6362	4439	4361	4769	3294	2602	1128	NA
total radius of end regions(mm)	18.6486	12.6007	19.5674	18.5539	12.5027	13.7018	14.2387	5.13462	NA
total area of end regions(mm^2)	552	220	54	51	42	34	29	15	NA
irregularity	7.49897	6.04961	5.94125	5.70989	6.05118	5.82863	5.03428	3.65743	NA
area of end region 1(mm^2)	284	101	27	26	21	15	14	9	NA
radius of end region 1(mm)	10.2093	6.84982	8.56332	8.56849	5.5854	6.68516	5.31325	2.18491	NA
irregularity of end region 1	1.15298	1.45944	8.5324	8.87125	4.66701	9.36014	6.33494	1.66638	NA
area of end region 2(mm^2)	268	119	27	25	21	19	15	6	NA
radius of end region 2(mm)	8.43929	5.7509	11.0041	9.98541	6.91727	7.01665	8.92541	2.94971	NA
irregularity of end region 2	0.834885	0.873121	14.0895	12.5297	7.15814	8.1406	16.6846	4.55573	NA
qa	0.169252	0.151158	0.281925	0.25991	0.274995	0.123909	0.195785	0.119879	NA
inc_t	0.0302541	0.0245192	0.0983148	0.0675797	0.210173	0.0345652	0.0552861	0.0343937	NA
dec_t	1.79158	2.47154	1.51705	1.73972	1.06367	1.51339	1.72566	1.80816	NA
qa_map	0.171595	0.153053	0.28521	0.263838	0.277901	0.125022	0.199441	0.122567	NA
ICBM152_adult.T1W	169.267	162.082	166.202	176.022	173.879	172.678	191.628	196.58	NA
ICBM152_adult.WM	60.4165	50.6869	109.101	118.57	128.857	30.6746	128.135	122.882	NA

Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in pre-menopausal women

Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3 in pre-menopausalwomen

peri

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.017967)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17	V18	V19	V20	V21
Tract Name	Corpus_Callosum_Body	Corpus_Callosum_Forceps_Major	Corpus_Callosum_Tapetum	Fornix_L	Cerebellum_R	Corpus_Callosum_Forceps_Minor	Cerebellum_L	Fornix_R	Inferior_Longitudinal_Fasciculus_R	Thalamic_Radiation_Posterior_R	Corticostriatal_Tract_Posterior_R	Dentatorubrothalamic_Tract_L	Arcuate_Fasciculus_R	Thalamic_Radiation_Superior_L	Middle_Cerebellar_Peduncle	Reticular_Tract_R	Reticular_Tract_L	Cingulum_Parolfactory_R	Corticospinal_Tract_L	NA
number of tracts	128	102	98	94	68	63	52	26	25	22	19	19	16	15	14	13	12	10	10	NA
mean length(mm)	60.2305	60.6943	61.7859	62.3784	54.0638	57.4765	53.2363	59.4028	60.0235	54.6439	53.2758	57.056	55.5145	63.0769	60.8666	57.087	62.4961	65.8215	57.4239	NA
span(mm)	21.9182	23.7235	23.7322	20.9358	25.0929	21.1464	24.5342	25.0968	25.5671	25.244	22.8764	25.0887	21.6387	19.8764	22.4672	23.8772	25.9041	30.6326	27.955	NA
curl	2.74796	2.5584	2.60347	2.97951	2.15454	2.71803	2.16988	2.36694	2.34769	2.16463	2.32885	2.27417	2.56552	3.17346	2.70913	2.39086	2.4126	2.14874	2.05415	NA
elongation	6.12991	6.64491	7.54752	9.52541	7.01647	7.74827	7.54064	17.2075	11.7942	11.4177	10.8064	13.7286	13.1252	17.2292	16.2705	17.6133	19.1458	30.9377	21.0385	NA
diameter(mm)	9.82567	9.13395	8.18626	6.54864	7.70528	7.41798	7.05992	3.45215	5.08923	4.78587	4.93004	4.15599	4.2296	3.66104	3.74092	3.24113	3.26422	2.12755	2.72947	NA
volume(mm^3)	4567	3977	3252	2101	2521	2484	2084	556	1221	983	1017	774	780	664	669	471	523	234	336	NA
trunk volume(mm^3)	0	0	108	107	180	0	0	86	0	0	62	113	64	0	64	73	0	93	0	NA
branch volume(mm^3)	4567	3977	3144	1994	2341	2484	2084	470	1221	983	955	661	716	664	605	398	523	141	336	NA
total surface area(mm^2)	31708	22905	20361	9712	14805	14030	11398	3114	8173	6796	7273	5540	5205	4583	5029	2870	3496	1775	2632	NA
total radius of end regions(mm)	39.2324	30.1747	39.6365	17.3276	17.3715	21.6114	10.7249	10.1279	25.071	18.982	17.3667	47.4258	18.4517	19.4574	20.8431	21.9931	42.189	13.5979	12.3994	NA
total area of end regions(mm^2)	210	175	151	126	106	104	87	35	45	40	37	31	30	25	25	21	18	15	18	NA
irregularity	17.0545	13.1514	12.8137	7.56787	11.3126	10.4745	9.65319	4.83363	8.51644	8.27182	8.81421	7.43676	7.05611	6.31722	7.0303	4.93739	5.45493	4.03461	5.34521	NA
area of end region 1(mm^2)	105	90	75	69	49	53	42	19	23	19	19	16	15	14	12	9	9	6	10	NA
radius of end region 1(mm)	18.0721	19.3852	25.1322	10.9873	7.03918	11.2517	4.64161	4.88337	12.5748	9.642	10.3605	27.4742	8.138	12.9941	8.82004	12.7431	25.0791	6.06787	4.67343	NA
irregularity of end region 1	9.77191	13.1175	26.4576	5.49649	3.17686	7.50428	1.61153	3.94308	21.5986	15.372	17.7484	148.211	13.8706	37.8892	20.3662	56.6834	219.549	19.2784	6.86153	NA
area of end region 2(mm^2)	105	85	76	57	57	51	45	16	22	21	18	15	15	11	13	12	9	9	8	NA
radius of end region 2(mm)	21.1603	10.7895	14.5042	6.34026	10.3323	10.3597	6.08324	5.2445	12.4962	9.34001	7.00617	19.9516	10.3137	6.46332	12.023	9.24998	17.1099	7.53001	7.72593	NA
irregularity of end region 2	13.3969	4.3026	8.69611	2.21559	5.88398	6.61116	2.58349	5.40055	22.2989	13.0504	8.56719	83.371	22.2786	11.9308	34.933	22.4001	102.188	19.7924	23.4402	NA
qa	0.263052	0.285966	0.253793	0.152229	0.113225	0.241646	0.126245	0.144512	0.232488	0.226512	0.202426	0.24162	0.224804	0.158737	0.221471	0.172261	0.17946	0.176172	0.297009	NA
inc_t	0.157746	0.194091	0.149995	0.151021	0.22574	0.236622	0.397456	0.208797	0.213121	0.207203	0.205429	0.256298	0.182706	0.0731557	0.367053	0.201515	0.32213	0.263596	0.250786	NA
dec_t	1.2437	1.02577	1.11665	1.04612	1.17011	1.13634	0.786282	0.716828	0.980037	0.96233	1.05725	0.858782	1.01517	1.06153	0.773196	0.965973	0.827268	0.763737	0.97458	NA
qa_map	0.268414	0.289726	0.257294	0.154285	0.114205	0.245553	0.127598	0.146382	0.236634	0.230647	0.205934	0.243815	0.227658	0.161836	0.227396	0.174315	0.181617	0.186053	0.299365	NA
ICBM152_adult.T1W	198.016	205.917	179.983	175.385	175.219	219.549	161.21	148.074	223.317	220.399	219.397	197.159	226.499	184.913	215.801	163.96	163.308	174.226	213.007	NA
ICBM152_adult.WM	188.693	207.294	139.073	73.4995	49.8151	235.947	20.4462	35.9977	249.029	235.689	232.694	161.576	250.869	111.683	233.779	77.7218	77.2735	82.2829	236.724	NA

Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in perimenopausal women

Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3 in peri menopausal women

post

Positive Correlations (FDR = 1.000000) No Significant Findings

Negative Correlations (FDR = 0.273451)

No Significant Findings

Peri + Post

Positive Correlations (FDR = 1.000000)

No significant

Negative Correlations (FDR = 0.231903)

No significant

Loop Angular error average

QA

All subjects

Positive Correlations (FDR = 0.001274)

.
Corpus_Callosum_Forceps_Minor
526
54.6692
10.5963
4821

Negative Correlations (FDR= 0.009901)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corticospinal_Tract_R	103	54.0583	6.05964	1559
Corpus_Callosum_Forceps_Major	30	56.5333	4.0603	732
Cerebellum_R	24	52.5	3.76985	586
Medial_Lemniscus_R	20	55	3.50607	531
Arcuate_Fasciculus_L	15	53.6	3.57158	537
Cingulum_Frontal_Parietal_L	12	52.6667	2.36316	231

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular Error average

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop Angular Error average

Glass Brain displaying tracts that had QA positively and negatively correlated with loop Angular Error average

Men

Positive Correlations (FDR =0.249739)

not significant

Negative Correlations (FDR =0.038326)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Cerebellum_L	897	53.5295	15.2894	9828
Corpus_Callosum_Forceps_Major	330	59.697	8.26011	3199
Cerebellum_R	263	53.3308	9.28881	3614
Corpus_Callosum_Tapetum	77	58.9091	5.70148	1504
Vermis	64	52.7812	5.23716	1137
Arcuate_Fasciculus_L	26	57.6154	4.27761	828
Cingulum_Frontal_Parietal_R	6	53.6667	2.1783	200

Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average

Glass Brain displaying tracts that had QA negatively correlated with loop angular error average

Women

Positive Correlations (FDR =0.009950)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	62	52.3548	6.58864	1785
Cerebellum_L	57	53.9298	4.75083	956
Corpus_Callosum_Forceps_Major	25	55.2	3.92237	667

Negative Correlations (FDR = 0.001003)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corticospinal_Tract_R	611	56.3011	10.0261	4445
Medial_Lemniscus_R	278	57.0647	7.33297	2410
Corticostriatal_Tract_Superior_R	61	53.9344	5.36443	1219
Dentatorubrothalamic_Tract_R	55	52.2545	5.39606	1195
Cingulum_Frontal_Parietal_L	44	53.5455	3.36432	476
Corpus_Callosum_Tapetum	43	52.5581	5.31477	1166
Arcuate_Fasciculus_R	37	54.3784	3.81011	620
Corticospinal_Tract_L	29	56	4.65243	952
Corpus_Callosum_Body	29	54.8276	4.91678	1041
Corpus_Callosum_Forceps_Major	29	55.8621	3.74703	616
Extreme_Capsule_R	21	54.8571	2.88257	358
Inferior_Fronto_Occipital_Fasciculus_L	12	52.1667	2.62816	283
Extreme_Capsule_L	10	53.2	2.58868	280

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop angular error average

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average

pre

Positive Correlations (FDR = 0.057417)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Major	771	62.4971	11.3668	6342
Corpus_Callosum_Tapetum	478	54.7222	11.6298	5813
Corpus_Callosum_Body	402	60.5216	9.15962	3988
Cerebellum_L	302	56.325	8.817	3439
Corpus_Callosum_Forceps_Minor	169	58.1751	6.87565	2160
Fornix_L	82	56.7185	4.75689	1008
Inferior_Longitudinal_Fasciculus_L	73	58.3937	6.6792	2046
Arcuate_Fasciculus_L	61	54.697	3.93741	666
Inferior_Fronto_Occipital_Fasciculus_L	47	54.697	5.81576	1453
Fornix_R	35	53.7272	3.21809	437
Corticostriatal_Tract_Posterior_L	24	52.5179	4.4939	833
Inferior_Longitudinal_Fasciculus_R	15	52.2904	3.35764	463
Thalamic_Radiation_Posterior_L	12	52.3479	3.08385	391
Cerebellum_R	11	57.0929	2.82162	357

Negative Correlations (FDR = 0.019934)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Inferior_Fronto_Occipital_Fasciculus_R	597	69.1472	10.6277	6134
Middle_Cerebellar_Peduncle	351	59.2899	11.2905	5936
Corticospinal_Tract_L	332	59.9263	11.7028	6446
Corticospinal_Tract_R	325	63.6286	9.38223	4399
Cerebellum_L	218	56.8343	8.17616	2984
Inferior_Fronto_Occipital_Fasciculus_L	205	60.002	7.07666	2360
Corpus_Callosum_Tapetum	170	64.3293	8.57492	3715
Corticostriatal_Tract_Superior_L	153	56.2031	8.85602	3462
Cingulum_Frontal_Parietal_L	150	57.1294	6.42112	1850
Arcuate_Fasciculus_R	132	65.6466	7.61398	2989
Cingulum_Frontal_Parietal_R	128	58.7267	7.0462	2290
Corpus_Callosum_Body	124	61.256	8.95492	3858
Medial_Lemniscus_L	117	59.0155	6.94246	2234
Vermis	93	54.8679	6.50948	1826
Dentatorubrothalamic_Tract_L	88	58.6704	7.99852	2948
Cingulum_Parolfactory_R	83	65.7486	4.14685	888
Inferior_Longitudinal_Fasciculus_R	83	60.2585	6.47302	1983
Medial_Lemniscus_R	80	57.9821	6.59054	1978
Dentatorubrothalamic_Tract_R	79	62.4662	7.14556	2505
Superior_Longitudinal_Fasciculus2_R	76	56.1198	6.58112	1909
Arcuate_Fasciculus_L	70	61.0098	4.92234	1161
Superior_Longitudinal_Fasciculus2_L	56	56.6153	5.97228	1586
Uncinate_Fasciculus_R	54	55.2688	4.38327	834
Corticopontine_Tract_Parietal_L	49	69.6075	4.75484	1236
Corpus_Callosum_Forceps_Major	33	60.6761	4.62643	1020
Corticopontine_Tract_Parietal_R	28	64.2252	4.91793	1220
Frontal_Aslant_Tract_L	24	66.2587	4.96338	1282
Extreme_Capsule_L	22	60.2918	4.26162	860
Uncinate_Fasciculus_L	18	60.2331	2.94035	409
Cingulum_Frontal_Parahippocampal_L	17	55.0528	3.47457	522
Superior_Longitudinal_Fasciculus1_R	17	52.5971	3.07654	391
Corticostriatal_Tract_Superior_R	13	57.0858	3.64292	595
Cingulum_Frontal_Parahippocampal_R	12	56.3262	3.02944	406
Reticular_Tract_R	10	59.6128	2.27349	242

Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop angular error average

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average

peri

Positive Correlations (FDR =0.530855)

Not significant

Negative Correlations (FDR = 0.010149)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Body	317	65.6593	15.7849	12849
Cerebellum_L	260	55.7538	14.3523	9020
Corpus_Callosum_Tapetum	213	63.8592	12.3744	7680
Inferior_Fronto_Occipital_Fasciculus_R	199	63.4271	10.7688	5777
Middle_Cerebellar_Peduncle	183	61.5956	12.0152	6984
Cerebellum_R	178	54.573	13.2554	7531
Corpus_Callosum_Forceps_Major	176	61.0909	11.5367	6386
Arcuate_Fasciculus_R	169	68.5562	9.87911	5255
Superior_Longitudinal_Fasciculus2_R	160	64.6	10.2543	5335
Corticospinal_Tract_R	139	65.7698	9.72465	4885
Cingulum_Frontal_Parietal_R	123	65.8211	7.8443	3181
Arcuate_Fasciculus_L	121	58.1322	10.468	5003
Corticostriatal_Tract_Posterior_R	113	65.4513	9.08837	4246
Inferior_Longitudinal_Fasciculus_L	96	61.7292	8.74894	3711
Inferior_Longitudinal_Fasciculus_R	90	61.2889	9.43715	4287
Inferior_Fronto_Occipital_Fasciculus_L	85	63.3882	8.40976	3521
Dentatorubrothalamic_Tract_R	79	59.9494	9.3849	4147
Medial_Lemniscus_R	77	64.1299	7.57878	2893
Superior_Longitudinal_Fasciculus2_L	76	60.2895	8.54692	3459
Corticostriatal_Tract_Posterior_L	70	62.2286	8.46966	3506
Frontal_Aslant_Tract_L	64	60.6562	7.9316	2997
Dentatorubrothalamic_Tract_L	63	58.4762	8.37584	3222
Corticostriatal_Tract_Superior_L	58	56.6207	7.71078	2644
Medial_Lemniscus_L	58	58.2069	6.57448	1976
Corticospinal_Tract_L	56	60.6786	7.35636	2579
Cingulum_Frontal_Parietal_L	53	60.7547	6.39595	1952
Corticopontine_Tract_Parietal_R	50	61.92	6.65368	2153
Thalamic_Radiation_Posterior_R	50	61.32	6.51311	2043
Vermis	49	55.3469	6.68739	1944
Corpus_Callosum_Forceps_Minor	44	57.3636	7.05746	2244
Cingulum_Parahippocampal_Parietal_R	37	57.2432	5.45329	1337
Corticostriatal_Tract_Superior_R	36	61.3889	6.49669	2035
Superior_Longitudinal_Fasciculus1_R	32	66.9375	5.18248	1412
Optic_Radiation_L	30	55.3333	4.90834	1047
Anterior_Commissure	30	65.6667	5.1521	1369
Corticopontine_Tract_Parietal_L	29	68.6897	5.50514	1635
Extreme_Capsule_R	27	63.1852	5.15549	1319
Thalamic_Radiation_Anterior_R	26	63.5385	4.99082	1243
Cingulum_Parolfactory_R	25	67.36	4.19497	931
Superior_Longitudinal_Fasciculus3_R	23	61.6522	4.78356	1108
Extreme_Capsule_L	22	60.2727	4.80293	1092
Thalamic_Radiation_Posterior_L	20	56.2	5.21842	1202
Parietal_Aslant_Tract_L	19	57.0526	4.80836	1036
Reticular_Tract_R	19	63.4737	4.88986	1192
Middle_Longitudinal_Fasciculus_R	18	58.3333	4.61789	977
Superior_Longitudinal_Fasciculus3_L	18	57.5556	4.45955	899
Parietal_Aslant_Tract_R	15	55.4667	3.88939	659
Corticopontine_Tract_Frontal_R	15	60.8	4.70924	1059
Corticopontine_Tract_Occipital_R	13	64.4615	3.38177	579
Thalamic_Radiation_Superior_R	13	61.3846	4.28931	887
Frontal_Aslant_Tract_R	12	53.3333	3.92406	645
Fornix_R	12	69.8333	3.07318	518
Middle_Longitudinal_Fasciculus_L	11	55.8182	3.80287	634
Reticular_Tract_L	10	60.4	3.75254	668

Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average

post

Positive Correlations (FDR= 1.000000)

Negative Correlations (FDR =0.129906)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Body	2830	69.711	27.605	41722
Corpus_Callosum_Forceps_Minor	1108	68.9404	17.8293	17212
Corpus_Callosum_Forceps_Major	1068	78.3296	16.4186	16584
Arcuate_Fasciculus_L	790	71.4228	15.1864	12937
Corpus_Callosum_Tapetum	637	67.0769	16.063	13593
Cerebellum_R	536	57.6604	17.0805	13212
Corticospinal_Tract_R	383	65.0653	11.6721	6962
Inferior_Longitudinal_Fasciculus_L	284	68.6127	11.8624	7583
Inferior_Fronto_Occipital_Fasciculus_L	273	71.6337	11.4686	7400
Superior_Longitudinal_Fasciculus2_L	270	62.6889	12.4429	7623
Cingulum_Frontal_Parietal_L	264	69.7879	9.97979	5459
Middle_Cerebellar_Peduncle	263	60.4411	12.9273	7933
Inferior_Fronto_Occipital_Fasciculus_R	257	70.5214	11.2741	7040
Dentatorubrothalamic_Tract_R	231	61.6537	12.4735	7534
Cerebellum_L	220	55.3455	13.0502	7403
Medial_Lemniscus_R	219	63.8539	10.1198	5136
Corticostriatal_Tract_Posterior_L	215	67.8233	10.7772	6187
Corticospinal_Tract_L	176	62.3864	10.9854	5913
Dentatorubrothalamic_Tract_L	176	60.1364	11.8756	6661
Corticostriatal_Tract_Posterior_R	173	59.896	10.7061	5392
Cingulum_Frontal_Parietal_R	171	65.6491	9.32241	4481
Corticostriatal_Tract_Superior_L	156	58.9359	10.9647	5565
Extreme_Capsule_L	148	66.7703	8.98012	4229
Medial_Lemniscus_L	146	63.7123	9.13532	4176
Inferior_Longitudinal_Fasciculus_R	144	60.25	11.2641	6004
Superior_Longitudinal_Fasciculus2_R	144	60.7639	11.409	6212
Frontal_Aslant_Tract_L	131	64.626	10.3564	5444
Corticostriatal_Tract_Superior_R	128	58.9219	9.61024	4274
Parietal_Aslant_Tract_L	122	60.1803	7.56644	2706
Arcuate_Fasciculus_R	110	60.8727	8.92701	3810
Thalamic_Radiation_Posterior_L	106	60.5283	8.47437	3414
Middle_Longitudinal_Fasciculus_L	97	62.3918	7.7996	2981
Middle_Longitudinal_Fasciculus_R	93	64.7957	7.08145	2552
Thalamic_Radiation_Anterior_R	90	64.1778	8.57	3702
Frontal_Aslant_Tract_R	74	60.7568	8.1852	3197
Corticopontine_Tract_Parietal_R	70	66.4	6.58302	2260
Superior_Longitudinal_Fasciculus3_L	67	65.1642	7.1794	2638
Corticopontine_Tract_Parietal_L	65	65.0154	7.03059	2524
Extreme_Capsule_R	63	63.4603	6.45539	2077
Thalamic_Radiation_Posterior_R	61	62.4262	7.14071	2500
Superior_Longitudinal_Fasciculus1_L	56	63	5.97082	1764
Thalamic_Radiation_Anterior_L	53	59.6981	7.09465	2360
Superior_Longitudinal_Fasciculus3_R	50	58.88	6.82011	2151
Thalamic_Radiation_Superior_L	50	63.88	7.58571	2887
Parietal_Aslant_Tract_R	49	56.3265	6.26431	1736
Superior_Longitudinal_Fasciculus1_R	48	57.7917	5.92978	1596
Thalamic_Radiation_Superior_R	48	62.8333	6.95628	2388
Reticular_Tract_R	48	61.7917	6.83615	2268
Fornix_L	44	58.4091	6.71576	2069
Cingulum_Parolfactory_R	43	65.0233	4.77621	1165
Uncinate_Fasciculus_R	40	67.25	4.99725	1319
Reticular_Tract_L	39	59.0256	5.71476	1514
Cingulum_Parahippocampal_Parietal_R	38	61.7895	4.97058	1199
Corticostriatal_Tract_Anterior_R	35	54.4	6.3706	1734
Corticostriatal_Tract_Anterior_L	32	55	6.21773	1670
Cingulum_Frontal_Parahippocampal_L	30	69.8	5.32075	1552
Cingulum_Parolfactory_L	26	58.6154	5.13098	1212
Anterior_Commissure	26	58.3846	5.48388	1379
Superior_Cerebellar_Peduncle	26	58	4.48669	917
Cingulum_Parahippocampal_Parietal_L	24	57.4167	4.49218	910
Fornix_R	22	58.6364	3.43693	544
Cingulum_Frontal_Parahippocampal_R	16	61	3.36349	542
Corticopontine_Tract_Occipital_R	14	66	3.65109	691
Inferior_Cerebellar_Peduncle_L	14	55.2857	3.31442	477
Corticopontine_Tract_Occipital_L	12	59.5	3.53208	583
Corticopontine_Tract_Frontal_L	10	55.8	3.5329	547
Optic_Radiation_L	10	52.6	3.61542	540

Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average

Glass Brain displaying tracts that had QA negatively correlated with loop angular error average

Peri and Post

Positive Correlations (FDR =0.007092)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Forceps_Minor	226	56.0531	8.72584	3352
Middle_Cerebellar_Peduncle	43	55.5814	5.07201	1123
Inferior_Longitudinal_Fasciculus_R	19	53.0526	3.23478	436
Cingulum_Parolfactory_L	16	54.875	2.05496	182
Inferior_Fronto_Occipital_Fasciculus_R	12	52.3333	3.45978	492
Corpus_Callosum_Body	11	54.1818	3.18986	433
Cingulum_Parolfactory_R	10	54.8	1.73795	130

Negative Correlations (FDR = 0.000492)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Body	507	64.2485	13.5714	9294
Corpus_Callosum_Tapetum	192	58.7083	8.84828	3610
Corpus_Callosum_Forceps_Major	184	64.9891	8.24754	3472
Arcuate_Fasciculus_L	130	60.2923	6.99348	2316
Corticospinal_Tract_R	60	57.4667	6.11371	1687
Corpus_Callosum_Forceps_Minor	53	58.2642	5.99931	1647
Medial_Lemniscus_R	49	56.3673	5.05667	1132
Corticostriatal_Tract_Superior_R	31	53.6129	4.57153	880
Thalamic_Radiation_Posterior_L	31	54.9032	4.20372	762
Cerebellum_R	25	52.88	3.66873	559
Superior_Longitudinal_Fasciculus2_R	20	54.4	3.25974	454
Parietal_Aslant_Tract_L	17	56.8235	2.62704	308
Corticostriatal_Tract_Posterior_L	17	60.5882	4.26353	865
Cingulum_Frontal_Parietal_R	15	52.9333	3.0863	396
Cingulum_Parolfactory_L	15	55.3333	2.00095	174
Inferior_Fronto_Occipital_Fasciculus_R	14	53.8571	3.04422	392
Inferior_Longitudinal_Fasciculus_L	14	56.4286	3.12572	433
Cingulum_Parolfactory_R	13	53.5385	2.80567	331
Cerebellum_L	13	51.8461	2.94431	353
Extreme_Capsule_R	12	52.8333	3.0102	376
Extreme_Capsule_L	11	55.4545	3.31284	478
Inferior_Fronto_Occipital_Fasciculus_L	11	56	3.06062	412
Corticostriatal_Tract_Posterior_R	11	50.7273	3.3043	435

Figures

<b

Plots

MD

All subjects

Positive Correlations (FDR =0.494235)

Not Significant

Negative Correlations (FDR = 0.211694)

Not significant

Men

Positive Correlations (FDR = 0.012952)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	1963	58.0856	10.7612	5283
Fornix_R	310	55.1097	7.86733	2679
Thalamic_Radiation_Superior_L	198	55.2525	7.42592	2393
Corpus_Callosum_Forceps_Major	148	58.7297	6.05477	1691
Cerebellum_L	38	52.5263	3.67776	558
Thalamic_Radiation_Posterior_L	21	53.7143	3.92826	651
Thalamic_Radiation_Superior_R	13	55.6923	2.61453	299

Negative Correlations (FDR = 0.842857)

Not significant

Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop angular error average

Glass Brain displaying tracts that had MD positively correlated with loop angular error average

Women

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.020210)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	1745	57.9862	11.0054	5516
Fornix_R	644	56.4255	8.47093	3180
Thalamic_Radiation_Superior_L	221	56.3348	7.35578	2394
Corpus_Callosum_Tapetum	179	57.229	8.15473	2989
Corpus_Callosum_Body	130	59.4769	7.46049	2600
Cingulum_Frontal_Parietal_L	115	59.1478	4.70187	1027
Uncinate_Fasciculus_R	62	57.2903	4.3642	857
Corpus_Callosum_Forceps_Major	44	57.5454	4.02718	733
Cerebellum_R	29	51.4483	3.74925	568
Thalamic_Radiation_Superior_R	17	52.4706	3.55904	522
Thalamic_Radiation_Anterior_L	15	58.5333	2.76317	351
Optic_Radiation_L	10	52	2.26758	210

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average

Glass Brain displaying tracts that had MD negatively correlated with loop angular error average

pre

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.065391)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	786	61.5242	8.65897	3623
Fornix_R	213	57.3052	5.41968	1322
Cerebellum_R	130	55.8461	5.92734	1541
Corpus_Callosum_Forceps_Major	61	60.3934	5.0109	1191
Optic_Radiation_L	41	55.6097	4.01767	705
Thalamic_Radiation_Superior_L	30	54.2	3.27294	456
Corpus_Callosum_Tapetum	29	56.2759	4.40336	857
Cingulum_Frontal_Parietal_L	10	54.4	1.6689	119
Inferior_Fronto_Occipital_Fasciculus_L	10	58.2	2.68689	330

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average

Glass Brain displaying tracts that had MD negatively correlated with loop angular error average

peri

Positive Correlations (FDR =1.000000)

Not significant

Negative Correlations (FDR = 0.004145)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Tapetum	129	61.2093	8.94091	3843
Corpus_Callosum_Forceps_Major	119	61.563	10.0329	4867
Cerebellum_R	89	54.5843	8.37367	3006
Corpus_Callosum_Body	81	63.5556	7.97912	3178
Corticostriatal_Tract_Posterior_R	69	55.6522	7.37753	2379
Fornix_L	64	63.8438	6.07902	1853
Inferior_Longitudinal_Fasciculus_R	63	63.8095	7.46397	2792
Cerebellum_L	54	53.1481	6.38356	1701
Corpus_Callosum_Forceps_Minor	38	58.6316	6.34176	1852
Arcuate_Fasciculus_R	28	58.6429	5.04227	1171
Inferior_Fronto_Occipital_Fasciculus_R	28	59.2143	4.90082	1117
Arcuate_Fasciculus_L	26	55.4615	4.48191	875
Inferior_Fronto_Occipital_Fasciculus_L	26	60.0769	5.17986	1266
Dentatorubrothalamic_Tract_L	19	57.0526	4.44164	884
Inferior_Longitudinal_Fasciculus_L	17	59.1765	4.1824	813
Fornix_R	17	59.6471	3.1607	468
Middle_Cerebellar_Peduncle	16	63.125	3.71435	684
Dentatorubrothalamic_Tract_R	13	59.3846	3.55667	590
Anterior_Commissure	13	57.2308	3.85504	668
Thalamic_Radiation_Superior_L	12	57.1667	3.52534	558
Superior_Longitudinal_Fasciculus2_L	11	58.5454	3.41103	535
Corticospinal_Tract_L	11	53.2727	3.2539	443
Optic_Radiation_L	11	55.4545	3.61445	569
Superior_Longitudinal_Fasciculus2_R	10	56	3.57143	561
Corticostriatal_Tract_Posterior_L	10	56.4	3.30892	485

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average

Glass Brain displaying tracts that had MD negatively correlated with loop angular error average

post

Positive Correlations (FDR = 1.000000)

Not significant

Negative Correlations (FDR = 0.028462)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Cerebellum_R	145	55.4897	11.2747	5540
Fornix_L	96	58.3125	6.09792	1703
Corpus_Callosum_Tapetum	69	60.058	7.13899	2404
Corpus_Callosum_Forceps_Major	59	65.0508	7.2696	2700
Cerebellum_L	50	55.76	6.51704	1860
Arcuate_Fasciculus_L	38	54.3158	5.38489	1237
Corticostriatal_Tract_Posterior_R	38	60.3684	5.77635	1582
Superior_Longitudinal_Fasciculus2_R	31	59.871	5.84595	1607
Corpus_Callosum_Body	31	55.0323	6.28991	1710
Inferior_Longitudinal_Fasciculus_R	26	60.7692	5.54028	1465
Arcuate_Fasciculus_R	24	58	4.89837	1093
Middle_Cerebellar_Peduncle	23	59.5652	5.24503	1287
Fornix_R	22	58.8182	3.06156	433
Inferior_Fronto_Occipital_Fasciculus_R	20	55.4	4.33588	818
Thalamic_Radiation_Superior_L	16	57	3.57763	573
Inferior_Longitudinal_Fasciculus_L	13	54.1538	3.88818	643
Corticopontine_Tract_Parietal_R	13	58.6154	3.84329	680
Corpus_Callosum_Forceps_Minor	12	53.6667	3.73818	589
Corticospinal_Tract_R	11	61.4545	3.33864	538

Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average

Glass Brain displaying tracts that had MD negatively correlated with loop angular error average

Peri and Post

Positive Correlations (FDR = 0.168126)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Inferior_Longitudinal_Fasciculus_L	156	56.8205	7.68993	2639
Cerebellum_R	149	53.3691	8.28908	2880
Cerebellum_L	125	52.992	7.20739	2162
Corpus_Callosum_Tapetum	61	56.1967	6.85329	2073
Arcuate_Fasciculus_L	49	61.7959	4.7216	1082
Arcuate_Fasciculus_R	39	56.4615	3.95602	694
Fornix_L	37	56.8108	4.21842	794
Fornix_R	35	53.3143	4.51873	855
Inferior_Longitudinal_Fasciculus_R	21	55.7143	3.72141	606
Corpus_Callosum_Forceps_Major	21	54.5714	4.05859	706
Middle_Cerebellar_Peduncle	21	52.8571	3.39681	479

Negative Correlations (FDR = 0.150048)

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Tapetum	409	58.2836	9.84303	4435
Fornix_L	392	55.7041	8.13459	2895
Cerebellum_R	176	55.125	7.46706	2414
Thalamic_Radiation_Superior_L	72	58.0556	4.92728	1107
Corpus_Callosum_Body	48	62.7917	5.15788	1312
Corpus_Callosum_Forceps_Major	29	54.3448	4.07567	709
Optic_Radiation_L	28	54.7143	3.70536	590
Inferior_Fronto_Occipital_Fasciculus_L	16	55.125	3.06227	406
Fornix_R	16	51	3.58918	516

Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop angular error average

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average

Glass Brain displaying tracts that had MD positively and negatively correlated with loop angular error average

Plots

## [1] "Fornix_L"

## [1] "Fornix_R"

## [1] "Thalamic_Radiation_Superior_L"

## [1] "Corpus_Callosum_Forceps_Major"

## [1] "Thalamic_Radiation_Superior_R"

AD

All subjects

Positive Correlations (FDR =0.414365)

Not significant

Negative Correlations (FDR =0.170648)

V1	V2	V3	V4
Tract Name	Fornix_R	Fornix_L	NA
number of tracts	258	55	NA
mean length(mm)	56.2403	54.5455	NA
span(mm)	24.8933	23.2416	NA
curl	2.25925	2.34689	NA
elongation	10.7766	13.2591	NA
diameter(mm)	5.21872	4.11382	NA
volume(mm^3)	1203	725	NA
trunk volume(mm^3)	934	487	NA
branch volume(mm^3)	269	238	NA
total surface area(mm^2)	3746	3005	NA
total radius of end regions(mm)	8.96946	9.49018	NA
total area of end regions(mm^2)	260	85	NA
irregularity	4.06262	4.26276	NA
area of end region 1(mm^2)	134	45	NA
radius of end region 1(mm)	4.19124	5.24361	NA
irregularity of end region 1	0.411841	1.91955	NA
area of end region 2(mm^2)	126	40	NA
radius of end region 2(mm)	4.77822	4.24657	NA
irregularity of end region 2	0.569261	1.41634	NA
qa	0.139811	0.156539	NA
nqa	0.214807	0.240508	NA
gfa	0.085904	0.0920635	NA
iso	0.34444	0.365729	NA
dec_t	0.847703	0.843335	NA
inc_t	0.0329109	0.0290024	NA
ICBM152_adult.T1W	140.576	157.367	NA
ICBM152_adult.WM	33.0179	57.965	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.7214	1.51774	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	2.26025	2.28643	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.8732	1.81636	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.63839	1.56076	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	2.01496	2.04605	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	2.06103	1.90457	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	2.1793	2.26002	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.7135	1.64242	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.6594	1.54425	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	2.05707	1.65941	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.59434	1.45628	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	2.13418	1.73201	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	2.16287	1.74275	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	2.30758	2.12842	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.69603	1.62997	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	2.12856	1.7858	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.59043	1.43764	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	2.07493	1.81346	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.92869	1.81667	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	2.21783	2.23197	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.97472	1.88948	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	2.07906	1.84259	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	2.25307	2.03704	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.74078	1.45489	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	2.00664	1.77758	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	2.29225	2.07755	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	2.06865	1.42248	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	2.21017	1.79536	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.63538	1.49155	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.97618	1.85006	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.83374	1.70758	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	2.09145	1.75342	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	2.02717	1.85385	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.68992	1.55069	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	2.06634	1.52114	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.98374	1.6918	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	2.23675	2.22661	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	2.05145	1.73841	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	2.30366	2.13696	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.9987	1.80867	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.83602	1.64627	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.53399	1.43204	NA

Figures

Men

Positive Correlations (FDR =0.0033520)

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11
Tract Name	Fornix_L	Fornix_R	Thalamic_Radiation_Superior_L	Corpus_Callosum_Forceps_Major	Cerebellum_L	Cingulum_Frontal_Parietal_L	Thalamic_Radiation_Posterior_L	Thalamic_Radiation_Anterior_L	Thalamic_Radiation_Superior_R	NA
number of tracts	2073	519	472	182	104	85	50	25	11	NA
mean length(mm)	56.6097	55.0096	55.8263	55.4506	52.1538	59.6706	54	52.32	54.3636	NA
span(mm)	20.5789	21.6361	18.5888	22.4224	23.7273	25.8152	15.8776	25.1333	17.983	NA
curl	2.75086	2.54249	3.00322	2.473	2.19805	2.31146	3.40102	2.0817	3.02306	NA
elongation	5.09489	6.0746	6.32198	9.24715	9.76682	11.724	10.8476	15.4374	16.6901	NA
diameter(mm)	11.1111	9.05568	8.8305	5.9965	5.3399	5.08961	4.97805	3.38916	3.25724	NA
volume(mm^3)	5489	3543	3419	1566	1168	1214	1051	472	453	NA
trunk volume(mm^3)	4324	3247	2809	1275	1121	550	385	378	62	NA
branch volume(mm^3)	1165	296	610	291	47	664	666	94	391	NA
total surface area(mm^2)	11064	8426	9115	4123	3107	4000	3786	1861	2399	NA
total radius of end regions(mm)	14.4665	9.91991	11.1753	7.93851	5.96403	8.75045	6.55391	4.30815	5.94479	NA
total area of end regions(mm^2)	1356	561	529	184	148	118	85	42	21	NA
irregularity	5.59906	5.38408	5.88549	3.94693	3.55117	4.19243	4.48309	3.34069	4.31243	NA
area of end region 1(mm^2)	806	302	279	74	72	62	47	21	10	NA
radius of end region 1(mm)	8.36351	4.89025	5.79795	3.42923	3.12727	3.56612	3.68417	2.19183	2.50496	NA
irregularity of end region 1	0.272641	0.248774	0.378525	0.499242	0.426725	0.644393	0.907258	0.718697	1.9713	NA
area of end region 2(mm^2)	550	259	250	110	76	56	38	21	11	NA
radius of end region 2(mm)	6.10296	5.02966	5.37734	4.50928	2.83676	5.18433	2.86975	2.11632	3.43983	NA
irregularity of end region 2	0.212749	0.306851	0.363366	0.580728	0.332646	1.50781	0.680853	0.670028	3.37933	NA
qa	0.144672	0.120799	0.166695	0.215384	0.114369	0.13334	0.178445	0.112089	0.154195	NA
nqa	0.222275	0.185597	0.256112	0.330918	0.175718	0.204866	0.274166	0.172214	0.236907	NA
gfa	0.0792916	0.0704748	0.0840559	0.0934985	0.0375195	0.064991	0.0874217	0.0577302	0.0803539	NA
iso	0.3962	0.380806	0.421602	0.491852	0.725243	0.447415	0.431999	0.438454	0.409048	NA
dec_t	0.0672563	0.182092	0.0524579	0.0874555	0.0376331	0.0765191	0.0416243	0.0515352	0.106437	NA
inc_t	0.838802	0.442538	0.925306	0.780237	1.40182	0.705452	1.13458	0.672231	0.705644	NA
ICBM152_adult.T1W	179.475	173.52	192.959	177.989	174.272	193.728	195.48	190.347	198.551	NA
ICBM152_adult.WM	72.173	56.2382	127.043	132.374	23.8481	113.366	132.008	102.374	130.546	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.0712	1.11587	1.01477	1.4158	1.03776	0.99167	1.08675	0.980559	0.993983	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.9336	1.80969	1.8546	2.01597	1.10431	2.06104	1.91674	2.20515	1.72282	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.22609	1.17807	1.09441	1.38529	0.941077	1.06587	1.1187	1.07307	1.00378	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.1111	1.09781	0.997237	1.27556	0.785999	0.986329	0.996197	0.978182	1.00353	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.38824	1.24122	1.31034	1.33105	0.878736	1.26151	1.30568	1.25215	1.06906	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.2653	1.15895	1.15436	1.24721	0.930617	1.14352	1.19061	1.16091	1.00339	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	1.96103	1.77278	1.94926	1.48472	1.04893	1.7999	1.8441	1.7919	1.75869	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.15065	1.11851	1.07451	1.25746	0.906912	1.04424	1.10346	1.01771	1.01545	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.14067	1.05609	1.07656	1.25654	1.11494	1.06009	1.08454	1.02853	1.03755	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.15635	1.21594	1.11117	1.2295	0.916022	1.08478	1.14256	1.08045	1.09866	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.15427	1.05988	1.13879	1.23231	0.997248	1.03839	1.08043	1.05883	0.946578	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.24266	1.3377	1.29904	1.43572	0.943268	1.37382	1.31908	1.3787	1.22264	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.19663	1.39485	1.09866	1.41356	0.94359	1.05054	1.15175	1.05436	1.11062	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.49784	1.56477	1.45104	1.47191	1.1173	1.32117	1.46127	1.27584	1.32857	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.11509	1.12068	1.07173	1.38416	0.92033	1.08115	1.09199	1.04709	1.06156	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.24678	1.32863	1.22386	1.25103	1.18916	1.324	1.20442	1.37143	1.20742	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.12655	1.0908	1.02614	1.26115	0.920489	0.941721	1.06975	0.939893	0.985566	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.34676	1.3529	1.36883	1.37646	1.28866	1.22961	1.33272	1.2029	1.2235	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.26505	1.27963	1.27222	1.761	0.87272	1.43076	1.20998	1.47676	1.22711	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	1.75745	1.53116	1.65704	1.49922	0.986637	1.60668	1.57512	1.68088	1.31443	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.20894	1.11924	1.16449	1.40676	0.954399	1.15888	1.15266	1.19604	0.989729	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.24832	1.313	1.20863	1.47223	0.81432	1.24381	1.20218	1.23378	1.10969	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.62496	1.73921	1.58725	1.22093	1.09367	1.33721	1.54457	1.2736	1.59056	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.10687	1.10012	1.03284	1.30674	0.984001	1.07084	1.0365	1.08627	0.982241	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.19486	1.19914	1.14431	1.1994	0.965197	1.13141	1.16965	1.06496	1.05975	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.46706	1.54699	1.40485	1.37942	0.93584	1.40099	1.33852	1.41447	1.36523	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.1101	1.27718	1.07868	1.36436	0.87958	1.12649	1.076	1.07205	1.14483	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.47521	1.67159	1.42462	1.5882	0.880902	1.37531	1.45845	1.39322	1.45266	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.14375	1.06286	1.08207	1.39948	1.08424	1.03087	1.1293	1.04175	1.02459	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.32559	1.3025	1.16968	1.22227	0.828092	1.19534	1.14799	1.23013	1.13961	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.20129	1.16065	1.1493	1.33036	0.973418	1.14294	1.17788	1.11934	1.0767	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.22189	1.40968	1.14875	1.23401	0.873207	1.07693	1.16425	1.07859	1.10124	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.30709	1.27194	1.27928	1.39697	1.1221	1.17139	1.29027	1.15396	1.16149	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.13213	1.08287	1.11929	1.35145	0.920245	1.00474	1.13428	0.992351	1.02456	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.16512	1.3027	1.12331	1.34127	0.811239	0.996001	1.13527	0.991167	1.11134	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.20955	1.32233	1.16156	1.26385	1.04544	1.09894	1.19992	1.05921	1.20022	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	2.14792	2.09676	2.10406	2.14873	1.28413	2.13007	2.15585	2.2091	1.94801	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.15004	1.19128	1.06952	1.26946	1.05517	1.01754	1.0812	0.995945	1.0123	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	1.70987	1.72785	1.72003	1.59988	0.898706	1.85571	1.63014	1.99083	1.56691	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.33293	1.3348	1.23603	1.34482	1.01551	1.18955	1.21109	1.15367	1.18164	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.13373	1.14474	1.02571	1.38229	0.89964	1.03276	1.04326	1.01477	1.00265	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.15659	1.13487	1.17543	1.49471	1.07045	1.16982	1.22189	1.1566	1.12615	NA

Negative Correlations (FDR =1.000000)

Women

Positive Correlations (FDR = )

V1	V2	V3	V4
Tract Name	Cerebellum_R	Cerebellum_L	NA
number of tracts	24	13	NA
mean length(mm)	52.0833	54	NA
span(mm)	24.7233	24.9969	NA
curl	2.10665	2.16026	NA
elongation	16.1966	17.1393	NA
diameter(mm)	3.2157	3.15064	NA
volume(mm^3)	423	421	NA
trunk volume(mm^3)	394	0	NA
branch volume(mm^3)	29	421	NA
total surface area(mm^2)	1691	2519	NA
total radius of end regions(mm)	2.91898	7.4443	NA
total area of end regions(mm^2)	30	19	NA
irregularity	3.2138	4.71287	NA
area of end region 1(mm^2)	17	10	NA
radius of end region 1(mm)	1.33241	3.1006	NA
irregularity of end region 1	0.328077	3.02023	NA
area of end region 2(mm^2)	13	9	NA
radius of end region 2(mm)	1.58657	4.34371	NA
irregularity of end region 2	0.608311	6.5861	NA
qa	0.116766	0.119597	NA
nqa	0.179401	0.18375	NA
gfa	0.039757	0.0399798	NA
iso	0.647932	0.700178	NA
dec_t	0.252948	0.129667	NA
inc_t	0.395081	0.723857	NA
ICBM152_adult.T1W	158.892	141.756	NA
ICBM152_adult.WM	20.3144	8.28096	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.25451	1.23074	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.29586	0.997941	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	0.899762	0.985351	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.08338	0.93451	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	0.876574	1.04776	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.26307	1.11976	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	1.51827	1.26383	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.20549	1.38281	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.1081	1.1229	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.00941	0.907047	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	0.948671	1.13049	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.24006	1.07067	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	0.987838	1.04837	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.48736	1.10719	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.06595	1.00104	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.56057	1.51112	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.67971	1.15646	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.25305	1.43074	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	0.958568	0.978476	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	1.02607	1.13138	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.22179	1.01962	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.1504	0.948938	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.23749	1.0504	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.24654	0.927987	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	0.967482	0.951621	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.13363	1.24969	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.14385	1.04686	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	0.893614	1.06038	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	0.932182	1.14689	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.05343	1.03698	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.07078	0.989572	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.18365	1.11873	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	0.976655	1.1852	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.05363	0.968174	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	0.902692	0.936381	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.26277	1.1246	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	0.887391	1.12344	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	0.913302	1.11096	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	0.881927	1.03906	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.60521	1.1763	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.00536	1.04093	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.2685	1.35052	NA

Negative Correlations (FDR = )

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10
Tract Name	Fornix_L	Fornix_R	Thalamic_Radiation_Superior_L	Cingulum_Frontal_Parietal_L	Optic_Radiation_L	Cerebellum_R	Inferior_Fronto_Occipital_Fasciculus_L	Thalamic_Radiation_Anterior_L	NA
number of tracts	853	182	167	87	27	18	14	12	NA
mean length(mm)	55.6764	54.1758	55.3054	58.8966	55.7778	51.5555	53.7143	56.5	NA
span(mm)	22.8501	24.0784	17.9861	25.6409	26.963	24.8634	25.9586	25.4463	NA
curl	2.4366	2.24998	3.0749	2.29697	2.06868	2.07355	2.06923	2.22036	NA
elongation	6.38781	9.12751	8.05633	12.7246	17.4616	17.4364	17.1674	20.6561	NA
diameter(mm)	8.71604	5.93544	6.86484	4.62857	3.19432	2.95678	3.12885	2.73527	NA
volume(mm^3)	3322	1499	2047	991	447	354	413	332	NA
trunk volume(mm^3)	2713	1176	860	543	266	354	157	105	NA
branch volume(mm^3)	609	323	1187	448	181	0	256	227	NA
total surface area(mm^2)	8766	5231	6944	3976	1898	1578	2284	1844	NA
total radius of end regions(mm)	12.5643	8.70641	15.4934	7.91916	4.69117	3.26864	6.86511	6.3616	NA
total area of end regions(mm^2)	779	208	226	123	36	29	25	23	NA
irregularity	5.74991	5.17817	5.82186	4.64258	3.39084	3.29506	4.32585	3.79807	NA
area of end region 1(mm^2)	389	90	133	60	16	15	12	11	NA
radius of end region 1(mm)	6.38153	4.06642	7.43752	3.01922	1.7234	1.71272	3.12105	2.55992	NA
irregularity of end region 1	0.32889	0.577208	1.30664	0.477295	0.583179	0.614375	2.55018	1.87159	NA
area of end region 2(mm^2)	390	118	93	63	20	14	13	12	NA
radius of end region 2(mm)	6.1828	4.63999	8.05591	4.89994	2.96777	1.55592	3.74406	3.80168	NA
irregularity of end region 2	0.307933	0.573194	2.19228	1.19727	1.3835	0.543244	3.3876	3.78372	NA
qa	0.152304	0.143521	0.158462	0.118654	0.253276	0.114273	0.241524	0.107836	NA
nqa	0.234002	0.220507	0.243462	0.182301	0.389137	0.175571	0.37108	0.16568	NA
gfa	0.0874158	0.0848453	0.0791854	0.0587555	0.110141	0.0376683	0.106485	0.0544182	NA
iso	0.378304	0.359332	0.422244	0.446795	0.485475	0.715224	0.483482	0.449001	NA
dec_t	1.10219	0.71461	0.838796	0.785418	0.910068	0.768815	0.821057	0.616299	NA
inc_t	0.0464779	0.117264	0.0356806	0.0421295	0.0914356	0.0587694	0.0844156	0.077825	NA
ICBM152_adult.T1W	165.102	158.789	179.705	193.593	199.766	186.553	196.554	192.994	NA
ICBM152_adult.WM	60.156	54.7371	104.001	104.853	183.048	79.5257	174.687	96.041	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.41881	1.54669	1.0519	1.06524	1.41629	1.3216	1.42571	1.04344	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	2.25489	2.25112	2.0466	2.18747	1.81303	0.83578	1.87789	2.20866	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.66244	1.65128	1.27207	1.10058	1.31064	1.15028	1.28375	1.06255	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.41327	1.38616	1.04495	1.04064	1.23332	0.900686	1.22072	1.019	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.87325	1.76385	1.49552	1.37079	1.16416	1.0088	1.19289	1.27933	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.71271	1.77436	1.32769	1.23022	1.16087	0.811346	1.16449	1.16137	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	2.16422	2.11565	1.99299	1.93242	1.45836	0.864423	1.43868	1.9437	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.50996	1.48228	1.16831	1.09278	1.18455	0.832566	1.22698	1.10573	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.44085	1.50271	1.12186	1.14762	1.31184	0.906587	1.2844	1.15726	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.49891	1.8013	1.24504	1.08155	1.2295	0.848103	1.28943	1.00945	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.34478	1.37107	1.25972	1.0309	1.20482	0.749862	1.221	0.982992	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.62094	1.95448	1.49171	1.5217	1.35614	0.900831	1.36038	1.46189	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.59783	1.9796	1.17117	1.11123	1.41278	0.855255	1.36649	1.11934	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.96869	2.19325	1.64318	1.32164	1.37393	0.904326	1.34418	1.21134	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.51943	1.61421	1.1974	1.10369	1.44413	1.07171	1.41171	1.05584	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.64273	1.93858	1.39032	1.49901	1.23009	1.05317	1.22874	1.47887	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.34692	1.39236	1.0118	0.96342	1.15274	0.963098	1.19583	0.956028	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.669	1.84946	1.52768	1.29321	1.3533	0.989774	1.33871	1.23221	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.66522	1.67163	1.55221	1.59083	1.62342	0.78324	1.69349	1.52366	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	2.12436	2.04973	1.77824	1.77796	1.3751	0.959782	1.44269	1.7392	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.69502	1.67043	1.31072	1.31881	1.29245	0.965573	1.35028	1.27893	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.68088	1.86957	1.38587	1.31823	1.44703	0.951918	1.45118	1.30433	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.88295	2.10441	1.67603	1.40385	1.32214	0.992855	1.30867	1.35858	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.36234	1.55742	1.07986	1.08725	1.33654	0.856834	1.31238	1.10758	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.61058	1.7916	1.29589	1.2869	1.25668	0.799752	1.27172	1.20954	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.93823	2.11468	1.64001	1.47811	1.41107	0.889697	1.40948	1.42423	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.32026	1.74914	1.15414	1.18326	1.25333	0.863577	1.2964	1.15822	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.73717	2.1945	1.58595	1.57788	1.56416	0.918219	1.54895	1.50235	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.39504	1.51157	1.13989	1.12269	1.37667	1.03544	1.40463	1.14059	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.69097	1.73239	1.35056	1.31767	1.09679	0.939652	1.14876	1.27193	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.62558	1.66467	1.20047	1.16154	1.37298	0.90494	1.41278	1.19152	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.61426	1.99932	1.24924	1.0895	1.16919	0.824072	1.19023	1.07718	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.6901	1.75983	1.47876	1.13521	1.42138	1.02985	1.3973	1.04916	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.43406	1.54023	1.21325	1.02393	1.28915	1.00348	1.25021	0.971326	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.39857	1.73917	1.18266	0.977441	1.25133	0.786046	1.23068	0.931464	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.56232	1.80578	1.28071	1.067	1.22398	0.834402	1.20722	1.0198	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	2.22498	2.23726	2.08651	2.19615	1.80971	1.05205	1.77903	2.25157	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.57281	1.80577	1.15391	1.10941	1.16732	1.10875	1.14971	1.08692	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	2.01307	2.16241	1.913	2.01167	1.55932	1.0184	1.61414	2.01093	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.67958	1.82064	1.40386	1.28058	1.36764	1.12757	1.37761	1.21209	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.52283	1.58348	1.10584	1.05983	1.4148	0.963236	1.43633	1.05649	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.36632	1.4592	1.23164	1.24061	1.46875	0.955463	1.44463	1.23525	NA

Figures

pre

Positive Correlations (FDR = )

Negative Correlations (FDR = )

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13
Tract Name	Fornix_L	Cerebellum_R	Fornix_R	Corpus_Callosum_Forceps_Major	Thalamic_Radiation_Superior_L	Corpus_Callosum_Tapetum	Optic_Radiation_L	Thalamic_Radiation_Superior_R	Corticospinal_Tract_L	Cingulum_Frontal_Parietal_L	Optic_Radiation_R	NA
number of tracts	880	323	272	85	70	43	40	22	18	15	10	NA
mean length(mm)	59.1159	56.6502	57.9265	59.4588	55.5143	55.814	54.55	55.6364	56.2222	58.2667	52.2	NA
span(mm)	22.9562	25.8342	23.983	24.9055	17.9653	19.5002	26.1914	16.4482	27.4981	25.5424	21.0456	NA
curl	2.57516	2.19284	2.41532	2.38738	3.09008	2.86223	2.08274	3.38251	2.04458	2.28117	2.48032	NA
elongation	6.099	6.10906	8.39714	8.9873	10.5951	11.6451	12.8176	18.2524	18.7034	17.1213	22.2329	NA
diameter(mm)	9.69272	9.27314	6.89835	6.61588	5.23962	4.7929	4.25587	3.04817	3.00599	3.40316	2.34787	NA
volume(mm^3)	4362	3826	2165	2044	1197	1007	776	406	399	530	226	NA
trunk volume(mm^3)	2789	1980	1556	112	291	167	121	0	62	0	73	NA
branch volume(mm^3)	1573	1846	609	1932	906	840	655	406	337	530	153	NA
total surface area(mm^2)	12654	13208	7852	8809	5344	4179	4186	2446	1962	3522	1629	NA
total radius of end regions(mm)	16.3062	12.3786	12.4515	16.7307	15.3917	15.1211	13.2143	8.99344	7.76873	15.2854	7.81095	NA
total area of end regions(mm^2)	811	389	297	127	90	67	58	29	30	24	16	NA
irregularity	7.02956	8.00312	6.25472	7.12809	5.84806	4.97257	5.73939	4.59102	3.69533	5.65375	4.23084	NA
area of end region 1(mm^2)	374	203	124	60	47	36	29	14	16	12	8	NA
radius of end region 1(mm)	8.39552	5.63489	6.68495	8.96237	8.26499	8.73049	6.32685	4.55723	4.37691	7.27417	2.65763	NA
irregularity of end region 1	0.59207	0.491388	1.1322	4.20576	4.56601	6.65158	4.33637	4.6604	3.76154	13.8527	2.77363	NA
area of end region 2(mm^2)	437	186	173	67	43	31	29	15	14	12	8	NA
radius of end region 2(mm)	7.9107	6.74372	5.7665	7.76835	7.12675	6.3906	6.88748	4.43621	3.39181	8.01124	5.15332	NA
irregularity of end region 2	0.449882	0.768132	0.60385	2.82965	3.71078	4.13877	5.13893	4.12176	2.58158	16.8023	10.4288	NA
qa	0.156792	0.11764	0.149235	0.298184	0.169174	0.303226	0.244959	0.153841	0.294133	0.182193	0.167073	NA
nqa	0.240897	0.180744	0.229287	0.458133	0.259921	0.465879	0.376357	0.236363	0.451909	0.279924	0.256693	NA
gfa	0.087523	0.0388161	0.085935	0.121951	0.0822952	0.13406	0.098861	0.0798277	0.114833	0.0884387	0.0857949	NA
iso	0.382918	0.691591	0.365947	0.504218	0.433598	0.445191	0.551109	0.405388	0.544837	0.443201	0.41045	NA
dec_t	1.26302	0.758592	1.53229	0.833089	1.02547	0.506595	0.883773	1.04395	1.72815	1.00033	1.04634	NA
inc_t	0.0620926	0.167474	0.0777732	0.239787	0.0749169	0.249669	0.120734	0.0987231	0.0228521	0.11436	0.171514	NA
ICBM152_adult.T1W	165.398	170.713	164.503	187.786	190.832	199.034	194.455	193.029	213.758	203.322	158.796	NA
ICBM152_adult.WM	53.9414	35.6033	54.3804	158.174	124.708	193.114	159.046	121.491	239.445	171.666	91.5252	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.37702	1.1415	1.44248	1.67431	1.03654	1.58011	1.39631	1.04183	1.09576	1.0977	1.32021	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	2.15683	1.29272	2.11485	2.14086	1.94191	1.93855	1.89864	1.76691	1.12716	1.73494	1.95965	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.58376	0.914994	1.54363	1.56262	1.14592	1.58156	1.30923	1.03657	1.07534	1.09405	1.40329	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.39357	0.904493	1.36506	1.4033	1.03708	1.35782	1.18729	1.03484	1.07304	1.0687	1.14561	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.71213	0.914914	1.65419	1.68009	1.3478	1.49212	1.19304	1.13941	1.06492	1.22878	1.35038	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.58334	1.09618	1.61945	1.53728	1.22284	1.46322	1.2428	1.0517	1.08072	1.17188	1.24534	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	2.03089	1.22488	2.01651	1.83061	1.91533	1.74624	1.65936	1.69988	1.10521	1.53681	1.65265	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.46008	1.16795	1.4421	1.61818	1.09595	1.44252	1.22333	1.02604	1.06001	1.0923	1.28205	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.41664	0.981396	1.39763	1.39536	1.10342	1.35282	1.30066	1.03341	1.07674	1.12124	1.42745	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.42114	0.909526	1.65144	1.60598	1.15366	1.49083	1.27728	1.10911	1.12212	1.11264	1.30054	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.33915	0.89083	1.3699	1.45891	1.1671	1.50116	1.18952	0.98835	1.02309	1.05617	1.16668	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.53483	1.08787	1.77844	1.5674	1.37797	1.63604	1.29123	1.24507	1.14927	1.33695	1.62341	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.52694	1.01523	1.8404	1.53289	1.12048	1.58268	1.31966	1.15104	1.10407	1.10282	1.52662	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.79843	1.10667	1.98398	1.53608	1.46676	1.48667	1.26187	1.37741	1.12538	1.22048	1.65738	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.44437	0.944532	1.46809	1.6563	1.11893	1.41997	1.43952	1.06581	1.09688	1.13918	1.44458	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.58183	1.17978	1.79023	1.38739	1.31364	1.34681	1.16322	1.25604	1.09509	1.29628	1.57743	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.34103	1.20154	1.36227	1.53825	1.01894	1.47989	1.24768	1.01114	0.983256	1.03518	1.30955	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.60005	1.04151	1.74024	1.47959	1.38714	1.48302	1.25677	1.29	1.12132	1.17303	1.52718	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.58464	0.846609	1.63139	1.92941	1.40384	1.61005	1.68569	1.30956	1.04628	1.32012	1.43595	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	2.01523	0.9385	1.93344	1.85733	1.66163	1.72266	1.47624	1.35616	1.13691	1.45568	1.54448	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.57538	0.992694	1.55411	1.49806	1.22764	1.5598	1.21512	1.04785	1.12564	1.12311	1.31394	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.60265	1.00799	1.73097	1.56314	1.27425	1.55193	1.35785	1.19272	1.09122	1.20672	1.5707	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.81212	1.09821	2.0266	1.48242	1.55157	1.42512	1.29311	1.57385	1.12294	1.23833	1.38064	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.3364	1.10781	1.45216	1.44223	1.07556	1.36424	1.27579	1.01336	1.05367	1.11168	1.36288	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.54068	0.942766	1.6497	1.40431	1.22329	1.45088	1.18757	1.1048	1.10647	1.22364	1.36098	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.81985	1.08125	1.97435	1.47077	1.47837	1.4184	1.26146	1.41116	1.11816	1.33272	1.6868	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.30769	1.05174	1.66604	1.61449	1.12751	1.49244	1.27554	1.2554	1.06629	1.12608	1.29423	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.66813	0.914825	2.04549	1.75293	1.43805	1.59781	1.55062	1.47343	1.09099	1.30391	1.83675	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.37031	0.89951	1.39375	1.56633	1.11225	1.62023	1.28902	1.073	1.0976	1.04737	1.42848	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.63497	0.941146	1.66021	1.58731	1.23157	1.46848	1.21859	1.19202	1.12747	1.14569	1.43926	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.52272	1.0445	1.52648	1.55004	1.19805	1.51553	1.47172	1.10613	1.04768	1.14315	1.47779	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.5467	1.04677	1.83533	1.41105	1.16525	1.36589	1.1376	1.13877	1.05745	1.09815	1.50097	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.59545	0.933343	1.67937	1.5858	1.30868	1.50919	1.42878	1.19175	1.11162	1.12336	1.35133	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.40459	0.90798	1.41642	1.58576	1.1288	1.51988	1.35343	1.07657	1.08257	1.11136	1.45937	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.38188	0.866233	1.67229	1.39235	1.12417	1.40123	1.1615	1.21463	1.07743	1.04923	1.30455	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.47343	1.17195	1.65397	1.53662	1.17404	1.441	1.25543	1.22469	1.07913	1.08153	1.38803	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	2.16424	1.09287	2.18453	1.98902	2.05062	1.74219	1.77651	1.96383	1.08145	1.70256	1.7569	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.48528	0.932166	1.62624	1.42393	1.09138	1.3918	1.1539	1.03252	1.04417	1.08424	1.36825	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	1.90398	0.85627	2.03083	1.85173	1.80333	1.79611	1.65653	1.61525	1.10567	1.56743	1.717	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.62924	1.23304	1.70498	1.53185	1.28432	1.4677	1.51514	1.24983	1.18025	1.17948	1.49086	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.42724	0.928633	1.51109	1.55593	1.1007	1.43534	1.44078	1.02705	1.06146	1.10115	1.16466	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.34713	1.05714	1.34653	1.64429	1.18464	1.46535	1.50943	1.10853	1.06046	1.16113	1.46365	NA

Figures

peri

Positive Correlations (FDR = )

Negative Correlations (FDR = )

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17	V18	V19	V20	V21	V22	V23	V24	V25	V26	V27	V28	V29	V30	V31	V32	V33
Tract Name	Corpus_Callosum_Tapetum	Cerebellum_R	Corpus_Callosum_Forceps_Major	Cerebellum_L	Fornix_L	Corpus_Callosum_Body	Inferior_Longitudinal_Fasciculus_L	Arcuate_Fasciculus_R	Middle_Cerebellar_Peduncle	Corticostriatal_Tract_Posterior_R	Inferior_Fronto_Occipital_Fasciculus_R	Dentatorubrothalamic_Tract_R	Inferior_Longitudinal_Fasciculus_R	Corticospinal_Tract_R	Corticospinal_Tract_L	Fornix_R	Inferior_Fronto_Occipital_Fasciculus_L	Optic_Radiation_L	Corticopontine_Tract_Parietal_L	Dentatorubrothalamic_Tract_L	Arcuate_Fasciculus_L	Corticostriatal_Tract_Posterior_L	Cingulum_Parolfactory_R	Thalamic_Radiation_Posterior_L	Medial_Lemniscus_R	Superior_Longitudinal_Fasciculus2_L	Thalamic_Radiation_Posterior_R	Thalamic_Radiation_Anterior_R	Corpus_Callosum_Forceps_Minor	Anterior_Commissure	Corticopontine_Tract_Parietal_R	NA
number of tracts	187	106	85	63	56	50	37	36	35	34	31	26	25	25	20	20	19	19	18	18	16	16	15	14	14	13	13	12	12	11	10	NA
mean length(mm)	67.861	54.2264	62.2824	53.9365	60.4643	59.24	56.0541	63.6111	54.6857	57.7059	56.6452	60.9231	59.2	61.84	58.9	69.2	59.6842	59.8947	61.1111	56.3333	59.5	55.5	62.8	57.4286	63.8571	55.5385	58.3077	52.8333	59.5	58.5454	56	NA
span(mm)	24.4121	24.7535	24.067	24.9687	21.0073	23.1856	26.8727	23.0028	23.0734	25.6827	25.5956	27.5462	26.0643	29.2957	27.955	23.7237	27.9619	28.6987	28.5194	25.5413	25.1393	24.9305	28.2417	25.2103	28.1538	22.5045	24.8551	25.2105	23.4634	26	26.0864	NA
curl	2.77981	2.19065	2.58787	2.16016	2.87825	2.55504	2.08591	2.76536	2.37008	2.24688	2.21308	2.21167	2.2713	2.11089	2.10696	2.91692	2.13449	2.08702	2.14279	2.20558	2.36681	2.22619	2.22366	2.27798	2.26816	2.46788	2.34591	2.09569	2.53586	2.25175	2.14672	NA
elongation	6.67057	6.13344	7.71859	8.06639	10.4298	8.65445	10.0964	12.4558	9.93995	9.15161	9.64665	10.9953	10.7579	14.1094	13.9898	20.293	13.1476	13.2723	17.6867	12.6892	13.6803	13.4791	17.286	13.5769	17.876	16.1321	14.5246	15.4538	16.7738	17.7719	17.7456	NA
diameter(mm)	10.1732	8.8411	8.06914	6.68657	5.79725	6.84504	5.5519	5.10694	5.50161	6.30554	5.872	5.54083	5.50295	4.3829	4.21022	3.41005	4.53956	4.51277	3.45519	4.43946	4.34933	4.11747	3.633	4.22988	3.57224	3.44273	4.0144	3.41879	3.5472	3.29427	3.15572	NA
volume(mm^3)	5516	3329	3185	1894	1596	2180	1357	1303	1300	1802	1534	1469	1408	933	820	632	966	958	573	872	884	739	651	807	640	517	738	485	588	499	438	NA
trunk volume(mm^3)	347	246	91	170	0	0	0	71	0	0	0	125	0	100	186	112	0	79	178	78	0	0	0	110	128	91	0	0	0	127	0	NA
branch volume(mm^3)	5169	3083	3094	1724	1596	2180	1357	1232	1300	1802	1534	1344	1408	833	634	520	966	879	395	794	884	739	651	697	512	426	738	485	588	372	438	NA
total surface area(mm^2)	26939	17247	18824	9260	8896	15288	8384	6883	8988	12199	11567	11481	10809	5361	4991	4017	6992	5373	3709	6763	6287	6925	3569	6742	5301	4676	6260	3697	5313	3975	3598	NA
total radius of end regions(mm)	37.6263	17.2533	30.8251	9.56177	16.9901	32.9691	22.3446	23.6205	29.6233	22.4203	39.0095	43.9042	25.4112	15.1263	17.9092	13.3041	23.1645	12.5831	11.8707	18.9554	27.5207	25.0369	16.7816	26.7503	28.205	41.8618	26.2008	15.3166	23.7876	53.9598	12.1716	NA
total area of end regions(mm^2)	276	164	142	97	79	80	60	54	59	61	56	48	43	39	35	30	32	35	26	33	30	27	25	26	24	22	26	23	21	18	16	NA
irregularity	12.4209	11.4511	11.9226	8.17287	8.07837	12.0008	8.57537	6.74426	9.50932	10.6717	11.0693	10.8261	10.5613	6.29601	6.40646	5.41858	8.21445	6.32754	5.59132	8.60783	7.73311	9.64598	4.97933	8.83452	7.39704	7.78444	8.51291	6.51508	8.01286	6.56048	6.48075	NA
area of end region 1(mm^2)	135	77	71	46	47	40	29	29	32	30	29	24	22	20	17	16	18	18	13	17	15	13	13	12	12	12	13	11	11	10	7	NA
radius of end region 1(mm)	20.6051	7.32356	18.2434	3.73484	9.71401	16.4623	12.54	11.2833	20.3052	12.1933	20.7729	21.566	12.3497	6.57471	8.72392	9.96857	12.1761	6.62504	5.54667	12.5034	14.693	14.8119	8.65828	15.5392	12.9402	22.1432	15.1756	7.4519	11.4081	35.0328	8.38828	NA
irregularity of end region 1	9.88017	2.18828	14.7267	0.952656	6.30738	21.2849	17.0352	13.7919	40.4775	15.5694	46.7462	60.8806	21.7791	6.79006	14.0645	19.5117	25.8759	7.66045	7.43483	28.8908	45.2145	53.0186	18.1163	63.2161	43.8383	128.366	55.6539	15.8596	37.1695	385.568	31.5789	NA
area of end region 2(mm^2)	141	87	71	51	32	40	31	25	27	31	27	24	21	19	18	14	14	17	13	16	15	14	12	14	12	10	13	12	10	8	9	NA
radius of end region 2(mm)	17.0212	9.92971	12.5816	5.82693	7.27613	16.5068	9.80459	12.3372	9.31811	10.227	18.2365	22.3382	13.0615	8.55155	9.18528	3.33548	10.9884	5.95807	6.32401	6.45196	12.8277	10.225	8.12331	11.211	15.2648	19.7186	11.0252	7.86474	12.3794	18.9269	3.78333	NA
irregularity of end region 2	6.45523	3.56044	7.00431	2.09151	5.19757	21.4	9.74198	19.1268	10.1028	10.5996	38.6965	65.3182	25.5222	12.0917	14.7252	2.49654	27.095	6.56012	9.66478	8.17361	34.4633	23.4609	17.2756	28.2042	61.0027	122.153	29.3753	16.1934	48.1452	140.676	4.99639	NA
qa	0.296335	0.116333	0.332111	0.128864	0.159208	0.302124	0.198843	0.231803	0.209688	0.232012	0.221228	0.223915	0.206027	0.324875	0.325706	0.156229	0.260891	0.262275	0.332753	0.246155	0.230266	0.244525	0.199925	0.223027	0.247221	0.17261	0.226096	0.185142	0.220137	0.203702	0.253108	NA
nqa	0.455292	0.178736	0.510259	0.197989	0.244608	0.464187	0.305505	0.356145	0.322168	0.356466	0.339897	0.344025	0.316542	0.499142	0.500418	0.240032	0.400837	0.402963	0.511245	0.378195	0.353784	0.37569	0.307166	0.342661	0.379833	0.2652	0.347376	0.284455	0.338221	0.31297	0.388878	NA
gfa	0.133444	0.0385955	0.125443	0.0406948	0.0852446	0.129885	0.0968044	0.0981702	0.100797	0.0999906	0.0953607	0.102842	0.0950194	0.133906	0.132048	0.0908847	0.111152	0.102839	0.137535	0.104894	0.0936754	0.0996459	0.0975969	0.0943334	0.109391	0.0697864	0.0973669	0.0951471	0.101939	0.0959423	0.111485	NA
iso	0.432528	0.697311	0.555635	0.728421	0.392475	0.458745	0.437904	0.494151	0.428851	0.509561	0.514027	0.450712	0.484971	0.488886	0.495111	0.363554	0.501448	0.567808	0.469119	0.489199	0.517807	0.535767	0.455605	0.502289	0.46089	0.555392	0.500899	0.406552	0.455444	0.447966	0.467195	NA
dec_t	0.804814	1.21379	0.710693	0.921837	0.409006	0.728625	0.718269	0.787538	0.763529	0.809421	0.798364	0.595799	0.681646	0.755737	0.572204	0.219595	0.602151	0.395602	0.632019	0.613206	0.886251	0.783096	0.343802	0.576972	0.801194	0.884456	0.764758	0.5417	0.513455	0.680115	0.801881	NA
inc_t	0.171838	0.166446	0.203903	0.184256	0.219588	0.218673	0.243072	0.186984	0.253006	0.18051	0.209723	0.355148	0.215144	0.376846	0.353431	0.505657	0.2931	0.283665	0.230292	0.364379	0.149721	0.261111	0.366175	0.379447	0.318247	0.171168	0.29503	0.360186	0.278571	0.221153	0.232352	NA
ICBM152_adult.T1W	204.278	175.311	194.024	159.358	173.973	202.433	220.234	225.731	212.446	221.206	211.956	207.204	219.897	208.377	210.297	166.275	210.355	205.124	214.677	208.39	223.435	218.321	196.868	214.731	209.854	221.717	220.704	204.724	213.302	198.724	221.772	NA
ICBM152_adult.WM	199.831	48.7468	178.547	18.5828	69.1919	200.206	222.941	250.816	219.817	240.01	206.961	204.718	233.921	233.368	238.81	74.3437	209.995	185.251	242.969	217.343	251.156	233.189	155.136	219.447	218.278	246.713	232.804	176.344	217.958	150.055	250.635	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.44243	1.18435	1.53373	1.11596	1.1861	1.44093	1.2229	1.07948	1.34464	1.16156	1.17575	1.10393	1.15756	1.14659	1.11576	1.46619	1.39683	1.40581	1.19294	1.03095	1.11648	1.25494	1.13532	1.18082	1.13444	1.07862	1.13139	1.02888	1.4192	1.33552	1.11155	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.60475	0.939793	1.61043	0.97182	1.98279	1.55858	1.27918	1.11097	1.26358	1.10267	1.15796	1.13671	1.14597	1.2064	1.18407	1.93921	1.61608	1.79113	1.24727	1.12793	1.08009	1.30328	1.05725	1.23046	1.18573	1.07736	1.10503	1.12839	1.54723	1.57621	1.13615	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.43625	1.02869	1.40806	1.00834	1.32742	1.36194	1.17356	1.11591	1.32803	1.11747	1.16086	1.09643	1.12788	1.1356	1.091	1.56	1.28384	1.29586	1.16285	1.00936	1.06092	1.16457	1.07459	1.07055	1.12503	1.07062	1.08923	1.03956	1.35359	1.27955	1.08401	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.31156	0.914442	1.41628	0.851291	1.21955	1.40587	1.14369	1.11021	1.30749	1.12147	1.15437	1.14211	1.12368	1.18156	1.14273	1.39564	1.22725	1.20135	1.19506	1.03485	1.05687	1.16447	1.15145	1.08927	1.14468	1.02806	1.10091	1.05312	1.34825	1.2374	1.06748	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.39433	1.01296	1.55394	0.975557	1.49701	1.36025	1.10474	1.09713	1.23857	1.13982	1.15997	1.09414	1.10595	1.11232	1.1059	1.69107	1.27308	1.23931	1.19682	1.04887	1.05743	1.17918	1.10312	1.10912	1.11823	1.03237	1.10812	1.06415	1.26019	1.20128	1.07238	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.35839	0.926064	1.47981	1.0051	1.37062	1.39328	1.12393	1.06683	1.26353	1.12831	1.1649	1.0773	1.09501	1.1056	1.07278	1.6182	1.30683	1.33637	1.15082	1.02826	1.06671	1.172	1.0682	1.08852	1.11134	1.06129	1.095	1.05768	1.36664	1.18775	1.08169	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	1.49204	1.071	1.57852	1.11265	2.00716	1.43035	1.24273	1.1394	1.37177	1.07738	1.18435	1.121	1.1105	1.16464	1.14608	1.90119	1.43404	1.60713	1.2143	1.05538	1.04122	1.22598	1.08841	1.18889	1.16648	1.05109	1.12047	1.08488	1.34776	1.35977	1.10338	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.35187	0.955566	1.4671	1.07358	1.2443	1.32141	1.11096	1.12737	1.16378	1.10277	1.14055	1.10322	1.1142	1.12223	1.09293	1.46628	1.30388	1.29135	1.12513	1.01843	1.08517	1.18113	1.09234	1.13897	1.12948	1.04147	1.08992	1.11028	1.34263	1.20009	1.07184	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.27793	0.926276	1.31531	1.0807	1.24401	1.33531	1.08542	1.0595	1.24226	1.08941	1.13134	1.09537	1.09551	1.14304	1.12168	1.38712	1.25247	1.2903	1.19301	1.06223	1.01081	1.13794	1.14562	1.10178	1.11603	0.999287	1.08648	1.08281	1.36235	1.24383	1.06598	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.3699	0.869793	1.5567	0.89051	1.26776	1.34755	1.10573	1.13148	1.30952	1.13806	1.21543	1.1314	1.14045	1.18104	1.13605	1.65381	1.29986	1.3433	1.20306	1.08494	1.05745	1.18206	1.18339	1.11924	1.13993	1.03057	1.13283	1.06945	1.287	1.2636	1.0836	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.37735	0.878685	1.35634	0.928362	1.25776	1.34	1.1458	1.05264	1.17371	1.06283	1.11911	1.08026	1.08922	1.16776	1.07993	1.41652	1.2544	1.21283	1.16143	1.00304	1.00259	1.13424	1.105	1.06741	1.12784	0.962177	1.06921	0.966737	1.29085	1.17894	1.06624	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.48846	1.02463	1.45852	1.09142	1.36505	1.46989	1.17911	1.244	1.24257	1.18981	1.26066	1.16391	1.22014	1.20005	1.18121	1.77715	1.33393	1.29271	1.25165	1.1103	1.12142	1.23613	1.24458	1.20298	1.15972	1.0424	1.17907	1.12651	1.4501	1.31567	1.17638	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.4335	0.964646	1.58619	0.993182	1.28534	1.38909	1.19205	1.1318	1.33383	1.15934	1.29083	1.12065	1.17092	1.1549	1.1235	1.80648	1.32233	1.28959	1.15423	1.0404	1.07821	1.1733	1.06889	1.14072	1.10952	1.03424	1.18356	1.10532	1.38718	1.35667	1.12965	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.45458	0.933213	1.43828	1.15497	1.6161	1.41006	1.21223	1.10616	1.20035	1.14642	1.18711	1.14982	1.18186	1.19915	1.13084	1.90056	1.2871	1.25989	1.21104	1.04989	1.06973	1.19937	1.14446	1.14615	1.21976	1.03807	1.13415	1.07851	1.33554	1.32995	1.11173	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.32371	0.945042	1.37343	0.928816	1.21856	1.27456	1.15643	1.13396	1.2554	1.11191	1.15433	1.08107	1.14888	1.12156	1.08768	1.42291	1.38328	1.45235	1.15831	1.03213	1.03179	1.19544	1.13057	1.12044	1.11294	0.976082	1.11406	1.05625	1.28856	1.27373	1.09447	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.43534	1.12889	1.37321	1.17108	1.37381	1.46302	1.18819	1.08701	1.24185	1.13421	1.16577	1.11168	1.12627	1.16472	1.15112	1.77578	1.24129	1.16332	1.19347	1.05981	1.00726	1.14073	1.06239	1.14324	1.15078	0.971297	1.13435	1.09829	1.43203	1.23924	1.12712	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.35197	1.02351	1.39368	0.980913	1.18751	1.30053	1.15728	1.06644	1.19475	1.07194	1.11459	1.05839	1.09547	1.09994	1.07158	1.40435	1.32455	1.3076	1.15302	0.991107	1.05683	1.1991	1.10225	1.1237	1.0517	0.982537	1.06332	1.0288	1.28725	1.16515	1.04485	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.43217	1.07599	1.37835	1.179	1.48883	1.40573	1.19894	1.14895	1.31636	1.15256	1.17148	1.11478	1.16238	1.14712	1.14185	1.73422	1.28286	1.25924	1.1937	1.07562	1.03814	1.18004	1.10687	1.14471	1.12933	1.04156	1.11573	1.07108	1.35179	1.33052	1.13122	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.50129	0.905433	1.60759	0.900121	1.4141	1.49206	1.23391	1.11522	1.16857	1.15698	1.22049	1.1077	1.15247	1.18193	1.1248	1.67937	1.49945	1.64912	1.2184	1.04405	1.10194	1.28816	1.10042	1.15271	1.13195	1.0583	1.12254	1.14753	1.44598	1.46272	1.1277	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	1.47863	0.939709	1.55494	0.933496	1.83219	1.44253	1.14912	1.14283	1.39955	1.1411	1.19575	1.13771	1.18607	1.14625	1.18969	1.87368	1.46713	1.5319	1.25166	1.08269	1.04921	1.22275	1.08021	1.17188	1.14884	1.00599	1.16008	1.08988	1.42402	1.3606	1.14658	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.4334	0.92288	1.35882	0.905941	1.32265	1.4064	1.1504	1.09769	1.12105	1.15011	1.17971	1.11211	1.1475	1.2052	1.13884	1.5997	1.32816	1.25583	1.23356	1.05696	1.03611	1.19625	1.04026	1.13061	1.17578	1.05172	1.12609	1.07095	1.41377	1.22732	1.13868	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.47598	0.930469	1.56114	0.995589	1.39599	1.43935	1.23866	1.14177	1.17611	1.1538	1.28265	1.11695	1.1517	1.10577	1.09936	1.69648	1.36343	1.3391	1.16586	0.99591	1.07409	1.24003	1.16833	1.16125	1.09335	1.06874	1.1739	1.11842	1.44005	1.39479	1.11285	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.366	1.13797	1.41478	1.0976	1.72044	1.35967	1.15672	1.11768	1.30371	1.13377	1.18145	1.08781	1.16077	1.13236	1.11914	1.93625	1.29437	1.29924	1.20502	1.05218	1.02443	1.23709	1.12865	1.18263	1.15845	1.00693	1.1759	1.02027	1.30946	1.317	1.13503	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.29825	0.953625	1.38711	0.984467	1.17983	1.29629	1.15263	1.07722	1.18019	1.08031	1.14226	1.06351	1.14379	1.09615	1.0829	1.45532	1.28708	1.2656	1.13166	1.01649	1.02704	1.14275	1.17425	1.09237	1.06572	1.00586	1.08067	1.0926	1.28227	1.27219	1.0597	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.3983	0.913465	1.32939	0.956128	1.31424	1.41078	1.12618	1.09187	1.26479	1.10944	1.11399	1.10938	1.1324	1.15619	1.15312	1.63803	1.2173	1.1902	1.19592	1.08885	1.04288	1.13574	1.19821	1.12055	1.13452	1.02057	1.09041	1.03923	1.29603	1.19817	1.10816	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.48584	1.05596	1.36123	1.08109	1.59825	1.439	1.21866	1.16518	1.35035	1.17197	1.21656	1.13743	1.17941	1.14834	1.09911	1.92928	1.3209	1.25191	1.19854	1.06547	1.08305	1.23589	1.20014	1.19108	1.1619	1.02736	1.14125	1.08826	1.35779	1.348	1.15766	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.44424	0.939123	1.55753	0.937783	1.19838	1.42674	1.16163	1.11678	1.29684	1.12518	1.12907	1.12309	1.10515	1.16829	1.15749	1.71593	1.31705	1.31767	1.17922	1.02807	1.0842	1.1888	1.14633	1.13052	1.14755	0.985516	1.14595	1.02996	1.35321	1.26884	1.12003	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.49471	1.02166	1.60616	1.02685	1.55763	1.44207	1.15819	1.13216	1.34371	1.18882	1.25714	1.12965	1.17829	1.16496	1.1212	1.89337	1.39707	1.51209	1.21127	1.06272	1.08284	1.24802	1.05523	1.21529	1.16009	1.06895	1.17999	1.09698	1.41446	1.41643	1.20131	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.45895	0.967617	1.41527	1.01721	1.23623	1.39735	1.20175	1.07878	1.26029	1.05631	1.12399	1.07111	1.09648	1.15128	1.10386	1.36301	1.32131	1.2753	1.12694	1.02083	1.05391	1.16641	1.07384	1.11515	1.10774	1.01817	1.06902	1.06353	1.40778	1.34032	1.04708	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.34325	0.892391	1.40455	0.952657	1.43004	1.33232	1.03695	1.07085	1.12019	1.07772	1.1116	1.07773	1.0857	1.12651	1.1019	1.67353	1.2857	1.30681	1.14294	1.05212	1.00241	1.11444	1.01303	1.04394	1.09426	0.95772	1.05953	1.01683	1.31237	1.11953	1.04401	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.44176	1.00484	1.36685	1.02055	1.28322	1.42355	1.15576	1.09282	1.25501	1.13549	1.14517	1.09985	1.16763	1.12705	1.11922	1.52919	1.39684	1.48566	1.18757	1.02677	1.08365	1.20969	1.0943	1.14983	1.11171	1.02903	1.11755	1.10541	1.3745	1.28041	1.11213	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.27926	0.92148	1.2242	0.941931	1.31662	1.24823	1.08037	1.01598	1.21708	1.04805	1.05857	1.07706	1.04737	1.07342	1.07135	1.73494	1.15903	1.16231	1.14055	0.972769	0.96672	1.1221	1.152	1.1076	1.06159	1.01044	1.03063	1.04244	1.21575	1.21341	1.00865	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.38648	0.965871	1.49666	1.00266	1.4466	1.34357	1.20279	1.13961	1.26673	1.11256	1.19003	1.08001	1.14152	1.14654	1.11504	1.69961	1.37951	1.45352	1.21325	1.04065	1.06285	1.22101	1.13813	1.12752	1.11932	1.00964	1.10495	1.0496	1.26571	1.32638	1.10407	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.3796	0.956024	1.46134	0.895183	1.24141	1.35555	1.14492	1.08742	1.33193	1.06479	1.16538	1.09761	1.10983	1.12096	1.1232	1.40006	1.32837	1.38302	1.17414	1.04349	1.01378	1.1953	1.14441	1.11823	1.09876	1.01679	1.07274	1.09149	1.29904	1.25351	1.03043	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.35162	0.88771	1.35495	0.930653	1.27429	1.3562	1.23141	1.07726	1.18891	1.06843	1.13643	1.10837	1.13593	1.13716	1.14518	1.71363	1.22356	1.17035	1.20295	1.04233	1.01967	1.16316	1.14183	1.11228	1.1113	0.996568	1.08713	1.06588	1.30712	1.22795	1.04416	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.36002	0.963632	1.4683	1.06891	1.32814	1.29977	1.20603	1.09036	1.20022	1.09969	1.15563	1.08963	1.12824	1.13154	1.10179	1.64097	1.31358	1.31004	1.15579	1.00648	1.05432	1.21906	1.13894	1.16429	1.11139	1.00214	1.10661	1.05021	1.28183	1.19123	1.06228	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	1.52562	1.11814	1.54456	1.11055	2.08946	1.446	1.22396	1.0874	1.07567	1.10206	1.15231	1.09159	1.1142	1.11732	1.09448	1.99729	1.50761	1.66483	1.20536	1.03606	1.0206	1.28323	1.09577	1.31989	1.11668	0.959112	1.15517	1.101	1.43348	1.55873	1.06417	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.33159	0.964949	1.43366	0.968576	1.24812	1.29774	1.14472	1.10042	1.23528	1.04065	1.1458	1.09617	1.10511	1.13764	1.10395	1.61771	1.23261	1.16701	1.15823	1.01125	1.03692	1.12644	1.12148	1.10087	1.07117	0.976575	1.05463	1.05851	1.36036	1.19533	1.00842	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	1.61119	0.997475	1.73047	0.944934	1.82494	1.52571	1.25295	1.18791	1.31223	1.20113	1.28528	1.19196	1.20537	1.22104	1.20042	1.98792	1.55653	1.65628	1.30189	1.10259	1.08775	1.29519	1.12795	1.18675	1.1979	1.03758	1.22263	1.16775	1.46815	1.42572	1.19358	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.38392	1.05017	1.40247	1.00164	1.42978	1.35571	1.23402	1.10669	1.32217	1.08377	1.18012	1.10613	1.14806	1.1611	1.14148	1.68784	1.41335	1.50644	1.21228	1.03742	1.08764	1.22627	1.09213	1.11992	1.12776	1.04548	1.08581	1.08846	1.31933	1.29179	1.07387	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.39007	0.921827	1.47119	1.02183	1.23911	1.37589	1.1919	1.05067	1.13161	1.09374	1.19853	1.09986	1.08958	1.13387	1.08027	1.54122	1.39731	1.43361	1.15516	1.01912	1.02241	1.19826	1.06991	1.09226	1.09861	1.00781	1.08689	1.07646	1.35745	1.28829	1.05378	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.41841	0.983913	1.56694	1.02649	1.24805	1.37199	1.22066	1.09984	1.19186	1.14572	1.18498	1.14735	1.09498	1.19217	1.15023	1.3295	1.44084	1.50069	1.19479	1.06696	1.09108	1.24508	1.20005	1.11918	1.16976	0.984022	1.17376	1.16846	1.35542	1.30076	1.14173	NA

Figures

post

Positive Correlations (FDR = )

Negative Correlations (FDR = )

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14
Tract Name	Cerebellum_R	Cerebellum_L	Fornix_L	Corpus_Callosum_Tapetum	Corpus_Callosum_Forceps_Major	Corticostriatal_Tract_Posterior_R	Thalamic_Radiation_Superior_L	Fornix_R	Corpus_Callosum_Body	Inferior_Longitudinal_Fasciculus_R	Cingulum_Parolfactory_R	Middle_Cerebellar_Peduncle	NA
number of tracts	98	41	37	33	27	18	16	16	15	14	11	10	NA
mean length(mm)	55.8163	53.6585	57.4054	56.1818	60	54.5556	60.625	58.625	58.2667	53.8571	54.5455	53.8	NA
span(mm)	25.8391	24.0734	22.6851	22.7555	23.7668	25.7988	18.2805	24.6133	19.6649	24.7899	25.3908	19.9317	NA
curl	2.16015	2.22895	2.53053	2.46893	2.52453	2.11465	3.31637	2.38184	2.96299	2.17254	2.14824	2.69922	NA
elongation	6.68186	9.03333	12.0103	9.99556	11.5395	12.3436	19.8981	18.9002	13.4722	13.6036	18.8424	16.4131	NA
diameter(mm)	8.35342	5.94006	4.77966	5.62068	5.19953	4.41976	3.04677	3.10181	4.32496	3.95904	2.89483	3.27787	NA
volume(mm^3)	3059	1487	1030	1394	1274	837	442	443	856	663	359	454	NA
trunk volume(mm^3)	370	73	0	0	0	0	0	0	104	64	0	0	NA
branch volume(mm^3)	2689	1414	1030	1394	1274	837	442	443	752	599	359	454	NA
total surface area(mm^2)	16740	10844	6581	9438	9489	6793	2914	2829	7243	5035	2381	3951	NA
total radius of end regions(mm)	13.3287	15.5333	14.6988	31.1558	26.7597	26.5599	13.6556	11.2261	39.2338	29.5107	8.31607	24.8112	NA
total area of end regions(mm^2)	136	55	51	53	46	30	19	26	28	26	15	16	NA
irregularity	11.4283	10.8295	7.6347	9.51362	9.68178	8.96756	5.02166	4.95205	9.14885	7.51651	4.79985	7.13154	NA
area of end region 1(mm^2)	64	27	24	26	23	14	12	10	14	13	8	8	NA
radius of end region 1(mm)	4.9644	6.80287	7.40334	14.483	16.8972	16.7997	9.35098	5.40002	23.6172	14.5655	3.50596	15.2182	NA
irregularity of end region 1	1.20977	5.38482	7.17454	25.3451	38.9988	63.3324	22.8919	9.16095	125.164	51.2694	4.82696	90.9467	NA
area of end region 2(mm^2)	72	28	27	27	23	16	7	16	14	13	7	8	NA
radius of end region 2(mm)	8.36426	8.73039	7.29542	16.6728	9.86254	9.76018	4.30458	5.82612	15.6166	14.9452	4.81011	9.59295	NA
irregularity of end region 2	3.05262	8.55183	6.19279	32.3446	13.2862	18.7045	8.31597	6.66483	54.7264	53.9773	10.3839	36.138	NA
qa	0.113174	0.120835	0.159667	0.318856	0.300627	0.238796	0.178114	0.15409	0.296767	0.208152	0.1926	0.194998	NA
nqa	0.173883	0.185653	0.245314	0.489894	0.461887	0.366889	0.273656	0.236746	0.455956	0.319808	0.295913	0.299598	NA
gfa	0.0376294	0.0407121	0.0901919	0.139571	0.116978	0.102399	0.086559	0.0900583	0.127785	0.0873681	0.089707	0.095305	NA
iso	0.689552	0.704765	0.380438	0.44225	0.541735	0.503395	0.425501	0.357178	0.46085	0.512676	0.488861	0.428733	NA
dec_t	0.406912	0.466407	1.10486	0.820284	0.603644	0.449951	0.918052	0.515722	0.973608	0.369261	0.992257	0.755513	NA
inc_t	0.365001	0.482648	0.27851	0.38128	0.348741	0.630374	0.166284	0.477125	0.256754	0.836844	0.272859	0.50363	NA
ICBM152_adult.T1W	175.044	169.621	170.208	209.644	195.9	220.918	184.413	157.984	207.014	228.829	181.023	207.479	NA
ICBM152_adult.WM	47.7014	34.6553	64.3642	213.99	181.192	238.401	114.675	50.555	212.531	245.12	97.3368	207.031	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.21766	1.02641	1.40593	1.35837	1.45683	1.15948	1.10783	1.58928	1.326	1.08982	1.11262	1.30463	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.03041	1.01215	2.17826	1.52647	1.69664	1.10509	1.91302	2.17783	1.44132	1.07543	1.11757	1.24058	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.02337	0.933305	1.63191	1.35837	1.42632	1.09685	1.26617	1.69167	1.28809	1.10725	1.05394	1.32473	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	0.979925	0.836262	1.42284	1.27706	1.3151	1.10715	1.15231	1.46936	1.30089	1.09897	1.10602	1.29745	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	0.970989	0.918416	1.77239	1.32678	1.52274	1.14564	1.45164	1.79575	1.32479	1.06039	1.16096	1.23419	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.00485	0.941159	1.63238	1.30344	1.39549	1.09144	1.34348	1.7866	1.29438	1.08041	1.10572	1.28959	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	1.09789	1.08231	2.06672	1.42602	1.57495	1.11149	1.94602	2.09523	1.40872	1.08493	1.15532	1.31884	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.00373	0.958328	1.48481	1.28233	1.37915	1.11322	1.18341	1.57538	1.27022	1.10872	1.08931	1.13892	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.01688	1.0381	1.43706	1.23715	1.33536	1.08305	1.16637	1.53177	1.2255	1.08035	1.10515	1.22363	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	0.933603	0.887459	1.44383	1.3348	1.47355	1.12483	1.22695	1.83892	1.30421	1.11309	1.16187	1.28041	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	0.902834	0.93247	1.38389	1.30191	1.32435	1.06034	1.2788	1.49569	1.29075	1.06498	1.05777	1.2482	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.03727	1.02226	1.59545	1.44786	1.49034	1.18759	1.42021	1.92547	1.39642	1.20389	1.2635	1.35195	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	0.964616	0.96036	1.57573	1.39755	1.5239	1.13718	1.17253	2.00204	1.33292	1.21626	1.08079	1.29048	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.07739	1.12291	1.89342	1.40229	1.48332	1.1331	1.63613	2.14915	1.39819	1.09281	1.21307	1.28964	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.01386	0.94436	1.48807	1.28405	1.45132	1.0945	1.1906	1.5933	1.24716	1.12093	1.1821	1.23779	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.32548	1.0891	1.65551	1.38249	1.34291	1.15871	1.3349	1.9317	1.3729	1.14227	1.02582	1.22815	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.13903	0.97032	1.36711	1.26983	1.41579	1.04962	1.05943	1.48175	1.24024	1.08843	1.14981	1.24324	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.16579	1.16132	1.66364	1.36493	1.33845	1.1784	1.52177	1.88642	1.32846	1.09752	1.11154	1.29815	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	0.865776	0.869475	1.63977	1.41098	1.62201	1.14509	1.54476	1.78842	1.36169	1.05469	1.02719	1.24412	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	0.962107	0.931354	2.04415	1.40589	1.59363	1.16422	1.7357	2.05796	1.39759	1.09202	1.17523	1.34307	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.0227	0.909397	1.63401	1.37038	1.34744	1.13372	1.31712	1.72779	1.33032	1.11107	1.00724	1.13388	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.01296	0.916874	1.65306	1.38866	1.45672	1.16449	1.3619	1.90112	1.3581	1.07804	1.13434	1.27296	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.13156	1.074	1.88973	1.32258	1.38791	1.13334	1.66515	2.14947	1.33533	1.08734	1.11711	1.25611	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.02243	0.960027	1.35705	1.22616	1.33821	1.08514	1.08601	1.59859	1.22856	1.07671	1.12516	1.17357	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	0.907896	0.947057	1.57987	1.3794	1.33275	1.1005	1.28097	1.78461	1.36712	1.07241	1.16256	1.24093	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.06383	1.0058	1.86502	1.42562	1.37061	1.16772	1.61011	2.11908	1.3919	1.09329	1.21118	1.30927	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.02692	0.913313	1.36814	1.41523	1.43153	1.14858	1.16735	1.86163	1.34048	1.07943	1.15955	1.33654	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.00402	0.981082	1.67956	1.41054	1.59686	1.17728	1.50255	2.12754	1.37251	1.04918	1.06677	1.31158	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	0.959817	1.00183	1.4017	1.37104	1.46425	1.05092	1.14222	1.51044	1.31673	1.09734	1.06182	1.29142	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	0.966128	0.875397	1.67142	1.28672	1.42704	1.06779	1.34678	1.78812	1.2944	1.03275	1.123	1.22631	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	0.994489	0.99054	1.55741	1.41136	1.40364	1.12164	1.20849	1.69002	1.33257	1.09353	1.1574	1.29399	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	0.971401	0.898289	1.58875	1.23746	1.297	1.06048	1.2032	1.99739	1.23857	1.02667	1.14651	1.22234	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	0.995627	1.0216	1.6462	1.3305	1.42282	1.11691	1.45959	1.84973	1.33871	1.10602	1.10372	1.22375	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	0.980662	0.882924	1.45451	1.31694	1.48433	1.03927	1.23696	1.552	1.27266	1.06265	1.07326	1.23865	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	0.83991	0.883353	1.40632	1.27807	1.29813	1.04708	1.2069	1.84344	1.26252	1.05123	1.10043	1.16497	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.02388	0.991653	1.54182	1.32455	1.37258	1.09821	1.22728	1.82003	1.27324	1.14448	1.13778	1.21425	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	1.14487	1.11146	2.1624	1.42705	1.64408	1.09806	1.983	2.18901	1.39471	1.06082	1.0809	1.11741	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.00376	0.972487	1.54691	1.28517	1.34864	1.03346	1.18731	1.8203	1.22009	1.13221	1.13222	1.25269	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	0.916655	0.904298	1.97237	1.50048	1.64698	1.18352	1.85205	2.13887	1.42715	1.13223	1.10428	1.29883	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.14588	1.0487	1.68247	1.32728	1.39955	1.09233	1.39676	1.8518	1.29425	1.18848	1.09116	1.35253	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	0.997525	0.960113	1.42683	1.29269	1.38908	1.0712	1.13751	1.63334	1.30911	1.01407	1.0561	1.20636	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.09767	0.971008	1.39593	1.3457	1.44311	1.1599	1.2306	1.46948	1.28781	1.0794	1.13037	1.23391	NA

Figures

Peri and Post

Positive Correlations (FDR = )

Negative Correlations (FDR = )

V1	V2	V3	V4	V5	V6	V7	V8	V9	V10	V11	V12	V13	V14	V15	V16	V17	V18	V19	V20
Tract Name	Corpus_Callosum_Tapetum	Fornix_L	Cerebellum_R	Corpus_Callosum_Forceps_Major	Corpus_Callosum_Body	Thalamic_Radiation_Superior_L	Cingulum_Frontal_Parietal_L	Inferior_Fronto_Occipital_Fasciculus_L	Cerebellum_L	Optic_Radiation_L	Thalamic_Radiation_Anterior_L	Inferior_Longitudinal_Fasciculus_L	Cingulum_Parolfactory_R	Anterior_Commissure	Thalamic_Radiation_Superior_R	Arcuate_Fasciculus_L	Cingulum_Frontal_Parahippocampal_L	Thalamic_Radiation_Posterior_L	NA
number of tracts	1226	501	364	360	300	241	128	87	64	60	33	32	30	25	19	13	11	10	NA
mean length(mm)	59.8887	55.0228	54.9099	56.2382	55.0351	57.0684	59.4798	54.2143	52.257	53.641	53.0334	56.7611	54.6772	58.5027	56.6408	67.5389	62.0182	58.6093	NA
span(mm)	23.0349	21.2746	25.8355	22.3947	21.2982	18.0732	25.7073	25.5539	24.3949	25.7384	24.2716	27.144	25.8375	28.0447	17.0118	25.4128	25.7148	13.2004	NA
curl	2.59991	2.58631	2.12537	2.51122	2.58402	3.15763	2.31374	2.12157	2.14213	2.08408	2.185	2.09111	2.1162	2.08605	3.3295	2.65767	2.41177	4.43997	NA
elongation	4.51986	5.73418	6.40257	6.11981	7.29372	6.99422	12.5639	8.78939	8.89985	9.79302	15.9932	12.4207	18.0972	13.4834	16.7284	28.7862	18.6263	18.3811	NA
diameter(mm)	13.2501	9.59557	8.57623	9.18954	7.54555	8.15937	4.73417	6.16816	5.87166	5.47747	3.31599	4.56988	3.02131	4.33885	3.38591	2.34622	3.3296	3.18856	NA
volume(mm^3)	8258	3979	3172	3730	2461	2984	1047	1620	1415	1264	458	931	392	865	510	292	540	468	NA
trunk volume(mm^3)	0	2726	2721	421	1788	1079	451	423	581	716	249	343	232	365	194	241	0	134	NA
branch volume(mm^3)	8258	1253	451	3309	673	1905	596	1197	834	548	209	588	160	500	316	51	540	334	NA
total surface area(mm^2)	19137	11252	7360	12085	7326	9572	3840	5176	5810	4121	2319	4341	1538	3539	2304	1587	3985	2749	NA
total radius of end regions(mm)	32.8165	12.8825	8.57697	29.3568	12.3802	16.7987	8.69367	18.6564	8.8892	7.21893	6.30822	27.2121	6.59675	6.53955	11.4442	2.77503	16.2521	19.2262	NA
total area of end regions(mm^2)	1436	545	395	485	349	344	149	126	99	93	48	54	43	46	34	22	20	20	NA
irregularity	7.67643	6.7837	4.97486	7.4434	5.61547	6.54335	4.34078	4.92691	6.02727	4.46453	4.19748	5.32702	2.9635	4.43792	3.82409	3.18789	6.14281	4.68235	NA
area of end region 1(mm^2)	718	279	183	246	169	191	75	65	48	44	24	27	20	22	17	12	10	10	NA
radius of end region 1(mm)	16.6702	7.44576	4.00511	18.675	5.95792	8.73076	3.67558	11.3385	4.23791	2.59297	2.56697	14.3088	3.25196	2.33661	8.16864	1.54238	7.70502	14.2364	NA
irregularity of end region 1	1.21592	0.624257	0.275377	4.45383	0.659861	1.25378	0.565901	6.21364	1.17547	0.480055	0.862545	23.8226	1.66115	0.779649	12.3311	0.622804	18.6508	63.6723	NA
area of end region 2(mm^2)	718	266	212	239	180	153	74	61	51	49	24	27	23	24	17	10	10	10	NA
radius of end region 2(mm)	16.1463	5.43678	4.57187	10.6819	6.42225	8.06798	5.01809	7.31791	4.65129	4.62596	3.74125	12.9034	3.34479	4.20294	3.27556	1.23265	8.54707	4.98975	NA
irregularity of end region 2	1.1407	0.349101	0.309743	1.49985	0.719867	1.33656	1.06904	2.758	1.33268	1.37201	1.8322	19.3727	1.52813	2.3123	1.98276	0.477345	22.9501	7.82182	NA
qa	0.318543	0.146993	0.113318	0.360407	0.361364	0.16051	0.124042	0.242017	0.133094	0.240337	0.113155	0.224644	0.186514	0.238323	0.173338	0.127433	0.130165	0.203824	NA
nqa	0.489414	0.225842	0.174103	0.553733	0.555204	0.24661	0.19058	0.371837	0.204487	0.369257	0.173853	0.345146	0.286563	0.366162	0.266318	0.19579	0.199987	0.313157	NA
gfa	0.141133	0.0825864	0.0373387	0.140489	0.153211	0.0804185	0.0602649	0.110526	0.0416275	0.104687	0.0565134	0.10488	0.0856414	0.105417	0.0877095	0.0608377	0.0639821	0.0982858	NA
iso	0.432339	0.387294	0.705463	0.521769	0.445853	0.422609	0.454353	0.465633	0.735139	0.492563	0.459666	0.453794	0.507964	0.488596	0.403641	0.476158	0.446017	0.424525	NA
dec_t	1.01336	0.645181	0.836062	0.721683	1.11303	0.568983	0.550621	0.593385	0.67994	0.542209	0.528851	0.772552	0.234498	0.565625	0.228554	0.781521	0.477706	0.586243	NA
inc_t	0.075908	0.145227	0.0854902	0.0959671	0.0594916	0.0877072	0.0981668	0.136507	0.158391	0.142242	0.115801	0.0874213	0.391055	0.132117	0.435069	0.0815939	0.11439	0.0682009	NA
ICBM152_adult.T1W	197.743	174.006	184.942	194.824	205.728	183.8	195.45	191.596	153.276	181.779	197.211	191.742	156.835	181.338	167.89	201.359	190.415	191.351	NA
ICBM152_adult.WM	184.574	71.7215	74.0861	173.363	207.547	111.305	115.561	161.114	12.7161	139.79	124.421	170.131	21.7359	141.936	80.2216	146.26	105.365	138.005	NA
sub-307_space-T1w_desc-preproc_dwi mean_ad	1.56789	1.19689	1.32647	1.81263	1.44011	1.05856	1.02291	1.45974	1.09963	1.56667	0.962105	1.43825	1.09778	1.54484	1.23863	0.947486	1.02782	1.20459	NA
sub-310_space-T1w_desc-preproc_dwi mean_ad	1.73827	2.08959	0.926641	1.95965	1.5967	1.98211	2.12032	1.90857	0.957154	2.11636	2.11543	1.85626	1.13596	2.13764	2.01366	1.97939	2.06647	2.04971	NA
sub-311_space-T1w_desc-preproc_dwi mean_ad	1.53823	1.39896	1.11976	1.57346	1.37412	1.22789	1.06159	1.43638	0.998611	1.45831	0.997754	1.41543	1.02064	1.43095	1.19825	0.986904	1.09577	1.25043	NA
sub-312_space-T1w_desc-preproc_dwi mean_ad	1.38202	1.20815	0.97148	1.45568	1.37602	1.05273	1.01129	1.22629	0.844237	1.24892	0.960589	1.20742	1.08599	1.2335	1.08227	0.943479	1.01424	1.13783	NA
sub-313_space-T1w_desc-preproc_dwi mean_ad	1.50249	1.65496	1.0919	1.79992	1.39215	1.46166	1.28891	1.28228	1.06613	1.34749	1.14207	1.24674	1.22536	1.3431	1.34004	1.13037	1.3323	1.51719	NA
sub-315_space-T1w_desc-preproc_dwi mean_ad	1.44688	1.47945	0.921852	1.74203	1.41017	1.28517	1.16848	1.30444	1.05398	1.37142	1.0592	1.22896	1.15145	1.32898	1.28952	1.03111	1.18173	1.35104	NA
sub-319_space-T1w_desc-preproc_dwi mean_ad	1.60575	2.1657	0.993818	1.87126	1.46671	1.98875	1.82921	1.73629	1.26738	1.89468	1.71809	1.67846	1.21595	1.87639	1.82157	1.59589	1.88261	2.04114	NA
sub-321_space-T1w_desc-preproc_dwi mean_ad	1.42401	1.28757	0.884831	1.71954	1.26542	1.14713	1.05277	1.29412	1.0411	1.34027	1.0024	1.27651	1.08396	1.32639	1.13447	0.968238	1.08752	1.17585	NA
sub-322_space-T1w_desc-preproc_dwi mean_ad	1.32995	1.25308	0.962955	1.41717	1.29993	1.12431	1.09466	1.34511	1.06927	1.41147	1.01066	1.32271	1.06153	1.38708	1.17255	0.988028	1.11453	1.19789	NA
sub-323_space-T1w_desc-preproc_dwi mean_ad	1.4735	1.32118	0.89426	1.76541	1.33378	1.21751	1.05939	1.31556	0.906851	1.42028	1.00943	1.24861	1.12727	1.38562	1.31486	0.992284	1.08097	1.28579	NA
sub-324_space-T1w_desc-preproc_dwi mean_ad	1.46493	1.26217	0.866191	1.53489	1.35902	1.22896	1.0095	1.30094	0.91261	1.31534	0.9702	1.27428	1.01087	1.30577	1.08989	0.947425	1.05365	1.26391	NA
sub-325_space-T1w_desc-preproc_dwi mean_ad	1.58267	1.44784	0.966302	1.63648	1.51056	1.45113	1.4238	1.34106	1.14034	1.36862	1.26867	1.32936	1.26705	1.36052	1.54428	1.23968	1.41529	1.50309	NA
sub-326_space-T1w_desc-preproc_dwi mean_ad	1.52377	1.36376	0.938709	1.75803	1.35937	1.16174	1.06542	1.38716	0.945955	1.4252	1.0117	1.40395	1.12474	1.42904	1.39751	0.979085	1.09845	1.25437	NA
sub-327_space-T1w_desc-preproc_dwi mean_ad	1.57482	1.7898	0.999274	1.56164	1.49995	1.60116	1.26202	1.35816	1.12208	1.38924	1.13399	1.35008	1.21315	1.36347	1.66606	1.11996	1.32511	1.69581	NA
sub-328_space-T1w_desc-preproc_dwi mean_ad	1.39147	1.28266	1.08039	1.59276	1.22493	1.17237	1.07364	1.44525	0.950363	1.53731	1.0149	1.40445	1.17294	1.51727	1.17476	0.982473	1.08487	1.20648	NA
sub-330_space-T1w_desc-preproc_dwi mean_ad	1.55285	1.43485	1.24983	1.42999	1.45945	1.35649	1.4019	1.26469	1.10795	1.23199	1.29336	1.25305	0.998068	1.24042	1.56483	1.22656	1.38978	1.38604	NA
sub-333_space-T1w_desc-preproc_dwi mean_ad	1.44454	1.19295	1.06089	1.54917	1.28531	1.02876	0.953206	1.3578	0.978739	1.39763	0.944662	1.30515	1.14897	1.37705	1.16231	0.938505	0.982283	1.14606	NA
sub-334_space-T1w_desc-preproc_dwi mean_ad	1.53923	1.56997	1.14769	1.45186	1.43924	1.49484	1.21329	1.34947	1.1406	1.36762	1.08153	1.33404	1.09985	1.35962	1.59711	1.03881	1.28423	1.56687	NA
sub-337_space-T1w_desc-preproc_dwi mean_ad	1.63841	1.48337	0.816787	1.89519	1.55166	1.49155	1.47539	1.76194	0.898279	1.93452	1.3001	1.66384	0.984365	1.92625	1.72258	1.26177	1.47632	1.43636	NA
sub-339_space-T1w_desc-preproc_dwi mean_ad	1.58981	1.96565	0.989448	1.82418	1.45048	1.75061	1.65092	1.57026	0.951059	1.72771	1.51517	1.47328	1.2444	1.68914	1.44567	1.39725	1.68502	1.80783	NA
sub-340_space-T1w_desc-preproc_dwi mean_ad	1.52229	1.43969	0.986906	1.46863	1.39254	1.28223	1.22483	1.32975	0.920062	1.33942	1.10293	1.27172	0.982385	1.31943	1.23029	1.06419	1.23063	1.33662	NA
sub-345_space-T1w_desc-preproc_dwi mean_ad	1.59672	1.46633	0.989823	1.67226	1.46399	1.34755	1.24209	1.47975	1.00646	1.51057	1.14151	1.46439	1.13125	1.49572	1.4078	1.08235	1.28619	1.36252	NA
sub-346_space-T1w_desc-preproc_dwi mean_ad	1.44816	1.81448	1.056	1.53157	1.37261	1.65951	1.32538	1.30934	1.05435	1.38927	1.1935	1.28268	1.09864	1.3552	1.70765	1.13487	1.39231	1.7479	NA
sub-348_space-T1w_desc-preproc_dwi mean_ad	1.35764	1.19604	0.933978	1.48428	1.28074	1.07622	1.07367	1.35678	1.13271	1.37841	1.08161	1.32902	1.07904	1.35967	1.16496	1.04256	1.08185	1.14016	NA
sub-350_space-T1w_desc-preproc_dwi mean_ad	1.51679	1.37247	0.894826	1.42587	1.43334	1.26213	1.20275	1.23941	0.9942	1.27313	1.06863	1.18317	1.12117	1.23273	1.3826	1.04289	1.17542	1.32989	NA
sub-351_space-T1w_desc-preproc_dwi mean_ad	1.62748	1.72305	1.01298	1.44548	1.47596	1.58791	1.39839	1.34304	1.01934	1.37388	1.28139	1.33397	1.19832	1.35931	1.74163	1.2252	1.4398	1.53763	NA
sub-353_space-T1w_desc-preproc_dwi mean_ad	1.55486	1.19892	0.959822	1.82442	1.45061	1.15413	1.13954	1.34124	0.96307	1.42454	1.07153	1.32262	1.13817	1.41516	1.58849	1.05123	1.14884	1.21667	NA
sub-354_space-T1w_desc-preproc_dwi mean_ad	1.57316	1.64046	1.02778	1.78625	1.48559	1.54577	1.46077	1.61769	1.02277	1.75985	1.29021	1.56778	1.08252	1.72063	1.77243	1.26055	1.4899	1.55799	NA
sub-355_space-T1w_desc-preproc_dwi mean_ad	1.57641	1.23127	1.01864	1.63535	1.3937	1.13599	1.0676	1.42584	1.0347	1.44041	1.00346	1.40814	1.06542	1.43597	1.28493	0.986932	1.09365	1.23905	NA
sub-356_space-T1w_desc-preproc_dwi mean_ad	1.43076	1.48506	0.981764	1.60832	1.28882	1.31457	1.23695	1.28636	0.984542	1.39485	1.11407	1.18512	1.2158	1.33606	1.41587	1.06247	1.24844	1.31816	NA
sub-357_space-T1w_desc-preproc_dwi mean_ad	1.52901	1.37607	0.951675	1.51257	1.46231	1.20876	1.12393	1.55051	1.05672	1.66865	1.09186	1.45104	1.1578	1.63417	1.26249	1.0612	1.16711	1.30383	NA
sub-358_space-T1w_desc-preproc_dwi mean_ad	1.35311	1.39777	0.933466	1.29175	1.24959	1.2292	1.06545	1.19575	0.910058	1.2062	1.04399	1.15718	1.1311	1.19402	1.37094	0.994882	1.11973	1.29419	NA
sub-359_space-T1w_desc-preproc_dwi mean_ad	1.49748	1.53672	1.03472	1.67024	1.36407	1.42523	1.10731	1.46507	0.98017	1.58149	1.03547	1.43031	1.07433	1.54886	1.37468	1.0288	1.17145	1.47713	NA
sub-360_space-T1w_desc-preproc_dwi mean_ad	1.50138	1.28117	1.08664	1.65976	1.35984	1.19102	0.99944	1.42967	0.925273	1.49529	0.946557	1.36966	1.0313	1.46507	1.32302	0.931928	1.0348	1.22337	NA
sub-362_space-T1w_desc-preproc_dwi mean_ad	1.42674	1.27209	0.806613	1.39706	1.36002	1.16704	0.965964	1.23717	0.976385	1.23235	0.935421	1.24265	1.03626	1.2207	1.47819	0.935056	1.0152	1.2631	NA
sub-363_space-T1w_desc-preproc_dwi mean_ad	1.46342	1.39394	0.911383	1.67188	1.31869	1.24591	1.05116	1.31323	1.05129	1.34548	1.01277	1.26275	1.10583	1.33145	1.46933	0.995762	1.11273	1.27785	NA
sub-364_space-T1w_desc-preproc_dwi mean_ad	1.63882	2.17029	1.11457	1.81191	1.47647	2.06871	2.12686	1.7924	1.05759	1.96274	2.11508	1.72712	1.01281	1.92879	1.98656	1.94905	2.09418	2.15937	NA
sub-366_space-T1w_desc-preproc_dwi mean_ad	1.40771	1.33228	1.12699	1.53805	1.25902	1.14222	1.05531	1.22449	1.00297	1.19624	0.981936	1.20549	1.16056	1.19237	1.21716	0.960273	1.073	1.19338	NA
sub-368_space-T1w_desc-preproc_dwi mean_ad	1.77712	1.987	1.01518	1.96405	1.57897	1.88734	1.91195	1.74253	0.92506	1.93154	1.85072	1.64739	1.10358	1.87566	1.92912	1.71282	1.90777	1.87031	NA
sub-369_space-T1w_desc-preproc_dwi mean_ad	1.47017	1.48923	1.13878	1.54008	1.32973	1.36428	1.20863	1.5185	1.01975	1.59653	1.06921	1.41836	1.08066	1.56351	1.45653	1.04684	1.24286	1.37952	NA
sub-373_space-T1w_desc-preproc_dwi mean_ad	1.51542	1.29734	1.05688	1.6369	1.38337	1.10207	1.03925	1.52221	1.03879	1.60164	1.01395	1.4733	1.03061	1.58978	1.23908	1.00277	1.05799	1.19416	NA
sub-376_space-T1w_desc-preproc_dwi mean_ad	1.51307	1.25665	1.10052	1.77865	1.41183	1.22782	1.17314	1.59019	1.04563	1.71003	1.08079	1.52985	1.06249	1.67583	1.28368	1.04724	1.20013	1.30478	NA

Figures

RD

All subjects

Positive Correlations (FDR = )

Not significant

Negative Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_R	423	55.8203	6.19769	1684
Fornix_L	183	55.7705	5.20569	1187
Corpus_Callosum_Body	18	50.3333	3.91205	605
Cingulum_Frontal_Parietal_L	10	56.8	1.92319	165

Figures

Men

Positive Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	3786	59.0951	11.996	6679
Fornix_R	656	55.1037	9.35803	3790
Thalamic_Radiation_Superior_L	433	56.8037	8.59137	3293
Corpus_Callosum_Forceps_Major	254	59.1732	6.93631	2236
Corpus_Callosum_Tapetum	47	55.4894	5.03992	1107
Cerebellum_L	45	51.9556	3.77335	581
Thalamic_Radiation_Posterior_L	44	54.8182	4.9759	1066
Cingulum_Frontal_Parietal_L	33	61.3333	4.06247	795
Thalamic_Radiation_Superior_R	20	55	3.2024	443
Cingulum_Frontal_Parahippocampal_L	15	63.8667	3.22901	523
Thalamic_Radiation_Anterior_L	14	52.1429	2.9276	351

Negative Correlations (FDR = )

Figures

Women

Positive Correlations (FDR = )

Negative Correlations (FDR = )

.
Cerebellum_R
19
54.1065
3.50482
522

Figures

pre

Positive Correlations (FDR = )

Negative Correlations (FDR = )

.
Cerebellum_R
19
54.1065
3.50482
522

Figures

peri

Positive Correlations (FDR = )

Negative Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Corpus_Callosum_Body	114	59.7895	9.42234	4169
Corpus_Callosum_Forceps_Major	109	59.8899	9.22049	3999
Corpus_Callosum_Tapetum	89	61.3483	8.1825	3226
Cerebellum_R	71	54	8.00834	2720
Fornix_L	65	62	6.00683	1757
Corpus_Callosum_Forceps_Minor	56	57.9643	7.16174	2335
Cerebellum_L	48	53.2917	6.83263	1954
Inferior_Longitudinal_Fasciculus_R	20	60.3	4.78422	1084
Corticostriatal_Tract_Posterior_R	20	53.3	4.69307	922
Thalamic_Radiation_Posterior_R	18	54.7778	4.45013	852
Fornix_R	17	56.4706	3.07363	419
Arcuate_Fasciculus_R	16	55.5	4.18654	764
Dentatorubrothalamic_Tract_L	14	56.8571	3.73514	623
Middle_Cerebellar_Peduncle	14	61.1429	3.71288	662
Reticular_Tract_R	12	56.1667	3.02626	404
Dentatorubrothalamic_Tract_R	11	53.0909	3.88392	629
Cingulum_Frontal_Parietal_L	10	58.8	3.29042	500
Cingulum_Parolfactory_R	10	65.4	2.16158	240
Corticospinal_Tract_L	10	57.6	2.66377	321

Figures

post

Positive Correlations (FDR = )

Negative Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Cerebellum_R	140	55.5429	10.6674	4964
Fornix_L	129	59.0078	6.64599	2047
Corpus_Callosum_Tapetum	59	61.9322	7.20204	2523
Cerebellum_L	56	56.5357	6.49822	1875
Corpus_Callosum_Body	54	56.8519	7.89051	2780
Middle_Cerebellar_Peduncle	51	58.5098	7.42288	2532
Corpus_Callosum_Forceps_Major	36	63.2222	6.52797	2116
Fornix_R	34	56.4118	3.75587	625
Corpus_Callosum_Forceps_Minor	34	55.2353	5.99281	1558
Inferior_Longitudinal_Fasciculus_R	29	58.1379	5.8768	1577
Dentatorubrothalamic_Tract_R	23	59.3913	5.3317	1326
Arcuate_Fasciculus_L	18	53.8889	4.81683	982
Corticospinal_Tract_R	18	62.5556	4.12007	834
Inferior_Fronto_Occipital_Fasciculus_R	17	57.5294	4.4556	897
Corticostriatal_Tract_Posterior_R	17	61.6471	4.67899	1060
Arcuate_Fasciculus_R	15	57.4667	4.34732	853
Superior_Longitudinal_Fasciculus2_R	14	62.8571	4.14942	850
Thalamic_Radiation_Superior_L	13	60.3077	3.61797	620
Dentatorubrothalamic_Tract_L	12	54.8333	3.80954	625
Corticospinal_Tract_L	11	55.6364	3.21621	452
Medial_Lemniscus_R	11	64	3.5766	643
Cingulum_Frontal_Parietal_R	10	61.8	3.6679	653
Frontal_Aslant_Tract_R	10	54.6	3.1221	418
Corticopontine_Tract_Parietal_R	10	59.6	3.34897	525

Figures

Peri and Post

Positive Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Middle_Cerebellar_Peduncle	318	55.1761	7.75175	2604
Cerebellum_R	295	54.0339	11.2583	5379
Inferior_Longitudinal_Fasciculus_L	234	55.6838	7.83689	2686
Cerebellum_L	217	52.9217	9.3838	3660
Corpus_Callosum_Tapetum	210	56.6476	11.019	5402
Fornix_L	209	57.3397	6.57691	1948
Corpus_Callosum_Forceps_Major	198	58.0303	10.1235	4671
Fornix_R	115	55.2348	6.54971	1861
Corpus_Callosum_Body	96	57.6667	7.64342	2646
Arcuate_Fasciculus_L	72	56.25	5.92324	1550
Thalamic_Radiation_Posterior_L	56	53.4286	5.10595	1094
Thalamic_Radiation_Superior_L	47	54.383	5.78213	1428
Optic_Radiation_L	36	55.2222	4.28674	797
Cingulum_Frontal_Parahippocampal_L	26	69.6154	4.26379	994
Vermis	26	53.7692	3.16489	423
Cingulum_Parahippocampal_Parietal_R	21	56	3.56825	560
Cingulum_Frontal_Parietal_L	19	66.2105	3.40526	603
Inferior_Fronto_Occipital_Fasciculus_L	19	52	3.93068	631
Thalamic_Radiation_Posterior_R	18	53.7778	3.76903	600
Inferior_Cerebellar_Peduncle_R	18	57	3.80163	647
Thalamic_Radiation_Anterior_L	17	54.5882	2.98886	383
Corticostriatal_Tract_Anterior_R	13	53.3846	2.51403	265
Cingulum_Frontal_Parietal_R	11	58.1818	3.18998	465

Negative Correlations (FDR = )

Tract Name	number of tracts	mean length(mm)	diameter(mm)	volume(mm^3)
Fornix_L	877	56.2144	9.69517	4150
Corpus_Callosum_Tapetum	632	57.5063	9.48113	4060
Cerebellum_R	244	55.0574	8.05978	2809
Thalamic_Radiation_Superior_L	146	58.0137	6.24502	1777
Corpus_Callosum_Forceps_Major	112	54.1786	6.20627	1639
Fornix_R	66	52.1818	5.50055	1240
Cingulum_Frontal_Parietal_L	60	59.3333	5.18332	1252
Corpus_Callosum_Forceps_Minor	54	55.037	5.05602	1105
Corpus_Callosum_Body	54	55.3333	5.53415	1331
Cerebellum_L	37	52.3243	5.92771	1444
Thalamic_Radiation_Anterior_L	19	54	3.06722	399
Cingulum_Frontal_Parietal_R	15	55.8667	3.27634	471
Uncinate_Fasciculus_R	15	53.2	3.12102	407
Dentatorubrothalamic_Tract_R	15	56.5333	2.81562	352
Cingulum_Frontal_Parahippocampal_L	14	61.8571	3.6634	652
Cingulum_Parolfactory_R	10	54.2	2.40882	247

Figures