Overview

This is the analysis of white matter dsi studio connectometry for Maze and Loop

Methods

Participants

  • Total number of scans = 120 (males and females)

  • Total scans used in analysis= 118

  • Excluded subs 329 and 372 from analyses due to bad behavior data and Subject 347 failed quality control check in DSI

  • Several subjects removed because they did not have rad3 score

Loop: Position Error, Degree Error, Angular Error

  • Rad 3
    • All subjects: 38
    • Men: 14
    • Women: 24
    • Stage:
      • Pre: 10
      • Peri: 7
      • Post: 7
  • Average
    • All subjects: 42
    • Men: 17
    • Women: 25
    • Stage:
      • Pre: 11
      • Peri: 7
      • Post: 7

Scan parameters

  • Locations from UCSB and UCI

QSIprep

  • Version used: 0.16.0RC3

  • The following parameters were used

    • dwi_denoise_window 5
    • hmc_model 3dSHORE
    • hmc-transform Rigid
    • shoreline_iters 2
      DSI Studio
  • Version and tags used via singularity container: chen-2022-07-31

  • Parameters

    • T-threshold = 2.5
    • Length = 25
    • Permutation = 4,000
    • pruning 4
    • non normalized QA
Connectronomy analysis methods write up
A diffusion spectrum imaging scheme was used, and a total of 128 diffusion sampling were acquired.The maximum b-value was 4990 s/mm². The in-plane resolution was 1.8 mm. The slice thickness was 1.8 mm. The accuracy of b-table orientation was examined by comparing fiber orientations with those of a population-averaged template (Yeh et al. Neuroimage, 2018). The b-table was flipped by. The diffusion data were reconstructed in the MNI space using q-space diffeomorphic reconstruction (Yeh et al., Neuroimage, 58(1):91-9, 2011) to obtain the spin distribution function (Yeh et al., IEEE TMI, ;29(9):1626-35, 2010). A diffusion sampling length ratio of 1.25 was used. The output resolution in diffeomorphic reconstruction was 1.8 mm isotropic. The tensor metrics were calculated using DWI with b-value lower than 1750 s/mm². The quantitative anisotropy was extracted as the local connectome fingerprint (LCF, Yeh et al. PLoS Comput Biol 12(11): e1005203) and used in the connectometry analysis.


Diffusion MRI connectometry (Yeh et al. NeuroImage 125 (2016): 162-171) was used to derive the correlational tractography that has QA, MD, AD, and RD correlated with Maze Accuracy and Loop variables. A nonparametric Spearman partial correlation was used to derive the correlation, and the effect of sex, age_scan_years, and repo_status was removed using a multiple regression model. The total number of subjects varied on analysis (See Analyses and Final sample sizes above). A T-score threshold of 2.5 was assigned and tracked using a deterministic fiber tracking algorithm (Yeh et al. PLoS ONE 8(11): e80713, 2013) to obtain correlational tractography. A seeding region was placed at whole brain (39,49,29) .

The tracks were filtered by topology-informed pruning (Yeh et al. Neurotherapeutics, 16(1), 52-58, 2019) with 4 iteration(s). A length threshold of 25 voxel distance was used to select tracks. To estimate the false discovery rate, a total of 4000 randomized permutations were applied to the group label to obtain the null distribution of the track length.




Behavior

Angular error is the degree difference btween the start location and the end location. Participants were tested on three different sizes of circles: Radius 1m, 2m, and 3m. For white matter analysis we used the data from radius 3 and an average of performance on all three circle sizes. The average position error on the 1m circle is 47.6146335. The average position error on the 2m circle is 56.1275526. The average position error on the 3m circle is 68.3846003. The average position error across all sizes is 56.4495802.

There are were significant differences in performance between men and women on the rad3 loop (t test, p= 0.50858) and on the average of all circles ( p = 0.4163938). The mean distance for degrees traveled in men on the rad3 circle was 64.924295, and in women it was 70.4031117. Men undershot the target location while women overshot the location The mean for the average of all circles in men is 51.2907976 and women is 59.9575524.

The average for degrees traveled on rad3
pre = 71.073026

peri = 73.2993367

post = 71.0431529

The average for degrees traveled on average of all circles
pre = 62.239975

peri = 63.5120417

post = 55.5092757





Results


Loop angular error Rad3

QA

All subjects

Positive Correlations (FDR = 0.000675)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 877 55.9796 12.0679 6403
Cerebellum_L 64 53.1643 4.58556 878
Fornix_R 12 52.1689 2.5954 276
Cingulum_Frontal_Parietal_L 10 52.4089 1.953 157

Negative Correlations (FDR = 0.004296)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corticospinal_Tract_R 304 55.1267 8.55124 3166
Arcuate_Fasciculus_R 182 52.5773 5.35013 1182
Medial_Lemniscus_R 52 56.3921 4.97225 1095
Corpus_Callosum_Tapetum 23 52.788 3.23916 435


Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3







Men

Positive Correlations (FDR = 0.012481)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 994 58.7371 13.4206 8309
Cerebellum_L 631 56.935 10.6459 5068
Cerebellum_R 249 53.6912 9.48158 3791
Corticospinal_Tract_R 238 59.1276 7.75247 2791
Corpus_Callosum_Tapetum 170 59.6702 9.6741 4386
Arcuate_Fasciculus_L 159 55.8202 7.70542 2603
Inferior_Fronto_Occipital_Fasciculus_R 156 57.063 6.75498 2045
Corpus_Callosum_Body 154 59.7992 9.43738 4183
Superior_Longitudinal_Fasciculus2_R 129 56.3811 7.73299 2648
Arcuate_Fasciculus_R 116 57.8156 7.73957 2720
Superior_Longitudinal_Fasciculus3_R 96 60.4046 6.44723 1972
Medial_Lemniscus_R 90 56.6319 6.76737 2037
Corticostriatal_Tract_Superior_R 69 55.5161 5.76474 1449
Vermis 63 53.215 5.77937 1396
Corpus_Callosum_Forceps_Major 59 62.0339 6.02566 1769
Cingulum_Frontal_Parietal_L 53 61.7079 3.18616 492
Inferior_Longitudinal_Fasciculus_R 51 54.9511 5.04392 1098
Corticopontine_Tract_Parietal_R 50 60.2026 5.63052 1499
Thalamic_Radiation_Posterior_L 47 54.3075 5.31519 1205
Middle_Cerebellar_Peduncle 47 67.1561 4.36728 1006
Corticopontine_Tract_Parietal_L 39 57.7474 5.65617 1451
Corticostriatal_Tract_Posterior_L 38 65.009 5.66576 1639
Thalamic_Radiation_Anterior_R 34 57.6071 3.81935 660
Corticostriatal_Tract_Posterior_R 33 55.2883 5.01246 1091
Inferior_Fronto_Occipital_Fasciculus_L 18 55.2274 3.66302 582
Parietal_Aslant_Tract_L 18 61.678 2.37395 273
Cingulum_Frontal_Parahippocampal_L 15 57.4842 2.63722 314
Cingulum_Parolfactory_L 13 65.2353 2.72336 380
Extreme_Capsule_R 13 53.9993 3.22829 442
Frontal_Aslant_Tract_R 13 54.6191 3.28883 464
Dentatorubrothalamic_Tract_R 13 52.9296 2.95094 362



Negative Correlations (FDR = 0.024096)
.
Cerebellum_L
116
55.5436
7.63954
2546



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in men

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in men

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in men







Women

Positive Correlations (FDR = 0.015385)
.
Cerebellum_L
35
54.407
3.71266
589



Negative Correlations (FDR = 0.001027)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corticospinal_Tract_R 239 55.4744 7.1526 2229
Arcuate_Fasciculus_R 114 54.341 4.77717 974
Medial_Lemniscus_R 95 57.0645 4.7495 1011
Corpus_Callosum_Tapetum 60 54.4736 4.43891 843
Inferior_Longitudinal_Fasciculus_R 25 57.4453 3.14057 445
Corticostriatal_Tract_Superior_R 20 53.9077 3.42961 498
Cingulum_Frontal_Parietal_L 16 53.6303 2.50826 265
Dentatorubrothalamic_Tract_R 15 51.746 3.22617 423



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in women


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in women

Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in women







pre

Positive Correlations (FDR = 0.036981)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Major 532 62.1823 10.7882 5684
Corpus_Callosum_Tapetum 438 55.1425 11.7919 6022
Corpus_Callosum_Body 346 59.1443 9.77555 4439
Cerebellum_L 155 55.1539 7.57713 2487
Corpus_Callosum_Forceps_Minor 134 57.2479 7.07245 2249
Fornix_L 60 61.0718 4.38192 921
Fornix_R 57 56.4362 3.77901 633
Arcuate_Fasciculus_L 50 54.402 3.53524 534
Inferior_Longitudinal_Fasciculus_L 27 56.5924 5.23694 1219
Thalamic_Radiation_Posterior_L 24 53.8504 4.31094 786
Corticostriatal_Tract_Posterior_L 20 54.8058 3.57456 550
Cingulum_Frontal_Parietal_R 14 62.1548 2.87679 404



Negative Correlations (FDR = 0.009185)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Inferior_Fronto_Occipital_Fasciculus_R 510 63.0641 9.04814 4055
Corticospinal_Tract_L 271 57.1097 11.0875 5514
Inferior_Fronto_Occipital_Fasciculus_L 262 56.5833 7.10437 2243
Corticospinal_Tract_R 251 58.6942 8.60702 3415
Cerebellum_L 222 56.1792 7.86447 2729
Cingulum_Frontal_Parietal_L 204 55.5582 6.13807 1644
Middle_Cerebellar_Peduncle 174 55.7707 8.49636 3162
Corpus_Callosum_Tapetum 162 60.7 7.25022 2506
Inferior_Longitudinal_Fasciculus_R 148 58.2545 5.78277 1530
Arcuate_Fasciculus_L 117 58.4216 7.03056 2268
Medial_Lemniscus_L 114 57.2181 7.15872 2303
Corticostriatal_Tract_Superior_L 107 56.5335 8.3584 3102
Medial_Lemniscus_R 80 55.1851 6.23326 1684
Dentatorubrothalamic_Tract_L 70 55.1835 7.00213 2125
Cingulum_Parolfactory_R 69 59.4306 3.99242 744
Arcuate_Fasciculus_R 64 60.978 6.21183 1848
Superior_Longitudinal_Fasciculus2_R 64 56.7607 5.33534 1269
Cingulum_Frontal_Parietal_R 62 55.4943 5.40012 1271
Corpus_Callosum_Body 53 54.5364 5.5849 1336
Uncinate_Fasciculus_R 51 56.2061 4.06932 731
Vermis 50 53.4535 4.85852 991
Corticopontine_Tract_Parietal_L 49 65.4395 4.3711 982
Superior_Longitudinal_Fasciculus2_L 40 55.5082 5.31812 1233
Cingulum_Frontal_Parahippocampal_L 36 53.5589 3.89753 639
Dentatorubrothalamic_Tract_R 36 55.5621 5.1089 1139
Extreme_Capsule_L 18 59.1259 3.47884 562
Cingulum_Frontal_Parahippocampal_R 15 56.408 2.66649 315
Corticopontine_Tract_Parietal_R 13 60.3215 3.60294 615
Extreme_Capsule_R 12 53.1778 2.41705 244
Corpus_Callosum_Forceps_Major 12 62.6695 2.78586 382
Superior_Longitudinal_Fasciculus3_L 10 53.0228 2.9928 373
Corticostriatal_Tract_Posterior_R 10 54.2202 3.2795 458



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in pre menopausal women


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in pre menopausal women


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in pre menopausal women







peri

Positive Correlations (FDR = 0.317868)
No Significant Findings



Negative Correlations (FDR = 0.029057)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Body 330 65.9288 14.8677 11446
Corticospinal_Tract_R 247 65.1614 10.797 5966
Inferior_Fronto_Occipital_Fasciculus_R 237 62.9996 11.1414 6142
Corpus_Callosum_Tapetum 230 64.0876 12.4875 7849
Cerebellum_L 226 55.824 13.6766 8201
Superior_Longitudinal_Fasciculus2_R 222 63.6687 11.0012 6052
Arcuate_Fasciculus_R 217 68.5276 10.5223 5959
Middle_Cerebellar_Peduncle 194 61.8863 11.7635 6726
Corpus_Callosum_Forceps_Major 165 60.5409 10.4133 5156
Cingulum_Frontal_Parietal_R 164 67.6788 8.10524 3492
Corticostriatal_Tract_Posterior_R 164 65.9497 10.4386 5644
Arcuate_Fasciculus_L 156 58.5221 10.6119 5176
Dentatorubrothalamic_Tract_R 132 60.3919 10.8337 5567
Medial_Lemniscus_R 117 64.7779 8.32734 3528
Cerebellum_R 112 54.0119 11.2533 5372
Inferior_Fronto_Occipital_Fasciculus_L 107 63.858 8.71128 3806
Inferior_Longitudinal_Fasciculus_L 103 61.2768 8.57526 3539
Inferior_Longitudinal_Fasciculus_R 99 60.4508 9.74312 4507
Corticostriatal_Tract_Posterior_L 83 60.9943 8.90054 3795
Corticospinal_Tract_L 82 62.5653 7.91577 3079
Frontal_Aslant_Tract_L 80 61.3321 8.23794 3269
Corticopontine_Tract_Parietal_R 80 62.2362 7.68523 2887
Superior_Longitudinal_Fasciculus2_L 78 60.0313 8.49067 3399
Dentatorubrothalamic_Tract_L 77 58.3208 8.58 3372
Corticostriatal_Tract_Superior_L 65 57.147 8.1058 2949
Thalamic_Radiation_Posterior_R 63 60.3866 7.08243 2379
Thalamic_Radiation_Anterior_R 62 66.3354 6.61821 2282
Cingulum_Frontal_Parietal_L 58 60.6987 6.36768 1933
Corticostriatal_Tract_Superior_R 58 62.875 7.70151 2929
Corpus_Callosum_Forceps_Minor 58 61.6993 7.08284 2431
Medial_Lemniscus_L 56 58.516 6.31193 1831
Vermis 56 56.2245 6.62987 1941
Thalamic_Radiation_Superior_R 50 64.7278 7.14598 2596
Superior_Longitudinal_Fasciculus1_R 49 65.5205 5.81321 1739
Anterior_Commissure 45 65.2566 6.16506 1948
Extreme_Capsule_R 42 62.6303 5.72815 1614
Cingulum_Parahippocampal_Parietal_R 40 56.8632 5.66649 1434
Corticopontine_Tract_Parietal_L 38 65.4282 6.00172 1851
Reticular_Tract_R 36 62.3961 6.4393 2032
Superior_Longitudinal_Fasciculus3_R 31 60.652 5.2899 1333
Parietal_Aslant_Tract_L 29 58.9126 4.83128 1080
Corticopontine_Tract_Frontal_R 29 58.1488 5.48102 1372
Cingulum_Parolfactory_R 25 66.169 4.14528 893
Middle_Longitudinal_Fasciculus_R 23 58.529 5.07082 1182
Thalamic_Radiation_Posterior_L 22 58.7316 5.03631 1170
Extreme_Capsule_L 20 63.405 4.68279 1092
Optic_Radiation_L 17 55.7674 3.51125 540
Superior_Longitudinal_Fasciculus3_L 16 59.756 4.44671 928
Corticopontine_Tract_Occipital_R 16 64.6266 3.27979 546
Reticular_Tract_L 16 64.0179 4.49301 1015
Frontal_Aslant_Tract_R 13 53.6847 4.01 678
Parietal_Aslant_Tract_R 13 57.8639 3.78188 650
Corticopontine_Tract_Frontal_L 12 67.5064 3.65684 709
Cingulum_Parolfactory_L 11 60.1934 2.12261 213
Thalamic_Radiation_Superior_L 11 62.7421 3.76899 700
Cingulum_Frontal_Parahippocampal_R 10 68.0192 3.07153 504
Middle_Longitudinal_Fasciculus_L 10 56.2141 3.62761 581



Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in peri menopausal women

Glass Brain displaying tracts that had QA negatively correlated with loop angular error rad3 in peri menopausal women







post

Positive Correlations (FDR = 1.000000)
No Significant Findings



Negative Correlations (FDR = 0.302332)
No Significant Findings











Peri + Post

Positive Correlations (FDR = 0.082506)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 681 58.7354 11.7131 6329
Corpus_Callosum_Body 366 56.2798 12.6399 7062
Middle_Cerebellar_Peduncle 306 59.0543 10.7821 5392
Corpus_Callosum_Forceps_Major 173 61.4656 7.70776 2868
Corpus_Callosum_Tapetum 157 54.9597 8.07268 2813
Inferior_Fronto_Occipital_Fasciculus_R 83 55.7638 6.1006 1630
Uncinate_Fasciculus_R 55 57.9419 4.89184 1089
Cingulum_Frontal_Parietal_L 47 56.1396 3.59549 570
Cerebellum_L 42 53.2038 3.941 649
Cingulum_Frontal_Parietal_R 40 58.206 4.37497 875
Cingulum_Parolfactory_L 32 53.8777 2.88008 351
Cingulum_Parolfactory_R 29 57.8008 2.84716 368
Inferior_Longitudinal_Fasciculus_R 14 52.2868 2.95257 358
Thalamic_Radiation_Anterior_R 13 55.0804 3.24311 455



Negative Correlations (FDR = 0.081279)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 920 66.7952 14.7981 11488
Corpus_Callosum_Body 803 65.7615 16.6946 14395
Corpus_Callosum_Forceps_Major 538 70.7981 12.2352 8324
Cerebellum_R 495 56.2048 13.646 8220
Corpus_Callosum_Tapetum 404 63.2638 12.3203 7542
Corticospinal_Tract_R 392 62.4423 8.81294 3809
Arcuate_Fasciculus_L 222 56.3231 9.9914 4416
Inferior_Fronto_Occipital_Fasciculus_L 207 62.323 8.92155 3896
Medial_Lemniscus_R 167 57.1932 8.1491 2983
Inferior_Longitudinal_Fasciculus_L 149 62.3197 7.67076 2880
Corticostriatal_Tract_Superior_R 98 55.2739 6.75859 1983
Corticostriatal_Tract_Posterior_L 83 63.6939 8.10229 3284
Thalamic_Radiation_Posterior_R 79 59.1474 6.56477 2002
Cerebellum_L 75 54.2486 7.18739 2201
Corticospinal_Tract_L 74 59.3102 6.48496 1959
Superior_Longitudinal_Fasciculus2_R 73 57.1082 5.34 1279
Thalamic_Radiation_Posterior_L 67 57.5649 6.86221 2129
Corticostriatal_Tract_Posterior_R 64 58.229 6.87087 2159
Cingulum_Frontal_Parietal_L 62 61.1051 5.84037 1637
Middle_Longitudinal_Fasciculus_R 62 54.7522 6.35008 1734
Cingulum_Frontal_Parietal_R 58 57.013 5.1378 1182
Inferior_Fronto_Occipital_Fasciculus_R 54 55.2686 6.21744 1678
Corticostriatal_Tract_Superior_L 50 53.9601 5.27443 1179
Extreme_Capsule_L 49 59.56 5.9696 1667
Arcuate_Fasciculus_R 40 56.4534 5.1632 1182
Extreme_Capsule_R 40 56.0137 4.54058 907
Corticopontine_Tract_Parietal_R 34 58.8266 5.97962 1652
Middle_Longitudinal_Fasciculus_L 33 56.3185 4.13692 757
Cingulum_Parolfactory_L 31 58.2019 4.34502 863
Medial_Lemniscus_L 30 56.7371 4.62938 955
Dentatorubrothalamic_Tract_R 28 53.5793 5.02364 1062
Corticopontine_Tract_Parietal_L 24 59.4321 5.07032 1200
Thalamic_Radiation_Anterior_R 24 59.1752 4.15147 801
Superior_Longitudinal_Fasciculus1_L 19 56.8632 3.08122 424
Corticostriatal_Tract_Anterior_L 19 54.2121 3.74137 596
Dentatorubrothalamic_Tract_L 19 53.5778 4.12783 717
Cingulum_Parolfactory_R 18 57.7912 2.75298 344
Thalamic_Radiation_Anterior_L 18 55.1118 3.74787 608
Thalamic_Radiation_Superior_R 17 55.1917 3.63259 572
Cingulum_Frontal_Parahippocampal_R 15 58.8151 3.4159 539
Corticopontine_Tract_Occipital_L 11 58.3899 2.53628 295
Corticostriatal_Tract_Anterior_R 11 54.1962 3.5353 532
Anterior_Commissure 11 51.8178 3.15069 404
Corticopontine_Tract_Occipital_R 10 56.62 2.73237 332



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular error rad3 in peri and post menopausal women


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error rad3 in peri and post menopausal women


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error rad3 in peri and post menopausal women




Plots

## [1] "Corticospinal_Tract_R"
## [1] "Corpus_Callosum_Tapetum"
## [1] "Arcuate_Fasciculus_R"
## [1] "Medial_Lemniscus_R"
## [1] "Corticostriatal_Tract_Superior_R"
## [1] "Cingulum_Frontal_Parietal_L"
## [1] "Inferior_Longitudinal_Fasciculus_R"
## [1] "Dentatorubrothalamic_Tract_R"

MD

All subjects

Positive Correlations (FDR = 0.052632)
.
Fornix_L
14
54.0197
3.34248
474



Negative Correlations (FDR = 0.001083)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_R 385 56.2115 7.25851 2326
Fornix_L 359 55.8681 8.22718 2970
Thalamic_Radiation_Superior_L 21 54.4852 3.44885 509



Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop Angular error rad3


Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 in peri and post menopausal women


Glass Brain displaying tracts that had MD positively and negatively correlated with loop angular error rad3 in peri and post menopausal women







Men

Positive Correlations (FDR = 0.052789)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 1565 58.822 9.85954 4491
Fornix_R 252 55.9948 7.25689 2316
Thalamic_Radiation_Superior_L 110 56.39 6.15898 1680
Thalamic_Radiation_Superior_R 11 57.0999 2.44914 269
Corpus_Callosum_Forceps_Major 10 53.2237 3.24436 440
Cerebellum_L 10 52.8089 2.50373 260



Negative Correlations (FDR = 1.000000) Not significant



Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop Angular error rad3 in men


Glass Brain displaying tracts that had MD positively correlated with loop angular error rad3 in peri and post menopausal women







Women

Positive Correlations (FDR = 1.000000) Not significant


Negative Correlations (FDR = 0.000594)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 790 55.9141 9.18768 3707
Fornix_R 298 55.11 6.73613 1964
Corpus_Callosum_Tapetum 112 60.6023 6.4171 1960
Corpus_Callosum_Body 106 57.9578 5.31933 1288
Thalamic_Radiation_Superior_L 78 53.3173 5.43288 1236
Optic_Radiation_L 29 54.8945 3.35399 485
Cingulum_Frontal_Parietal_L 11 54.5619 1.51225 98
Corpus_Callosum_Forceps_Major 10 53.6157 2.34722 232



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 women


Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in women







pre

Positive Correlations (FDR = 1.000000) Not significant


Negative Correlations (FDR = 0.027414)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 593 60.8483 8.51618 3466
Fornix_R 229 57.3531 5.34522 1287
Cerebellum_R 63 54.2347 4.15111 734
Thalamic_Radiation_Superior_L 36 53.8466 3.98621 672
Corpus_Callosum_Body 36 64.507 4.33708 953
Corpus_Callosum_Tapetum 36 59.8425 4.25515 851
Corpus_Callosum_Forceps_Major 31 55.6306 4.18162 764
Cingulum_Frontal_Parietal_L 17 55.0485 1.72734 129



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 pre menopausal women


Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in pre menopausal women







peri

Positive Correlations (FDR = 1.000000) Not significant



Negative Correlations (FDR = 0.018769)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Tapetum 136 61.3216 9.20066 4077
Corpus_Callosum_Forceps_Major 125 61.5881 10.2136 5046
Cerebellum_R 96 54.6717 8.23653 2913
Corpus_Callosum_Body 94 63.0077 8.48647 3564
Fornix_L 89 62.0309 6.68314 2176
Corticostriatal_Tract_Posterior_R 71 56.0654 7.4759 2461
Inferior_Longitudinal_Fasciculus_R 63 62.7407 7.7058 2926
Corpus_Callosum_Forceps_Minor 47 59.0682 6.8029 2147
Cerebellum_L 44 53.5571 6.30093 1670
Arcuate_Fasciculus_R 30 58.1423 5.17726 1224
Inferior_Fronto_Occipital_Fasciculus_L 26 60.3186 5.16947 1266
Inferior_Fronto_Occipital_Fasciculus_R 25 57.9908 4.96774 1124
Arcuate_Fasciculus_L 23 55.6588 4.4714 874
Thalamic_Radiation_Superior_L 23 58.2649 3.96659 720
Fornix_R 23 61.9287 3.69203 663
Dentatorubrothalamic_Tract_L 21 55.6267 4.9396 1066
Middle_Cerebellar_Peduncle 21 63.6313 4.1507 861
Inferior_Longitudinal_Fasciculus_L 19 59.3809 4.15976 807
Dentatorubrothalamic_Tract_R 16 58.7448 3.74475 647
Optic_Radiation_L 14 55.7199 3.83613 644
Anterior_Commissure 14 57.5897 3.66635 608
Corticostriatal_Tract_Posterior_L 13 57.4001 3.65424 602
Thalamic_Radiation_Posterior_R 11 54.8985 3.79813 622
Reticular_Tract_L 11 64.9192 2.82183 406
Cingulum_Frontal_Parietal_L 10 61.3974 2.95475 421
Superior_Longitudinal_Fasciculus2_L 10 59.0103 3.38803 532
Corticospinal_Tract_L 10 53.4043 3.26818 448



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 peri menopausal women


Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in peri menopausal women







post

Positive Correlations (FDR = 1.000000)

No Significant Findings



Negative Correlations (FDR = 0.289057)

No Significant Findings

Peri + Post

Positive Correlations (FDR = 1.000000)

No Significant Findings



Negative Correlations (FDR = 0.187319)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 923 57.9248 10.231 4762
Corpus_Callosum_Tapetum 860 60.3349 12.8388 7811
Fornix_R 305 56.5731 7.42714 2451
Cerebellum_R 143 53.405 7.3744 2281
Corpus_Callosum_Body 124 59.1681 7.52153 2629
Thalamic_Radiation_Superior_L 115 58.4374 6.05373 1682
Corpus_Callosum_Forceps_Major 114 58.4289 7.64203 2680
Inferior_Longitudinal_Fasciculus_R 45 56.8591 5.2503 1231
Inferior_Fronto_Occipital_Fasciculus_L 31 54.8414 4.20885 763
Corticostriatal_Tract_Posterior_R 23 54.7086 4.0073 690
Inferior_Longitudinal_Fasciculus_L 20 53.5151 3.94463 654
Cingulum_Frontal_Parietal_L 16 55.1192 2.81892 344
Cingulum_Frontal_Parahippocampal_L 15 62.6689 3.68674 669
Middle_Cerebellar_Peduncle 15 53.2047 2.78883 325
Arcuate_Fasciculus_L 13 56.4665 2.93872 383
Optic_Radiation_L 10 54.6088 2.7485 324



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error rad3 peri and post menopausal women

Glass Brain displaying tracts that had MD negatively correlated with loop angular error rad3 in peri and post menopausal women







Plots

## [1] "Fornix_L"
## [1] "Fornix_R"
## [1] "Thalamic_Radiation_Superior_L"
## [1] "Corpus_Callosum_Forceps_Major"

RD

All subjects

Positive Correlations (FDR = 0.050000)
V1 V2 V3
Tract Name Fornix_L NA
number of tracts 14 NA
mean length(mm) 53.7203 NA
span(mm) 19.8139 NA
curl 2.71124 NA
elongation 17.6467 NA
diameter(mm) 3.04421 NA
volume(mm^3) 391 NA
trunk volume(mm^3) 356 NA
branch volume(mm^3) 35 NA
total surface area(mm^2) 1644 NA
total radius of end regions(mm) 3.98723 NA
total area of end regions(mm^2) 20 NA
irregularity 3.19992 NA
area of end region 1(mm^2) 10 NA
radius of end region 1(mm) 1.57332 NA
irregularity of end region 1 0.777652 NA
area of end region 2(mm^2) 10 NA
radius of end region 2(mm) 2.41391 NA
irregularity of end region 2 1.83059 NA
qa 0.165968 NA
inc_t 0.0694185 NA
dec_t 0.584835 NA
qa_map 0.167843 NA
ICBM152_adult.T1W 181.584 NA
ICBM152_adult.WM 70.7534 NA



Negative Correlations (FDR = 0.000506)
V1 V2 V3 V4 V5
Tract Name Fornix_R Fornix_L Thalamic_Radiation_Superior_L NA
number of tracts 389 361 16 NA
mean length(mm) 55.8954 56.3367 53.3834 NA
span(mm) 24.0949 21.6483 12.4267 NA
curl 2.3198 2.60236 4.29585 NA
elongation 8.16567 7.06055 18.7739 NA
diameter(mm) 6.84517 7.97908 2.84349 NA
volume(mm^3) 2057 2817 339 NA
trunk volume(mm^3) 1230 2308 149 NA
branch volume(mm^3) 827 509 190 NA
total surface area(mm^2) 6734 7792 2337 NA
total radius of end regions(mm) 12.9366 11.7828 11.5205 NA
total area of end regions(mm^2) 364 404 23 NA
irregularity 5.60226 5.51766 4.90062 NA
area of end region 1(mm^2) 175 199 12 NA
radius of end region 1(mm) 7.03241 5.94405 6.47763 NA
irregularity of end region 1 0.88781 0.557779 10.985 NA
area of end region 2(mm^2) 189 205 11 NA
radius of end region 2(mm) 5.90415 5.83879 5.04285 NA
irregularity of end region 2 0.579433 0.522446 7.26289 NA
qa 0.136099 0.15389 0.183768 NA
inc_t 0.0306706 0.0570189 0.0282008 NA
dec_t 1.38082 0.869079 0.787288 NA
qa_map 0.138295 0.155717 0.186727 NA
ICBM152_adult.T1W 144.679 171.739 183.31 NA
ICBM152_adult.WM 32.6306 61.603 103.381 NA



Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3


Glass Brain displaying tracts that had AD positively and negatively correlated with loop angular error rad3 in women


Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3







Men

Positive Correlations (FDR = 0.040025)
V1 V2 V3 V4 V5 V6
Tract Name Fornix_L Fornix_R Thalamic_Radiation_Superior_L Corpus_Callosum_Forceps_Major NA
number of tracts 1041 133 60 11 NA
mean length(mm) 59.0382 56.5103 55.3754 51.8294 NA
span(mm) 20.8984 21.9502 17.0923 21.6841 NA
curl 2.825 2.57448 3.23979 2.3902 NA
elongation 6.7454 10.0082 10.6765 16.5548 NA
diameter(mm) 8.75236 5.64637 5.18668 3.13079 NA
volume(mm^3) 3552 1415 1170 399 NA
trunk volume(mm^3) 2898 1056 239 236 NA
branch volume(mm^3) 654 359 931 163 NA
total surface area(mm^2) 9658 5611 5233 2513 NA
total radius of end regions(mm) 14.031 9.20754 10.799 6.57739 NA
total area of end regions(mm^2) 717 161 81 17 NA
irregularity 5.94948 5.59749 5.79955 4.92961 NA
area of end region 1(mm^2) 382 72 35 8 NA
radius of end region 1(mm) 7.3392 4.32519 5.99898 3.33909 NA
irregularity of end region 1 0.44298 0.816257 3.23025 4.3784 NA
area of end region 2(mm^2) 335 89 46 9 NA
radius of end region 2(mm) 6.69183 4.88235 4.8 3.23831 NA
irregularity of end region 2 0.419947 0.84143 1.57353 3.66052 NA
qa 0.146411 0.124726 0.164339 0.251602 NA
inc_t 0.894854 0.602643 0.742176 0.816685 NA
dec_t 0.0399168 0.223773 0.07149 0.193942 NA
qa_map 0.148177 0.126486 0.166319 0.254561 NA
ICBM152_adult.T1W 174.794 172.162 186.69 168.626 NA
ICBM152_adult.WM 61.9906 50.0898 116.918 111.357 NA



Negative Correlations (FDR = 1.000000)

Not significant



Figures

Slice overlay image displaying ROIs with tracts that had RD positively correlated with loop Angular error rad3 in men


Glass Brain displaying tracts that had RD positively correlated with loop angular error rad3 in men







Women

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.000631)
V1 V2 V3 V4 V5 V6 V7 V8
Tract Name Fornix_L Fornix_R Corpus_Callosum_Body Corpus_Callosum_Tapetum Thalamic_Radiation_Superior_L Cingulum_Frontal_Parietal_L NA
number of tracts 803 324 77 56 50 17 NA
mean length(mm) 56.0847 54.8724 54.1434 59.6825 53.7264 54.8275 NA
span(mm) 21.7578 23.581 20.6704 21.9326 14.5498 24.0448 NA
curl 2.57768 2.32698 2.61936 2.72118 3.69259 2.28022 NA
elongation 6.04314 8.11601 9.8456 12.3596 11.5693 35.1114 NA
diameter(mm) 9.28072 6.761 5.49924 4.82883 4.64389 1.56153 NA
volume(mm^3) 3794 1970 1286 1093 910 105 NA
trunk volume(mm^3) 3430 1495 533 134 271 70 NA
branch volume(mm^3) 364 475 753 959 639 35 NA
total surface area(mm^2) 9829 6485 6799 5771 4348 820 NA
total radius of end regions(mm) 13.357 12.9792 17.7545 31.4854 13.985 4.8142 NA
total area of end regions(mm^2) 708 331 113 83 71 17 NA
irregularity 6.01082 5.5641 7.26854 6.37401 5.54715 3.0487 NA
area of end region 1(mm^2) 350 168 53 45 35 7 NA
radius of end region 1(mm) 7.11935 7.11319 8.62274 19.4092 7.11512 2.33479 NA
irregularity of end region 1 0.454948 0.946172 4.40722 26.2998 4.54409 2.44652 NA
area of end region 2(mm^2) 358 163 60 38 36 10 NA
radius of end region 2(mm) 6.23762 5.86602 9.1318 12.0762 6.86992 2.47941 NA
irregularity of end region 2 0.341432 0.663207 4.36628 12.0566 4.11861 1.93129 NA
qa 0.154405 0.136414 0.278221 0.25252 0.167394 0.122222 NA
inc_t 0.0216797 0.0286679 0.0360744 0.0419393 0.0292107 0.00748792 NA
dec_t 1.40691 1.33244 1.33789 1.11083 1.45159 1.28391 NA
qa_map 0.156275 0.138524 0.284104 0.255761 0.169933 0.125605 NA
ICBM152_adult.T1W 169.005 147.855 177.519 164.89 177.756 198.015 NA
ICBM152_adult.WM 60.1516 35.3153 124.768 90.4514 100.88 128.423 NA



Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in women


Glass Brain displaying tracts that had RD positively and negatively correlated with loop angular error rad3 in women







pre

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.030260)
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10
Tract Name Fornix_L Fornix_R Corpus_Callosum_Tapetum Corpus_Callosum_Body Corpus_Callosum_Forceps_Major Cerebellum_R Thalamic_Radiation_Superior_L Cingulum_Frontal_Parietal_L NA
number of tracts 637 258 36 30 29 28 18 13 NA
mean length(mm) 60.8372 57.824 58.8379 63.9396 58.9119 53.5071 54.2306 52.9322 NA
span(mm) 22.4441 24.2811 22.3727 16.0202 24.9094 24.4108 11.9267 23.4392 NA
curl 2.71061 2.38145 2.62989 3.99118 2.36505 2.19194 4.547 2.25828 NA
elongation 6.91911 9.98849 14.5565 16.8163 13.8347 15.9153 17.8759 28.5402 NA
diameter(mm) 8.79263 5.78906 4.04203 3.80223 4.25828 3.36199 3.03372 1.85465 NA
volume(mm^3) 3694 1522 755 726 839 475 392 143 NA
trunk volume(mm^3) 2403 498 257 122 89 139 189 73 NA
branch volume(mm^3) 1291 1024 498 604 750 336 203 70 NA
total surface area(mm^2) 12602 6362 4439 4361 4769 3294 2602 1128 NA
total radius of end regions(mm) 18.6486 12.6007 19.5674 18.5539 12.5027 13.7018 14.2387 5.13462 NA
total area of end regions(mm^2) 552 220 54 51 42 34 29 15 NA
irregularity 7.49897 6.04961 5.94125 5.70989 6.05118 5.82863 5.03428 3.65743 NA
area of end region 1(mm^2) 284 101 27 26 21 15 14 9 NA
radius of end region 1(mm) 10.2093 6.84982 8.56332 8.56849 5.5854 6.68516 5.31325 2.18491 NA
irregularity of end region 1 1.15298 1.45944 8.5324 8.87125 4.66701 9.36014 6.33494 1.66638 NA
area of end region 2(mm^2) 268 119 27 25 21 19 15 6 NA
radius of end region 2(mm) 8.43929 5.7509 11.0041 9.98541 6.91727 7.01665 8.92541 2.94971 NA
irregularity of end region 2 0.834885 0.873121 14.0895 12.5297 7.15814 8.1406 16.6846 4.55573 NA
qa 0.169252 0.151158 0.281925 0.25991 0.274995 0.123909 0.195785 0.119879 NA
inc_t 0.0302541 0.0245192 0.0983148 0.0675797 0.210173 0.0345652 0.0552861 0.0343937 NA
dec_t 1.79158 2.47154 1.51705 1.73972 1.06367 1.51339 1.72566 1.80816 NA
qa_map 0.171595 0.153053 0.28521 0.263838 0.277901 0.125022 0.199441 0.122567 NA
ICBM152_adult.T1W 169.267 162.082 166.202 176.022 173.879 172.678 191.628 196.58 NA
ICBM152_adult.WM 60.4165 50.6869 109.101 118.57 128.857 30.6746 128.135 122.882 NA



Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in pre-menopausal women


Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3 in pre-menopausalwomen







peri

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.017967)
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11 V12 V13 V14 V15 V16 V17 V18 V19 V20 V21
Tract Name Corpus_Callosum_Body Corpus_Callosum_Forceps_Major Corpus_Callosum_Tapetum Fornix_L Cerebellum_R Corpus_Callosum_Forceps_Minor Cerebellum_L Fornix_R Inferior_Longitudinal_Fasciculus_R Thalamic_Radiation_Posterior_R Corticostriatal_Tract_Posterior_R Dentatorubrothalamic_Tract_L Arcuate_Fasciculus_R Thalamic_Radiation_Superior_L Middle_Cerebellar_Peduncle Reticular_Tract_R Reticular_Tract_L Cingulum_Parolfactory_R Corticospinal_Tract_L NA
number of tracts 128 102 98 94 68 63 52 26 25 22 19 19 16 15 14 13 12 10 10 NA
mean length(mm) 60.2305 60.6943 61.7859 62.3784 54.0638 57.4765 53.2363 59.4028 60.0235 54.6439 53.2758 57.056 55.5145 63.0769 60.8666 57.087 62.4961 65.8215 57.4239 NA
span(mm) 21.9182 23.7235 23.7322 20.9358 25.0929 21.1464 24.5342 25.0968 25.5671 25.244 22.8764 25.0887 21.6387 19.8764 22.4672 23.8772 25.9041 30.6326 27.955 NA
curl 2.74796 2.5584 2.60347 2.97951 2.15454 2.71803 2.16988 2.36694 2.34769 2.16463 2.32885 2.27417 2.56552 3.17346 2.70913 2.39086 2.4126 2.14874 2.05415 NA
elongation 6.12991 6.64491 7.54752 9.52541 7.01647 7.74827 7.54064 17.2075 11.7942 11.4177 10.8064 13.7286 13.1252 17.2292 16.2705 17.6133 19.1458 30.9377 21.0385 NA
diameter(mm) 9.82567 9.13395 8.18626 6.54864 7.70528 7.41798 7.05992 3.45215 5.08923 4.78587 4.93004 4.15599 4.2296 3.66104 3.74092 3.24113 3.26422 2.12755 2.72947 NA
volume(mm^3) 4567 3977 3252 2101 2521 2484 2084 556 1221 983 1017 774 780 664 669 471 523 234 336 NA
trunk volume(mm^3) 0 0 108 107 180 0 0 86 0 0 62 113 64 0 64 73 0 93 0 NA
branch volume(mm^3) 4567 3977 3144 1994 2341 2484 2084 470 1221 983 955 661 716 664 605 398 523 141 336 NA
total surface area(mm^2) 31708 22905 20361 9712 14805 14030 11398 3114 8173 6796 7273 5540 5205 4583 5029 2870 3496 1775 2632 NA
total radius of end regions(mm) 39.2324 30.1747 39.6365 17.3276 17.3715 21.6114 10.7249 10.1279 25.071 18.982 17.3667 47.4258 18.4517 19.4574 20.8431 21.9931 42.189 13.5979 12.3994 NA
total area of end regions(mm^2) 210 175 151 126 106 104 87 35 45 40 37 31 30 25 25 21 18 15 18 NA
irregularity 17.0545 13.1514 12.8137 7.56787 11.3126 10.4745 9.65319 4.83363 8.51644 8.27182 8.81421 7.43676 7.05611 6.31722 7.0303 4.93739 5.45493 4.03461 5.34521 NA
area of end region 1(mm^2) 105 90 75 69 49 53 42 19 23 19 19 16 15 14 12 9 9 6 10 NA
radius of end region 1(mm) 18.0721 19.3852 25.1322 10.9873 7.03918 11.2517 4.64161 4.88337 12.5748 9.642 10.3605 27.4742 8.138 12.9941 8.82004 12.7431 25.0791 6.06787 4.67343 NA
irregularity of end region 1 9.77191 13.1175 26.4576 5.49649 3.17686 7.50428 1.61153 3.94308 21.5986 15.372 17.7484 148.211 13.8706 37.8892 20.3662 56.6834 219.549 19.2784 6.86153 NA
area of end region 2(mm^2) 105 85 76 57 57 51 45 16 22 21 18 15 15 11 13 12 9 9 8 NA
radius of end region 2(mm) 21.1603 10.7895 14.5042 6.34026 10.3323 10.3597 6.08324 5.2445 12.4962 9.34001 7.00617 19.9516 10.3137 6.46332 12.023 9.24998 17.1099 7.53001 7.72593 NA
irregularity of end region 2 13.3969 4.3026 8.69611 2.21559 5.88398 6.61116 2.58349 5.40055 22.2989 13.0504 8.56719 83.371 22.2786 11.9308 34.933 22.4001 102.188 19.7924 23.4402 NA
qa 0.263052 0.285966 0.253793 0.152229 0.113225 0.241646 0.126245 0.144512 0.232488 0.226512 0.202426 0.24162 0.224804 0.158737 0.221471 0.172261 0.17946 0.176172 0.297009 NA
inc_t 0.157746 0.194091 0.149995 0.151021 0.22574 0.236622 0.397456 0.208797 0.213121 0.207203 0.205429 0.256298 0.182706 0.0731557 0.367053 0.201515 0.32213 0.263596 0.250786 NA
dec_t 1.2437 1.02577 1.11665 1.04612 1.17011 1.13634 0.786282 0.716828 0.980037 0.96233 1.05725 0.858782 1.01517 1.06153 0.773196 0.965973 0.827268 0.763737 0.97458 NA
qa_map 0.268414 0.289726 0.257294 0.154285 0.114205 0.245553 0.127598 0.146382 0.236634 0.230647 0.205934 0.243815 0.227658 0.161836 0.227396 0.174315 0.181617 0.186053 0.299365 NA
ICBM152_adult.T1W 198.016 205.917 179.983 175.385 175.219 219.549 161.21 148.074 223.317 220.399 219.397 197.159 226.499 184.913 215.801 163.96 163.308 174.226 213.007 NA
ICBM152_adult.WM 188.693 207.294 139.073 73.4995 49.8151 235.947 20.4462 35.9977 249.029 235.689 232.694 161.576 250.869 111.683 233.779 77.7218 77.2735 82.2829 236.724 NA



Figures

Slice overlay image displaying ROIs with tracts that had RD negatively correlated with loop angular error rad3 in perimenopausal women


Glass Brain displaying tracts that had RD negatively correlated with loop angular error rad3 in peri menopausal women







post

Positive Correlations (FDR = 1.000000) No Significant Findings



Negative Correlations (FDR = 0.273451)

No Significant Findings







Peri + Post

Positive Correlations (FDR = 1.000000)

No significant



Negative Correlations (FDR = 0.231903)

No significant







Loop Angular error average

QA

All subjects

Positive Correlations (FDR = 0.001274)
.
Corpus_Callosum_Forceps_Minor
526
54.6692
10.5963
4821



Negative Correlations (FDR= 0.009901)

Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corticospinal_Tract_R 103 54.0583 6.05964 1559
Corpus_Callosum_Forceps_Major 30 56.5333 4.0603 732
Cerebellum_R 24 52.5 3.76985 586
Medial_Lemniscus_R 20 55 3.50607 531
Arcuate_Fasciculus_L 15 53.6 3.57158 537
Cingulum_Frontal_Parietal_L 12 52.6667 2.36316 231



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop Angular Error average


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop Angular Error average


Glass Brain displaying tracts that had QA positively and negatively correlated with loop Angular Error average





Men

Positive Correlations (FDR =0.249739)

not significant



Negative Correlations (FDR =0.038326)

Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Cerebellum_L 897 53.5295 15.2894 9828
Corpus_Callosum_Forceps_Major 330 59.697 8.26011 3199
Cerebellum_R 263 53.3308 9.28881 3614
Corpus_Callosum_Tapetum 77 58.9091 5.70148 1504
Vermis 64 52.7812 5.23716 1137
Arcuate_Fasciculus_L 26 57.6154 4.27761 828
Cingulum_Frontal_Parietal_R 6 53.6667 2.1783 200



Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average


Glass Brain displaying tracts that had QA negatively correlated with loop angular error average




Women

Positive Correlations (FDR =0.009950)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 62 52.3548 6.58864 1785
Cerebellum_L 57 53.9298 4.75083 956
Corpus_Callosum_Forceps_Major 25 55.2 3.92237 667



Negative Correlations (FDR = 0.001003)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corticospinal_Tract_R 611 56.3011 10.0261 4445
Medial_Lemniscus_R 278 57.0647 7.33297 2410
Corticostriatal_Tract_Superior_R 61 53.9344 5.36443 1219
Dentatorubrothalamic_Tract_R 55 52.2545 5.39606 1195
Cingulum_Frontal_Parietal_L 44 53.5455 3.36432 476
Corpus_Callosum_Tapetum 43 52.5581 5.31477 1166
Arcuate_Fasciculus_R 37 54.3784 3.81011 620
Corticospinal_Tract_L 29 56 4.65243 952
Corpus_Callosum_Body 29 54.8276 4.91678 1041
Corpus_Callosum_Forceps_Major 29 55.8621 3.74703 616
Extreme_Capsule_R 21 54.8571 2.88257 358
Inferior_Fronto_Occipital_Fasciculus_L 12 52.1667 2.62816 283
Extreme_Capsule_L 10 53.2 2.58868 280



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop angular error average


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average









pre

Positive Correlations (FDR = 0.057417)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Major 771 62.4971 11.3668 6342
Corpus_Callosum_Tapetum 478 54.7222 11.6298 5813
Corpus_Callosum_Body 402 60.5216 9.15962 3988
Cerebellum_L 302 56.325 8.817 3439
Corpus_Callosum_Forceps_Minor 169 58.1751 6.87565 2160
Fornix_L 82 56.7185 4.75689 1008
Inferior_Longitudinal_Fasciculus_L 73 58.3937 6.6792 2046
Arcuate_Fasciculus_L 61 54.697 3.93741 666
Inferior_Fronto_Occipital_Fasciculus_L 47 54.697 5.81576 1453
Fornix_R 35 53.7272 3.21809 437
Corticostriatal_Tract_Posterior_L 24 52.5179 4.4939 833
Inferior_Longitudinal_Fasciculus_R 15 52.2904 3.35764 463
Thalamic_Radiation_Posterior_L 12 52.3479 3.08385 391
Cerebellum_R 11 57.0929 2.82162 357



Negative Correlations (FDR = 0.019934)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Inferior_Fronto_Occipital_Fasciculus_R 597 69.1472 10.6277 6134
Middle_Cerebellar_Peduncle 351 59.2899 11.2905 5936
Corticospinal_Tract_L 332 59.9263 11.7028 6446
Corticospinal_Tract_R 325 63.6286 9.38223 4399
Cerebellum_L 218 56.8343 8.17616 2984
Inferior_Fronto_Occipital_Fasciculus_L 205 60.002 7.07666 2360
Corpus_Callosum_Tapetum 170 64.3293 8.57492 3715
Corticostriatal_Tract_Superior_L 153 56.2031 8.85602 3462
Cingulum_Frontal_Parietal_L 150 57.1294 6.42112 1850
Arcuate_Fasciculus_R 132 65.6466 7.61398 2989
Cingulum_Frontal_Parietal_R 128 58.7267 7.0462 2290
Corpus_Callosum_Body 124 61.256 8.95492 3858
Medial_Lemniscus_L 117 59.0155 6.94246 2234
Vermis 93 54.8679 6.50948 1826
Dentatorubrothalamic_Tract_L 88 58.6704 7.99852 2948
Cingulum_Parolfactory_R 83 65.7486 4.14685 888
Inferior_Longitudinal_Fasciculus_R 83 60.2585 6.47302 1983
Medial_Lemniscus_R 80 57.9821 6.59054 1978
Dentatorubrothalamic_Tract_R 79 62.4662 7.14556 2505
Superior_Longitudinal_Fasciculus2_R 76 56.1198 6.58112 1909
Arcuate_Fasciculus_L 70 61.0098 4.92234 1161
Superior_Longitudinal_Fasciculus2_L 56 56.6153 5.97228 1586
Uncinate_Fasciculus_R 54 55.2688 4.38327 834
Corticopontine_Tract_Parietal_L 49 69.6075 4.75484 1236
Corpus_Callosum_Forceps_Major 33 60.6761 4.62643 1020
Corticopontine_Tract_Parietal_R 28 64.2252 4.91793 1220
Frontal_Aslant_Tract_L 24 66.2587 4.96338 1282
Extreme_Capsule_L 22 60.2918 4.26162 860
Uncinate_Fasciculus_L 18 60.2331 2.94035 409
Cingulum_Frontal_Parahippocampal_L 17 55.0528 3.47457 522
Superior_Longitudinal_Fasciculus1_R 17 52.5971 3.07654 391
Corticostriatal_Tract_Superior_R 13 57.0858 3.64292 595
Cingulum_Frontal_Parahippocampal_R 12 56.3262 3.02944 406
Reticular_Tract_R 10 59.6128 2.27349 242



Figures

Slice overlay image displaying ROIs with tracts that had QA positively correlated with loop angular error average


Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average









peri

Positive Correlations (FDR =0.530855)

Not significant

Negative Correlations (FDR = 0.010149)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Body 317 65.6593 15.7849 12849
Cerebellum_L 260 55.7538 14.3523 9020
Corpus_Callosum_Tapetum 213 63.8592 12.3744 7680
Inferior_Fronto_Occipital_Fasciculus_R 199 63.4271 10.7688 5777
Middle_Cerebellar_Peduncle 183 61.5956 12.0152 6984
Cerebellum_R 178 54.573 13.2554 7531
Corpus_Callosum_Forceps_Major 176 61.0909 11.5367 6386
Arcuate_Fasciculus_R 169 68.5562 9.87911 5255
Superior_Longitudinal_Fasciculus2_R 160 64.6 10.2543 5335
Corticospinal_Tract_R 139 65.7698 9.72465 4885
Cingulum_Frontal_Parietal_R 123 65.8211 7.8443 3181
Arcuate_Fasciculus_L 121 58.1322 10.468 5003
Corticostriatal_Tract_Posterior_R 113 65.4513 9.08837 4246
Inferior_Longitudinal_Fasciculus_L 96 61.7292 8.74894 3711
Inferior_Longitudinal_Fasciculus_R 90 61.2889 9.43715 4287
Inferior_Fronto_Occipital_Fasciculus_L 85 63.3882 8.40976 3521
Dentatorubrothalamic_Tract_R 79 59.9494 9.3849 4147
Medial_Lemniscus_R 77 64.1299 7.57878 2893
Superior_Longitudinal_Fasciculus2_L 76 60.2895 8.54692 3459
Corticostriatal_Tract_Posterior_L 70 62.2286 8.46966 3506
Frontal_Aslant_Tract_L 64 60.6562 7.9316 2997
Dentatorubrothalamic_Tract_L 63 58.4762 8.37584 3222
Corticostriatal_Tract_Superior_L 58 56.6207 7.71078 2644
Medial_Lemniscus_L 58 58.2069 6.57448 1976
Corticospinal_Tract_L 56 60.6786 7.35636 2579
Cingulum_Frontal_Parietal_L 53 60.7547 6.39595 1952
Corticopontine_Tract_Parietal_R 50 61.92 6.65368 2153
Thalamic_Radiation_Posterior_R 50 61.32 6.51311 2043
Vermis 49 55.3469 6.68739 1944
Corpus_Callosum_Forceps_Minor 44 57.3636 7.05746 2244
Cingulum_Parahippocampal_Parietal_R 37 57.2432 5.45329 1337
Corticostriatal_Tract_Superior_R 36 61.3889 6.49669 2035
Superior_Longitudinal_Fasciculus1_R 32 66.9375 5.18248 1412
Optic_Radiation_L 30 55.3333 4.90834 1047
Anterior_Commissure 30 65.6667 5.1521 1369
Corticopontine_Tract_Parietal_L 29 68.6897 5.50514 1635
Extreme_Capsule_R 27 63.1852 5.15549 1319
Thalamic_Radiation_Anterior_R 26 63.5385 4.99082 1243
Cingulum_Parolfactory_R 25 67.36 4.19497 931
Superior_Longitudinal_Fasciculus3_R 23 61.6522 4.78356 1108
Extreme_Capsule_L 22 60.2727 4.80293 1092
Thalamic_Radiation_Posterior_L 20 56.2 5.21842 1202
Parietal_Aslant_Tract_L 19 57.0526 4.80836 1036
Reticular_Tract_R 19 63.4737 4.88986 1192
Middle_Longitudinal_Fasciculus_R 18 58.3333 4.61789 977
Superior_Longitudinal_Fasciculus3_L 18 57.5556 4.45955 899
Parietal_Aslant_Tract_R 15 55.4667 3.88939 659
Corticopontine_Tract_Frontal_R 15 60.8 4.70924 1059
Corticopontine_Tract_Occipital_R 13 64.4615 3.38177 579
Thalamic_Radiation_Superior_R 13 61.3846 4.28931 887
Frontal_Aslant_Tract_R 12 53.3333 3.92406 645
Fornix_R 12 69.8333 3.07318 518
Middle_Longitudinal_Fasciculus_L 11 55.8182 3.80287 634
Reticular_Tract_L 10 60.4 3.75254 668



Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average


Glass Brain displaying tracts that had QA positively and negatively correlated with loop angular error average









post

Positive Correlations (FDR= 1.000000)



Negative Correlations (FDR =0.129906)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Body 2830 69.711 27.605 41722
Corpus_Callosum_Forceps_Minor 1108 68.9404 17.8293 17212
Corpus_Callosum_Forceps_Major 1068 78.3296 16.4186 16584
Arcuate_Fasciculus_L 790 71.4228 15.1864 12937
Corpus_Callosum_Tapetum 637 67.0769 16.063 13593
Cerebellum_R 536 57.6604 17.0805 13212
Corticospinal_Tract_R 383 65.0653 11.6721 6962
Inferior_Longitudinal_Fasciculus_L 284 68.6127 11.8624 7583
Inferior_Fronto_Occipital_Fasciculus_L 273 71.6337 11.4686 7400
Superior_Longitudinal_Fasciculus2_L 270 62.6889 12.4429 7623
Cingulum_Frontal_Parietal_L 264 69.7879 9.97979 5459
Middle_Cerebellar_Peduncle 263 60.4411 12.9273 7933
Inferior_Fronto_Occipital_Fasciculus_R 257 70.5214 11.2741 7040
Dentatorubrothalamic_Tract_R 231 61.6537 12.4735 7534
Cerebellum_L 220 55.3455 13.0502 7403
Medial_Lemniscus_R 219 63.8539 10.1198 5136
Corticostriatal_Tract_Posterior_L 215 67.8233 10.7772 6187
Corticospinal_Tract_L 176 62.3864 10.9854 5913
Dentatorubrothalamic_Tract_L 176 60.1364 11.8756 6661
Corticostriatal_Tract_Posterior_R 173 59.896 10.7061 5392
Cingulum_Frontal_Parietal_R 171 65.6491 9.32241 4481
Corticostriatal_Tract_Superior_L 156 58.9359 10.9647 5565
Extreme_Capsule_L 148 66.7703 8.98012 4229
Medial_Lemniscus_L 146 63.7123 9.13532 4176
Inferior_Longitudinal_Fasciculus_R 144 60.25 11.2641 6004
Superior_Longitudinal_Fasciculus2_R 144 60.7639 11.409 6212
Frontal_Aslant_Tract_L 131 64.626 10.3564 5444
Corticostriatal_Tract_Superior_R 128 58.9219 9.61024 4274
Parietal_Aslant_Tract_L 122 60.1803 7.56644 2706
Arcuate_Fasciculus_R 110 60.8727 8.92701 3810
Thalamic_Radiation_Posterior_L 106 60.5283 8.47437 3414
Middle_Longitudinal_Fasciculus_L 97 62.3918 7.7996 2981
Middle_Longitudinal_Fasciculus_R 93 64.7957 7.08145 2552
Thalamic_Radiation_Anterior_R 90 64.1778 8.57 3702
Frontal_Aslant_Tract_R 74 60.7568 8.1852 3197
Corticopontine_Tract_Parietal_R 70 66.4 6.58302 2260
Superior_Longitudinal_Fasciculus3_L 67 65.1642 7.1794 2638
Corticopontine_Tract_Parietal_L 65 65.0154 7.03059 2524
Extreme_Capsule_R 63 63.4603 6.45539 2077
Thalamic_Radiation_Posterior_R 61 62.4262 7.14071 2500
Superior_Longitudinal_Fasciculus1_L 56 63 5.97082 1764
Thalamic_Radiation_Anterior_L 53 59.6981 7.09465 2360
Superior_Longitudinal_Fasciculus3_R 50 58.88 6.82011 2151
Thalamic_Radiation_Superior_L 50 63.88 7.58571 2887
Parietal_Aslant_Tract_R 49 56.3265 6.26431 1736
Superior_Longitudinal_Fasciculus1_R 48 57.7917 5.92978 1596
Thalamic_Radiation_Superior_R 48 62.8333 6.95628 2388
Reticular_Tract_R 48 61.7917 6.83615 2268
Fornix_L 44 58.4091 6.71576 2069
Cingulum_Parolfactory_R 43 65.0233 4.77621 1165
Uncinate_Fasciculus_R 40 67.25 4.99725 1319
Reticular_Tract_L 39 59.0256 5.71476 1514
Cingulum_Parahippocampal_Parietal_R 38 61.7895 4.97058 1199
Corticostriatal_Tract_Anterior_R 35 54.4 6.3706 1734
Corticostriatal_Tract_Anterior_L 32 55 6.21773 1670
Cingulum_Frontal_Parahippocampal_L 30 69.8 5.32075 1552
Cingulum_Parolfactory_L 26 58.6154 5.13098 1212
Anterior_Commissure 26 58.3846 5.48388 1379
Superior_Cerebellar_Peduncle 26 58 4.48669 917
Cingulum_Parahippocampal_Parietal_L 24 57.4167 4.49218 910
Fornix_R 22 58.6364 3.43693 544
Cingulum_Frontal_Parahippocampal_R 16 61 3.36349 542
Corticopontine_Tract_Occipital_R 14 66 3.65109 691
Inferior_Cerebellar_Peduncle_L 14 55.2857 3.31442 477
Corticopontine_Tract_Occipital_L 12 59.5 3.53208 583
Corticopontine_Tract_Frontal_L 10 55.8 3.5329 547
Optic_Radiation_L 10 52.6 3.61542 540



Figures

Slice overlay image displaying ROIs with tracts that had QA negatively correlated with loop angular error average


Glass Brain displaying tracts that had QA negatively correlated with loop angular error average









Peri and Post

Positive Correlations (FDR =0.007092)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Forceps_Minor 226 56.0531 8.72584 3352
Middle_Cerebellar_Peduncle 43 55.5814 5.07201 1123
Inferior_Longitudinal_Fasciculus_R 19 53.0526 3.23478 436
Cingulum_Parolfactory_L 16 54.875 2.05496 182
Inferior_Fronto_Occipital_Fasciculus_R 12 52.3333 3.45978 492
Corpus_Callosum_Body 11 54.1818 3.18986 433
Cingulum_Parolfactory_R 10 54.8 1.73795 130



Negative Correlations (FDR = 0.000492)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Body 507 64.2485 13.5714 9294
Corpus_Callosum_Tapetum 192 58.7083 8.84828 3610
Corpus_Callosum_Forceps_Major 184 64.9891 8.24754 3472
Arcuate_Fasciculus_L 130 60.2923 6.99348 2316
Corticospinal_Tract_R 60 57.4667 6.11371 1687
Corpus_Callosum_Forceps_Minor 53 58.2642 5.99931 1647
Medial_Lemniscus_R 49 56.3673 5.05667 1132
Corticostriatal_Tract_Superior_R 31 53.6129 4.57153 880
Thalamic_Radiation_Posterior_L 31 54.9032 4.20372 762
Cerebellum_R 25 52.88 3.66873 559
Superior_Longitudinal_Fasciculus2_R 20 54.4 3.25974 454
Parietal_Aslant_Tract_L 17 56.8235 2.62704 308
Corticostriatal_Tract_Posterior_L 17 60.5882 4.26353 865
Cingulum_Frontal_Parietal_R 15 52.9333 3.0863 396
Cingulum_Parolfactory_L 15 55.3333 2.00095 174
Inferior_Fronto_Occipital_Fasciculus_R 14 53.8571 3.04422 392
Inferior_Longitudinal_Fasciculus_L 14 56.4286 3.12572 433
Cingulum_Parolfactory_R 13 53.5385 2.80567 331
Cerebellum_L 13 51.8461 2.94431 353
Extreme_Capsule_R 12 52.8333 3.0102 376
Extreme_Capsule_L 11 55.4545 3.31284 478
Inferior_Fronto_Occipital_Fasciculus_L 11 56 3.06062 412
Corticostriatal_Tract_Posterior_R 11 50.7273 3.3043 435



Figures








<b

Plots

MD

All subjects

Positive Correlations (FDR =0.494235)

Not Significant

Negative Correlations (FDR = 0.211694)

Not significant







Men

Positive Correlations (FDR = 0.012952)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 1963 58.0856 10.7612 5283
Fornix_R 310 55.1097 7.86733 2679
Thalamic_Radiation_Superior_L 198 55.2525 7.42592 2393
Corpus_Callosum_Forceps_Major 148 58.7297 6.05477 1691
Cerebellum_L 38 52.5263 3.67776 558
Thalamic_Radiation_Posterior_L 21 53.7143 3.92826 651
Thalamic_Radiation_Superior_R 13 55.6923 2.61453 299



Negative Correlations (FDR = 0.842857)

Not significant



Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop angular error average


Glass Brain displaying tracts that had MD positively correlated with loop angular error average









Women

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.020210)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 1745 57.9862 11.0054 5516
Fornix_R 644 56.4255 8.47093 3180
Thalamic_Radiation_Superior_L 221 56.3348 7.35578 2394
Corpus_Callosum_Tapetum 179 57.229 8.15473 2989
Corpus_Callosum_Body 130 59.4769 7.46049 2600
Cingulum_Frontal_Parietal_L 115 59.1478 4.70187 1027
Uncinate_Fasciculus_R 62 57.2903 4.3642 857
Corpus_Callosum_Forceps_Major 44 57.5454 4.02718 733
Cerebellum_R 29 51.4483 3.74925 568
Thalamic_Radiation_Superior_R 17 52.4706 3.55904 522
Thalamic_Radiation_Anterior_L 15 58.5333 2.76317 351
Optic_Radiation_L 10 52 2.26758 210



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average


Glass Brain displaying tracts that had MD negatively correlated with loop angular error average









pre

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.065391)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 786 61.5242 8.65897 3623
Fornix_R 213 57.3052 5.41968 1322
Cerebellum_R 130 55.8461 5.92734 1541
Corpus_Callosum_Forceps_Major 61 60.3934 5.0109 1191
Optic_Radiation_L 41 55.6097 4.01767 705
Thalamic_Radiation_Superior_L 30 54.2 3.27294 456
Corpus_Callosum_Tapetum 29 56.2759 4.40336 857
Cingulum_Frontal_Parietal_L 10 54.4 1.6689 119
Inferior_Fronto_Occipital_Fasciculus_L 10 58.2 2.68689 330



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average


Glass Brain displaying tracts that had MD negatively correlated with loop angular error average









peri

Positive Correlations (FDR =1.000000)

Not significant



Negative Correlations (FDR = 0.004145)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Tapetum 129 61.2093 8.94091 3843
Corpus_Callosum_Forceps_Major 119 61.563 10.0329 4867
Cerebellum_R 89 54.5843 8.37367 3006
Corpus_Callosum_Body 81 63.5556 7.97912 3178
Corticostriatal_Tract_Posterior_R 69 55.6522 7.37753 2379
Fornix_L 64 63.8438 6.07902 1853
Inferior_Longitudinal_Fasciculus_R 63 63.8095 7.46397 2792
Cerebellum_L 54 53.1481 6.38356 1701
Corpus_Callosum_Forceps_Minor 38 58.6316 6.34176 1852
Arcuate_Fasciculus_R 28 58.6429 5.04227 1171
Inferior_Fronto_Occipital_Fasciculus_R 28 59.2143 4.90082 1117
Arcuate_Fasciculus_L 26 55.4615 4.48191 875
Inferior_Fronto_Occipital_Fasciculus_L 26 60.0769 5.17986 1266
Dentatorubrothalamic_Tract_L 19 57.0526 4.44164 884
Inferior_Longitudinal_Fasciculus_L 17 59.1765 4.1824 813
Fornix_R 17 59.6471 3.1607 468
Middle_Cerebellar_Peduncle 16 63.125 3.71435 684
Dentatorubrothalamic_Tract_R 13 59.3846 3.55667 590
Anterior_Commissure 13 57.2308 3.85504 668
Thalamic_Radiation_Superior_L 12 57.1667 3.52534 558
Superior_Longitudinal_Fasciculus2_L 11 58.5454 3.41103 535
Corticospinal_Tract_L 11 53.2727 3.2539 443
Optic_Radiation_L 11 55.4545 3.61445 569
Superior_Longitudinal_Fasciculus2_R 10 56 3.57143 561
Corticostriatal_Tract_Posterior_L 10 56.4 3.30892 485



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average


Glass Brain displaying tracts that had MD negatively correlated with loop angular error average









post

Positive Correlations (FDR = 1.000000)

Not significant



Negative Correlations (FDR = 0.028462)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Cerebellum_R 145 55.4897 11.2747 5540
Fornix_L 96 58.3125 6.09792 1703
Corpus_Callosum_Tapetum 69 60.058 7.13899 2404
Corpus_Callosum_Forceps_Major 59 65.0508 7.2696 2700
Cerebellum_L 50 55.76 6.51704 1860
Arcuate_Fasciculus_L 38 54.3158 5.38489 1237
Corticostriatal_Tract_Posterior_R 38 60.3684 5.77635 1582
Superior_Longitudinal_Fasciculus2_R 31 59.871 5.84595 1607
Corpus_Callosum_Body 31 55.0323 6.28991 1710
Inferior_Longitudinal_Fasciculus_R 26 60.7692 5.54028 1465
Arcuate_Fasciculus_R 24 58 4.89837 1093
Middle_Cerebellar_Peduncle 23 59.5652 5.24503 1287
Fornix_R 22 58.8182 3.06156 433
Inferior_Fronto_Occipital_Fasciculus_R 20 55.4 4.33588 818
Thalamic_Radiation_Superior_L 16 57 3.57763 573
Inferior_Longitudinal_Fasciculus_L 13 54.1538 3.88818 643
Corticopontine_Tract_Parietal_R 13 58.6154 3.84329 680
Corpus_Callosum_Forceps_Minor 12 53.6667 3.73818 589
Corticospinal_Tract_R 11 61.4545 3.33864 538



Figures

Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average


Glass Brain displaying tracts that had MD negatively correlated with loop angular error average









Peri and Post

Positive Correlations (FDR = 0.168126)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Inferior_Longitudinal_Fasciculus_L 156 56.8205 7.68993 2639
Cerebellum_R 149 53.3691 8.28908 2880
Cerebellum_L 125 52.992 7.20739 2162
Corpus_Callosum_Tapetum 61 56.1967 6.85329 2073
Arcuate_Fasciculus_L 49 61.7959 4.7216 1082
Arcuate_Fasciculus_R 39 56.4615 3.95602 694
Fornix_L 37 56.8108 4.21842 794
Fornix_R 35 53.3143 4.51873 855
Inferior_Longitudinal_Fasciculus_R 21 55.7143 3.72141 606
Corpus_Callosum_Forceps_Major 21 54.5714 4.05859 706
Middle_Cerebellar_Peduncle 21 52.8571 3.39681 479

Negative Correlations (FDR = 0.150048)
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Tapetum 409 58.2836 9.84303 4435
Fornix_L 392 55.7041 8.13459 2895
Cerebellum_R 176 55.125 7.46706 2414
Thalamic_Radiation_Superior_L 72 58.0556 4.92728 1107
Corpus_Callosum_Body 48 62.7917 5.15788 1312
Corpus_Callosum_Forceps_Major 29 54.3448 4.07567 709
Optic_Radiation_L 28 54.7143 3.70536 590
Inferior_Fronto_Occipital_Fasciculus_L 16 55.125 3.06227 406
Fornix_R 16 51 3.58918 516



Figures

Slice overlay image displaying ROIs with tracts that had MD positively correlated with loop angular error average


Slice overlay image displaying ROIs with tracts that had MD negatively correlated with loop angular error average


Glass Brain displaying tracts that had MD positively and negatively correlated with loop angular error average









Plots

## [1] "Fornix_L"
## [1] "Fornix_R"
## [1] "Thalamic_Radiation_Superior_L"
## [1] "Corpus_Callosum_Forceps_Major"
## [1] "Thalamic_Radiation_Superior_R"

AD

All subjects

Positive Correlations (FDR =0.414365)

Not significant

Negative Correlations (FDR =0.170648)

V1 V2 V3 V4
Tract Name Fornix_R Fornix_L NA
number of tracts 258 55 NA
mean length(mm) 56.2403 54.5455 NA
span(mm) 24.8933 23.2416 NA
curl 2.25925 2.34689 NA
elongation 10.7766 13.2591 NA
diameter(mm) 5.21872 4.11382 NA
volume(mm^3) 1203 725 NA
trunk volume(mm^3) 934 487 NA
branch volume(mm^3) 269 238 NA
total surface area(mm^2) 3746 3005 NA
total radius of end regions(mm) 8.96946 9.49018 NA
total area of end regions(mm^2) 260 85 NA
irregularity 4.06262 4.26276 NA
area of end region 1(mm^2) 134 45 NA
radius of end region 1(mm) 4.19124 5.24361 NA
irregularity of end region 1 0.411841 1.91955 NA
area of end region 2(mm^2) 126 40 NA
radius of end region 2(mm) 4.77822 4.24657 NA
irregularity of end region 2 0.569261 1.41634 NA
qa 0.139811 0.156539 NA
nqa 0.214807 0.240508 NA
gfa 0.085904 0.0920635 NA
iso 0.34444 0.365729 NA
dec_t 0.847703 0.843335 NA
inc_t 0.0329109 0.0290024 NA
ICBM152_adult.T1W 140.576 157.367 NA
ICBM152_adult.WM 33.0179 57.965 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.7214 1.51774 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 2.26025 2.28643 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.8732 1.81636 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.63839 1.56076 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 2.01496 2.04605 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 2.06103 1.90457 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 2.1793 2.26002 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.7135 1.64242 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.6594 1.54425 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 2.05707 1.65941 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.59434 1.45628 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 2.13418 1.73201 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 2.16287 1.74275 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 2.30758 2.12842 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.69603 1.62997 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 2.12856 1.7858 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.59043 1.43764 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 2.07493 1.81346 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.92869 1.81667 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 2.21783 2.23197 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.97472 1.88948 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 2.07906 1.84259 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 2.25307 2.03704 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.74078 1.45489 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 2.00664 1.77758 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 2.29225 2.07755 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 2.06865 1.42248 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 2.21017 1.79536 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.63538 1.49155 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.97618 1.85006 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.83374 1.70758 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 2.09145 1.75342 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 2.02717 1.85385 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.68992 1.55069 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 2.06634 1.52114 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.98374 1.6918 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 2.23675 2.22661 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 2.05145 1.73841 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 2.30366 2.13696 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.9987 1.80867 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.83602 1.64627 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.53399 1.43204 NA



Figures









Men

Positive Correlations (FDR =0.0033520)
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11
Tract Name Fornix_L Fornix_R Thalamic_Radiation_Superior_L Corpus_Callosum_Forceps_Major Cerebellum_L Cingulum_Frontal_Parietal_L Thalamic_Radiation_Posterior_L Thalamic_Radiation_Anterior_L Thalamic_Radiation_Superior_R NA
number of tracts 2073 519 472 182 104 85 50 25 11 NA
mean length(mm) 56.6097 55.0096 55.8263 55.4506 52.1538 59.6706 54 52.32 54.3636 NA
span(mm) 20.5789 21.6361 18.5888 22.4224 23.7273 25.8152 15.8776 25.1333 17.983 NA
curl 2.75086 2.54249 3.00322 2.473 2.19805 2.31146 3.40102 2.0817 3.02306 NA
elongation 5.09489 6.0746 6.32198 9.24715 9.76682 11.724 10.8476 15.4374 16.6901 NA
diameter(mm) 11.1111 9.05568 8.8305 5.9965 5.3399 5.08961 4.97805 3.38916 3.25724 NA
volume(mm^3) 5489 3543 3419 1566 1168 1214 1051 472 453 NA
trunk volume(mm^3) 4324 3247 2809 1275 1121 550 385 378 62 NA
branch volume(mm^3) 1165 296 610 291 47 664 666 94 391 NA
total surface area(mm^2) 11064 8426 9115 4123 3107 4000 3786 1861 2399 NA
total radius of end regions(mm) 14.4665 9.91991 11.1753 7.93851 5.96403 8.75045 6.55391 4.30815 5.94479 NA
total area of end regions(mm^2) 1356 561 529 184 148 118 85 42 21 NA
irregularity 5.59906 5.38408 5.88549 3.94693 3.55117 4.19243 4.48309 3.34069 4.31243 NA
area of end region 1(mm^2) 806 302 279 74 72 62 47 21 10 NA
radius of end region 1(mm) 8.36351 4.89025 5.79795 3.42923 3.12727 3.56612 3.68417 2.19183 2.50496 NA
irregularity of end region 1 0.272641 0.248774 0.378525 0.499242 0.426725 0.644393 0.907258 0.718697 1.9713 NA
area of end region 2(mm^2) 550 259 250 110 76 56 38 21 11 NA
radius of end region 2(mm) 6.10296 5.02966 5.37734 4.50928 2.83676 5.18433 2.86975 2.11632 3.43983 NA
irregularity of end region 2 0.212749 0.306851 0.363366 0.580728 0.332646 1.50781 0.680853 0.670028 3.37933 NA
qa 0.144672 0.120799 0.166695 0.215384 0.114369 0.13334 0.178445 0.112089 0.154195 NA
nqa 0.222275 0.185597 0.256112 0.330918 0.175718 0.204866 0.274166 0.172214 0.236907 NA
gfa 0.0792916 0.0704748 0.0840559 0.0934985 0.0375195 0.064991 0.0874217 0.0577302 0.0803539 NA
iso 0.3962 0.380806 0.421602 0.491852 0.725243 0.447415 0.431999 0.438454 0.409048 NA
dec_t 0.0672563 0.182092 0.0524579 0.0874555 0.0376331 0.0765191 0.0416243 0.0515352 0.106437 NA
inc_t 0.838802 0.442538 0.925306 0.780237 1.40182 0.705452 1.13458 0.672231 0.705644 NA
ICBM152_adult.T1W 179.475 173.52 192.959 177.989 174.272 193.728 195.48 190.347 198.551 NA
ICBM152_adult.WM 72.173 56.2382 127.043 132.374 23.8481 113.366 132.008 102.374 130.546 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.0712 1.11587 1.01477 1.4158 1.03776 0.99167 1.08675 0.980559 0.993983 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 1.9336 1.80969 1.8546 2.01597 1.10431 2.06104 1.91674 2.20515 1.72282 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.22609 1.17807 1.09441 1.38529 0.941077 1.06587 1.1187 1.07307 1.00378 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.1111 1.09781 0.997237 1.27556 0.785999 0.986329 0.996197 0.978182 1.00353 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 1.38824 1.24122 1.31034 1.33105 0.878736 1.26151 1.30568 1.25215 1.06906 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.2653 1.15895 1.15436 1.24721 0.930617 1.14352 1.19061 1.16091 1.00339 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 1.96103 1.77278 1.94926 1.48472 1.04893 1.7999 1.8441 1.7919 1.75869 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.15065 1.11851 1.07451 1.25746 0.906912 1.04424 1.10346 1.01771 1.01545 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.14067 1.05609 1.07656 1.25654 1.11494 1.06009 1.08454 1.02853 1.03755 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.15635 1.21594 1.11117 1.2295 0.916022 1.08478 1.14256 1.08045 1.09866 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.15427 1.05988 1.13879 1.23231 0.997248 1.03839 1.08043 1.05883 0.946578 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.24266 1.3377 1.29904 1.43572 0.943268 1.37382 1.31908 1.3787 1.22264 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 1.19663 1.39485 1.09866 1.41356 0.94359 1.05054 1.15175 1.05436 1.11062 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.49784 1.56477 1.45104 1.47191 1.1173 1.32117 1.46127 1.27584 1.32857 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.11509 1.12068 1.07173 1.38416 0.92033 1.08115 1.09199 1.04709 1.06156 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.24678 1.32863 1.22386 1.25103 1.18916 1.324 1.20442 1.37143 1.20742 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.12655 1.0908 1.02614 1.26115 0.920489 0.941721 1.06975 0.939893 0.985566 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.34676 1.3529 1.36883 1.37646 1.28866 1.22961 1.33272 1.2029 1.2235 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.26505 1.27963 1.27222 1.761 0.87272 1.43076 1.20998 1.47676 1.22711 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 1.75745 1.53116 1.65704 1.49922 0.986637 1.60668 1.57512 1.68088 1.31443 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.20894 1.11924 1.16449 1.40676 0.954399 1.15888 1.15266 1.19604 0.989729 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.24832 1.313 1.20863 1.47223 0.81432 1.24381 1.20218 1.23378 1.10969 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.62496 1.73921 1.58725 1.22093 1.09367 1.33721 1.54457 1.2736 1.59056 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.10687 1.10012 1.03284 1.30674 0.984001 1.07084 1.0365 1.08627 0.982241 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 1.19486 1.19914 1.14431 1.1994 0.965197 1.13141 1.16965 1.06496 1.05975 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.46706 1.54699 1.40485 1.37942 0.93584 1.40099 1.33852 1.41447 1.36523 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.1101 1.27718 1.07868 1.36436 0.87958 1.12649 1.076 1.07205 1.14483 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.47521 1.67159 1.42462 1.5882 0.880902 1.37531 1.45845 1.39322 1.45266 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.14375 1.06286 1.08207 1.39948 1.08424 1.03087 1.1293 1.04175 1.02459 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.32559 1.3025 1.16968 1.22227 0.828092 1.19534 1.14799 1.23013 1.13961 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.20129 1.16065 1.1493 1.33036 0.973418 1.14294 1.17788 1.11934 1.0767 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.22189 1.40968 1.14875 1.23401 0.873207 1.07693 1.16425 1.07859 1.10124 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 1.30709 1.27194 1.27928 1.39697 1.1221 1.17139 1.29027 1.15396 1.16149 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.13213 1.08287 1.11929 1.35145 0.920245 1.00474 1.13428 0.992351 1.02456 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 1.16512 1.3027 1.12331 1.34127 0.811239 0.996001 1.13527 0.991167 1.11134 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.20955 1.32233 1.16156 1.26385 1.04544 1.09894 1.19992 1.05921 1.20022 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 2.14792 2.09676 2.10406 2.14873 1.28413 2.13007 2.15585 2.2091 1.94801 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.15004 1.19128 1.06952 1.26946 1.05517 1.01754 1.0812 0.995945 1.0123 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 1.70987 1.72785 1.72003 1.59988 0.898706 1.85571 1.63014 1.99083 1.56691 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.33293 1.3348 1.23603 1.34482 1.01551 1.18955 1.21109 1.15367 1.18164 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.13373 1.14474 1.02571 1.38229 0.89964 1.03276 1.04326 1.01477 1.00265 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.15659 1.13487 1.17543 1.49471 1.07045 1.16982 1.22189 1.1566 1.12615 NA



Negative Correlations (FDR =1.000000)











Women

Positive Correlations (FDR = )
V1 V2 V3 V4
Tract Name Cerebellum_R Cerebellum_L NA
number of tracts 24 13 NA
mean length(mm) 52.0833 54 NA
span(mm) 24.7233 24.9969 NA
curl 2.10665 2.16026 NA
elongation 16.1966 17.1393 NA
diameter(mm) 3.2157 3.15064 NA
volume(mm^3) 423 421 NA
trunk volume(mm^3) 394 0 NA
branch volume(mm^3) 29 421 NA
total surface area(mm^2) 1691 2519 NA
total radius of end regions(mm) 2.91898 7.4443 NA
total area of end regions(mm^2) 30 19 NA
irregularity 3.2138 4.71287 NA
area of end region 1(mm^2) 17 10 NA
radius of end region 1(mm) 1.33241 3.1006 NA
irregularity of end region 1 0.328077 3.02023 NA
area of end region 2(mm^2) 13 9 NA
radius of end region 2(mm) 1.58657 4.34371 NA
irregularity of end region 2 0.608311 6.5861 NA
qa 0.116766 0.119597 NA
nqa 0.179401 0.18375 NA
gfa 0.039757 0.0399798 NA
iso 0.647932 0.700178 NA
dec_t 0.252948 0.129667 NA
inc_t 0.395081 0.723857 NA
ICBM152_adult.T1W 158.892 141.756 NA
ICBM152_adult.WM 20.3144 8.28096 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.25451 1.23074 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 1.29586 0.997941 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 0.899762 0.985351 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.08338 0.93451 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 0.876574 1.04776 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.26307 1.11976 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 1.51827 1.26383 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.20549 1.38281 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.1081 1.1229 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.00941 0.907047 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 0.948671 1.13049 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.24006 1.07067 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 0.987838 1.04837 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.48736 1.10719 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.06595 1.00104 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.56057 1.51112 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.67971 1.15646 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.25305 1.43074 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 0.958568 0.978476 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 1.02607 1.13138 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.22179 1.01962 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.1504 0.948938 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.23749 1.0504 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.24654 0.927987 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 0.967482 0.951621 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.13363 1.24969 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.14385 1.04686 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 0.893614 1.06038 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 0.932182 1.14689 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.05343 1.03698 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.07078 0.989572 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.18365 1.11873 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 0.976655 1.1852 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.05363 0.968174 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 0.902692 0.936381 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.26277 1.1246 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 0.887391 1.12344 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 0.913302 1.11096 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 0.881927 1.03906 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.60521 1.1763 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.00536 1.04093 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.2685 1.35052 NA



Negative Correlations (FDR = )
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10
Tract Name Fornix_L Fornix_R Thalamic_Radiation_Superior_L Cingulum_Frontal_Parietal_L Optic_Radiation_L Cerebellum_R Inferior_Fronto_Occipital_Fasciculus_L Thalamic_Radiation_Anterior_L NA
number of tracts 853 182 167 87 27 18 14 12 NA
mean length(mm) 55.6764 54.1758 55.3054 58.8966 55.7778 51.5555 53.7143 56.5 NA
span(mm) 22.8501 24.0784 17.9861 25.6409 26.963 24.8634 25.9586 25.4463 NA
curl 2.4366 2.24998 3.0749 2.29697 2.06868 2.07355 2.06923 2.22036 NA
elongation 6.38781 9.12751 8.05633 12.7246 17.4616 17.4364 17.1674 20.6561 NA
diameter(mm) 8.71604 5.93544 6.86484 4.62857 3.19432 2.95678 3.12885 2.73527 NA
volume(mm^3) 3322 1499 2047 991 447 354 413 332 NA
trunk volume(mm^3) 2713 1176 860 543 266 354 157 105 NA
branch volume(mm^3) 609 323 1187 448 181 0 256 227 NA
total surface area(mm^2) 8766 5231 6944 3976 1898 1578 2284 1844 NA
total radius of end regions(mm) 12.5643 8.70641 15.4934 7.91916 4.69117 3.26864 6.86511 6.3616 NA
total area of end regions(mm^2) 779 208 226 123 36 29 25 23 NA
irregularity 5.74991 5.17817 5.82186 4.64258 3.39084 3.29506 4.32585 3.79807 NA
area of end region 1(mm^2) 389 90 133 60 16 15 12 11 NA
radius of end region 1(mm) 6.38153 4.06642 7.43752 3.01922 1.7234 1.71272 3.12105 2.55992 NA
irregularity of end region 1 0.32889 0.577208 1.30664 0.477295 0.583179 0.614375 2.55018 1.87159 NA
area of end region 2(mm^2) 390 118 93 63 20 14 13 12 NA
radius of end region 2(mm) 6.1828 4.63999 8.05591 4.89994 2.96777 1.55592 3.74406 3.80168 NA
irregularity of end region 2 0.307933 0.573194 2.19228 1.19727 1.3835 0.543244 3.3876 3.78372 NA
qa 0.152304 0.143521 0.158462 0.118654 0.253276 0.114273 0.241524 0.107836 NA
nqa 0.234002 0.220507 0.243462 0.182301 0.389137 0.175571 0.37108 0.16568 NA
gfa 0.0874158 0.0848453 0.0791854 0.0587555 0.110141 0.0376683 0.106485 0.0544182 NA
iso 0.378304 0.359332 0.422244 0.446795 0.485475 0.715224 0.483482 0.449001 NA
dec_t 1.10219 0.71461 0.838796 0.785418 0.910068 0.768815 0.821057 0.616299 NA
inc_t 0.0464779 0.117264 0.0356806 0.0421295 0.0914356 0.0587694 0.0844156 0.077825 NA
ICBM152_adult.T1W 165.102 158.789 179.705 193.593 199.766 186.553 196.554 192.994 NA
ICBM152_adult.WM 60.156 54.7371 104.001 104.853 183.048 79.5257 174.687 96.041 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.41881 1.54669 1.0519 1.06524 1.41629 1.3216 1.42571 1.04344 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 2.25489 2.25112 2.0466 2.18747 1.81303 0.83578 1.87789 2.20866 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.66244 1.65128 1.27207 1.10058 1.31064 1.15028 1.28375 1.06255 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.41327 1.38616 1.04495 1.04064 1.23332 0.900686 1.22072 1.019 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 1.87325 1.76385 1.49552 1.37079 1.16416 1.0088 1.19289 1.27933 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.71271 1.77436 1.32769 1.23022 1.16087 0.811346 1.16449 1.16137 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 2.16422 2.11565 1.99299 1.93242 1.45836 0.864423 1.43868 1.9437 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.50996 1.48228 1.16831 1.09278 1.18455 0.832566 1.22698 1.10573 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.44085 1.50271 1.12186 1.14762 1.31184 0.906587 1.2844 1.15726 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.49891 1.8013 1.24504 1.08155 1.2295 0.848103 1.28943 1.00945 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.34478 1.37107 1.25972 1.0309 1.20482 0.749862 1.221 0.982992 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.62094 1.95448 1.49171 1.5217 1.35614 0.900831 1.36038 1.46189 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 1.59783 1.9796 1.17117 1.11123 1.41278 0.855255 1.36649 1.11934 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.96869 2.19325 1.64318 1.32164 1.37393 0.904326 1.34418 1.21134 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.51943 1.61421 1.1974 1.10369 1.44413 1.07171 1.41171 1.05584 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.64273 1.93858 1.39032 1.49901 1.23009 1.05317 1.22874 1.47887 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.34692 1.39236 1.0118 0.96342 1.15274 0.963098 1.19583 0.956028 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.669 1.84946 1.52768 1.29321 1.3533 0.989774 1.33871 1.23221 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.66522 1.67163 1.55221 1.59083 1.62342 0.78324 1.69349 1.52366 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 2.12436 2.04973 1.77824 1.77796 1.3751 0.959782 1.44269 1.7392 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.69502 1.67043 1.31072 1.31881 1.29245 0.965573 1.35028 1.27893 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.68088 1.86957 1.38587 1.31823 1.44703 0.951918 1.45118 1.30433 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.88295 2.10441 1.67603 1.40385 1.32214 0.992855 1.30867 1.35858 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.36234 1.55742 1.07986 1.08725 1.33654 0.856834 1.31238 1.10758 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 1.61058 1.7916 1.29589 1.2869 1.25668 0.799752 1.27172 1.20954 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.93823 2.11468 1.64001 1.47811 1.41107 0.889697 1.40948 1.42423 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.32026 1.74914 1.15414 1.18326 1.25333 0.863577 1.2964 1.15822 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.73717 2.1945 1.58595 1.57788 1.56416 0.918219 1.54895 1.50235 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.39504 1.51157 1.13989 1.12269 1.37667 1.03544 1.40463 1.14059 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.69097 1.73239 1.35056 1.31767 1.09679 0.939652 1.14876 1.27193 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.62558 1.66467 1.20047 1.16154 1.37298 0.90494 1.41278 1.19152 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.61426 1.99932 1.24924 1.0895 1.16919 0.824072 1.19023 1.07718 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 1.6901 1.75983 1.47876 1.13521 1.42138 1.02985 1.3973 1.04916 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.43406 1.54023 1.21325 1.02393 1.28915 1.00348 1.25021 0.971326 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 1.39857 1.73917 1.18266 0.977441 1.25133 0.786046 1.23068 0.931464 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.56232 1.80578 1.28071 1.067 1.22398 0.834402 1.20722 1.0198 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 2.22498 2.23726 2.08651 2.19615 1.80971 1.05205 1.77903 2.25157 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.57281 1.80577 1.15391 1.10941 1.16732 1.10875 1.14971 1.08692 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 2.01307 2.16241 1.913 2.01167 1.55932 1.0184 1.61414 2.01093 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.67958 1.82064 1.40386 1.28058 1.36764 1.12757 1.37761 1.21209 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.52283 1.58348 1.10584 1.05983 1.4148 0.963236 1.43633 1.05649 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.36632 1.4592 1.23164 1.24061 1.46875 0.955463 1.44463 1.23525 NA



Figures









pre

Positive Correlations (FDR = )



Negative Correlations (FDR = )
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11 V12 V13
Tract Name Fornix_L Cerebellum_R Fornix_R Corpus_Callosum_Forceps_Major Thalamic_Radiation_Superior_L Corpus_Callosum_Tapetum Optic_Radiation_L Thalamic_Radiation_Superior_R Corticospinal_Tract_L Cingulum_Frontal_Parietal_L Optic_Radiation_R NA
number of tracts 880 323 272 85 70 43 40 22 18 15 10 NA
mean length(mm) 59.1159 56.6502 57.9265 59.4588 55.5143 55.814 54.55 55.6364 56.2222 58.2667 52.2 NA
span(mm) 22.9562 25.8342 23.983 24.9055 17.9653 19.5002 26.1914 16.4482 27.4981 25.5424 21.0456 NA
curl 2.57516 2.19284 2.41532 2.38738 3.09008 2.86223 2.08274 3.38251 2.04458 2.28117 2.48032 NA
elongation 6.099 6.10906 8.39714 8.9873 10.5951 11.6451 12.8176 18.2524 18.7034 17.1213 22.2329 NA
diameter(mm) 9.69272 9.27314 6.89835 6.61588 5.23962 4.7929 4.25587 3.04817 3.00599 3.40316 2.34787 NA
volume(mm^3) 4362 3826 2165 2044 1197 1007 776 406 399 530 226 NA
trunk volume(mm^3) 2789 1980 1556 112 291 167 121 0 62 0 73 NA
branch volume(mm^3) 1573 1846 609 1932 906 840 655 406 337 530 153 NA
total surface area(mm^2) 12654 13208 7852 8809 5344 4179 4186 2446 1962 3522 1629 NA
total radius of end regions(mm) 16.3062 12.3786 12.4515 16.7307 15.3917 15.1211 13.2143 8.99344 7.76873 15.2854 7.81095 NA
total area of end regions(mm^2) 811 389 297 127 90 67 58 29 30 24 16 NA
irregularity 7.02956 8.00312 6.25472 7.12809 5.84806 4.97257 5.73939 4.59102 3.69533 5.65375 4.23084 NA
area of end region 1(mm^2) 374 203 124 60 47 36 29 14 16 12 8 NA
radius of end region 1(mm) 8.39552 5.63489 6.68495 8.96237 8.26499 8.73049 6.32685 4.55723 4.37691 7.27417 2.65763 NA
irregularity of end region 1 0.59207 0.491388 1.1322 4.20576 4.56601 6.65158 4.33637 4.6604 3.76154 13.8527 2.77363 NA
area of end region 2(mm^2) 437 186 173 67 43 31 29 15 14 12 8 NA
radius of end region 2(mm) 7.9107 6.74372 5.7665 7.76835 7.12675 6.3906 6.88748 4.43621 3.39181 8.01124 5.15332 NA
irregularity of end region 2 0.449882 0.768132 0.60385 2.82965 3.71078 4.13877 5.13893 4.12176 2.58158 16.8023 10.4288 NA
qa 0.156792 0.11764 0.149235 0.298184 0.169174 0.303226 0.244959 0.153841 0.294133 0.182193 0.167073 NA
nqa 0.240897 0.180744 0.229287 0.458133 0.259921 0.465879 0.376357 0.236363 0.451909 0.279924 0.256693 NA
gfa 0.087523 0.0388161 0.085935 0.121951 0.0822952 0.13406 0.098861 0.0798277 0.114833 0.0884387 0.0857949 NA
iso 0.382918 0.691591 0.365947 0.504218 0.433598 0.445191 0.551109 0.405388 0.544837 0.443201 0.41045 NA
dec_t 1.26302 0.758592 1.53229 0.833089 1.02547 0.506595 0.883773 1.04395 1.72815 1.00033 1.04634 NA
inc_t 0.0620926 0.167474 0.0777732 0.239787 0.0749169 0.249669 0.120734 0.0987231 0.0228521 0.11436 0.171514 NA
ICBM152_adult.T1W 165.398 170.713 164.503 187.786 190.832 199.034 194.455 193.029 213.758 203.322 158.796 NA
ICBM152_adult.WM 53.9414 35.6033 54.3804 158.174 124.708 193.114 159.046 121.491 239.445 171.666 91.5252 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.37702 1.1415 1.44248 1.67431 1.03654 1.58011 1.39631 1.04183 1.09576 1.0977 1.32021 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 2.15683 1.29272 2.11485 2.14086 1.94191 1.93855 1.89864 1.76691 1.12716 1.73494 1.95965 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.58376 0.914994 1.54363 1.56262 1.14592 1.58156 1.30923 1.03657 1.07534 1.09405 1.40329 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.39357 0.904493 1.36506 1.4033 1.03708 1.35782 1.18729 1.03484 1.07304 1.0687 1.14561 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 1.71213 0.914914 1.65419 1.68009 1.3478 1.49212 1.19304 1.13941 1.06492 1.22878 1.35038 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.58334 1.09618 1.61945 1.53728 1.22284 1.46322 1.2428 1.0517 1.08072 1.17188 1.24534 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 2.03089 1.22488 2.01651 1.83061 1.91533 1.74624 1.65936 1.69988 1.10521 1.53681 1.65265 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.46008 1.16795 1.4421 1.61818 1.09595 1.44252 1.22333 1.02604 1.06001 1.0923 1.28205 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.41664 0.981396 1.39763 1.39536 1.10342 1.35282 1.30066 1.03341 1.07674 1.12124 1.42745 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.42114 0.909526 1.65144 1.60598 1.15366 1.49083 1.27728 1.10911 1.12212 1.11264 1.30054 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.33915 0.89083 1.3699 1.45891 1.1671 1.50116 1.18952 0.98835 1.02309 1.05617 1.16668 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.53483 1.08787 1.77844 1.5674 1.37797 1.63604 1.29123 1.24507 1.14927 1.33695 1.62341 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 1.52694 1.01523 1.8404 1.53289 1.12048 1.58268 1.31966 1.15104 1.10407 1.10282 1.52662 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.79843 1.10667 1.98398 1.53608 1.46676 1.48667 1.26187 1.37741 1.12538 1.22048 1.65738 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.44437 0.944532 1.46809 1.6563 1.11893 1.41997 1.43952 1.06581 1.09688 1.13918 1.44458 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.58183 1.17978 1.79023 1.38739 1.31364 1.34681 1.16322 1.25604 1.09509 1.29628 1.57743 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.34103 1.20154 1.36227 1.53825 1.01894 1.47989 1.24768 1.01114 0.983256 1.03518 1.30955 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.60005 1.04151 1.74024 1.47959 1.38714 1.48302 1.25677 1.29 1.12132 1.17303 1.52718 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.58464 0.846609 1.63139 1.92941 1.40384 1.61005 1.68569 1.30956 1.04628 1.32012 1.43595 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 2.01523 0.9385 1.93344 1.85733 1.66163 1.72266 1.47624 1.35616 1.13691 1.45568 1.54448 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.57538 0.992694 1.55411 1.49806 1.22764 1.5598 1.21512 1.04785 1.12564 1.12311 1.31394 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.60265 1.00799 1.73097 1.56314 1.27425 1.55193 1.35785 1.19272 1.09122 1.20672 1.5707 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.81212 1.09821 2.0266 1.48242 1.55157 1.42512 1.29311 1.57385 1.12294 1.23833 1.38064 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.3364 1.10781 1.45216 1.44223 1.07556 1.36424 1.27579 1.01336 1.05367 1.11168 1.36288 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 1.54068 0.942766 1.6497 1.40431 1.22329 1.45088 1.18757 1.1048 1.10647 1.22364 1.36098 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.81985 1.08125 1.97435 1.47077 1.47837 1.4184 1.26146 1.41116 1.11816 1.33272 1.6868 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.30769 1.05174 1.66604 1.61449 1.12751 1.49244 1.27554 1.2554 1.06629 1.12608 1.29423 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.66813 0.914825 2.04549 1.75293 1.43805 1.59781 1.55062 1.47343 1.09099 1.30391 1.83675 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.37031 0.89951 1.39375 1.56633 1.11225 1.62023 1.28902 1.073 1.0976 1.04737 1.42848 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.63497 0.941146 1.66021 1.58731 1.23157 1.46848 1.21859 1.19202 1.12747 1.14569 1.43926 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.52272 1.0445 1.52648 1.55004 1.19805 1.51553 1.47172 1.10613 1.04768 1.14315 1.47779 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.5467 1.04677 1.83533 1.41105 1.16525 1.36589 1.1376 1.13877 1.05745 1.09815 1.50097 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 1.59545 0.933343 1.67937 1.5858 1.30868 1.50919 1.42878 1.19175 1.11162 1.12336 1.35133 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.40459 0.90798 1.41642 1.58576 1.1288 1.51988 1.35343 1.07657 1.08257 1.11136 1.45937 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 1.38188 0.866233 1.67229 1.39235 1.12417 1.40123 1.1615 1.21463 1.07743 1.04923 1.30455 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.47343 1.17195 1.65397 1.53662 1.17404 1.441 1.25543 1.22469 1.07913 1.08153 1.38803 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 2.16424 1.09287 2.18453 1.98902 2.05062 1.74219 1.77651 1.96383 1.08145 1.70256 1.7569 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.48528 0.932166 1.62624 1.42393 1.09138 1.3918 1.1539 1.03252 1.04417 1.08424 1.36825 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 1.90398 0.85627 2.03083 1.85173 1.80333 1.79611 1.65653 1.61525 1.10567 1.56743 1.717 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.62924 1.23304 1.70498 1.53185 1.28432 1.4677 1.51514 1.24983 1.18025 1.17948 1.49086 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.42724 0.928633 1.51109 1.55593 1.1007 1.43534 1.44078 1.02705 1.06146 1.10115 1.16466 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.34713 1.05714 1.34653 1.64429 1.18464 1.46535 1.50943 1.10853 1.06046 1.16113 1.46365 NA



Figures









peri

Positive Correlations (FDR = )



Negative Correlations (FDR = )
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11 V12 V13 V14 V15 V16 V17 V18 V19 V20 V21 V22 V23 V24 V25 V26 V27 V28 V29 V30 V31 V32 V33
Tract Name Corpus_Callosum_Tapetum Cerebellum_R Corpus_Callosum_Forceps_Major Cerebellum_L Fornix_L Corpus_Callosum_Body Inferior_Longitudinal_Fasciculus_L Arcuate_Fasciculus_R Middle_Cerebellar_Peduncle Corticostriatal_Tract_Posterior_R Inferior_Fronto_Occipital_Fasciculus_R Dentatorubrothalamic_Tract_R Inferior_Longitudinal_Fasciculus_R Corticospinal_Tract_R Corticospinal_Tract_L Fornix_R Inferior_Fronto_Occipital_Fasciculus_L Optic_Radiation_L Corticopontine_Tract_Parietal_L Dentatorubrothalamic_Tract_L Arcuate_Fasciculus_L Corticostriatal_Tract_Posterior_L Cingulum_Parolfactory_R Thalamic_Radiation_Posterior_L Medial_Lemniscus_R Superior_Longitudinal_Fasciculus2_L Thalamic_Radiation_Posterior_R Thalamic_Radiation_Anterior_R Corpus_Callosum_Forceps_Minor Anterior_Commissure Corticopontine_Tract_Parietal_R NA
number of tracts 187 106 85 63 56 50 37 36 35 34 31 26 25 25 20 20 19 19 18 18 16 16 15 14 14 13 13 12 12 11 10 NA
mean length(mm) 67.861 54.2264 62.2824 53.9365 60.4643 59.24 56.0541 63.6111 54.6857 57.7059 56.6452 60.9231 59.2 61.84 58.9 69.2 59.6842 59.8947 61.1111 56.3333 59.5 55.5 62.8 57.4286 63.8571 55.5385 58.3077 52.8333 59.5 58.5454 56 NA
span(mm) 24.4121 24.7535 24.067 24.9687 21.0073 23.1856 26.8727 23.0028 23.0734 25.6827 25.5956 27.5462 26.0643 29.2957 27.955 23.7237 27.9619 28.6987 28.5194 25.5413 25.1393 24.9305 28.2417 25.2103 28.1538 22.5045 24.8551 25.2105 23.4634 26 26.0864 NA
curl 2.77981 2.19065 2.58787 2.16016 2.87825 2.55504 2.08591 2.76536 2.37008 2.24688 2.21308 2.21167 2.2713 2.11089 2.10696 2.91692 2.13449 2.08702 2.14279 2.20558 2.36681 2.22619 2.22366 2.27798 2.26816 2.46788 2.34591 2.09569 2.53586 2.25175 2.14672 NA
elongation 6.67057 6.13344 7.71859 8.06639 10.4298 8.65445 10.0964 12.4558 9.93995 9.15161 9.64665 10.9953 10.7579 14.1094 13.9898 20.293 13.1476 13.2723 17.6867 12.6892 13.6803 13.4791 17.286 13.5769 17.876 16.1321 14.5246 15.4538 16.7738 17.7719 17.7456 NA
diameter(mm) 10.1732 8.8411 8.06914 6.68657 5.79725 6.84504 5.5519 5.10694 5.50161 6.30554 5.872 5.54083 5.50295 4.3829 4.21022 3.41005 4.53956 4.51277 3.45519 4.43946 4.34933 4.11747 3.633 4.22988 3.57224 3.44273 4.0144 3.41879 3.5472 3.29427 3.15572 NA
volume(mm^3) 5516 3329 3185 1894 1596 2180 1357 1303 1300 1802 1534 1469 1408 933 820 632 966 958 573 872 884 739 651 807 640 517 738 485 588 499 438 NA
trunk volume(mm^3) 347 246 91 170 0 0 0 71 0 0 0 125 0 100 186 112 0 79 178 78 0 0 0 110 128 91 0 0 0 127 0 NA
branch volume(mm^3) 5169 3083 3094 1724 1596 2180 1357 1232 1300 1802 1534 1344 1408 833 634 520 966 879 395 794 884 739 651 697 512 426 738 485 588 372 438 NA
total surface area(mm^2) 26939 17247 18824 9260 8896 15288 8384 6883 8988 12199 11567 11481 10809 5361 4991 4017 6992 5373 3709 6763 6287 6925 3569 6742 5301 4676 6260 3697 5313 3975 3598 NA
total radius of end regions(mm) 37.6263 17.2533 30.8251 9.56177 16.9901 32.9691 22.3446 23.6205 29.6233 22.4203 39.0095 43.9042 25.4112 15.1263 17.9092 13.3041 23.1645 12.5831 11.8707 18.9554 27.5207 25.0369 16.7816 26.7503 28.205 41.8618 26.2008 15.3166 23.7876 53.9598 12.1716 NA
total area of end regions(mm^2) 276 164 142 97 79 80 60 54 59 61 56 48 43 39 35 30 32 35 26 33 30 27 25 26 24 22 26 23 21 18 16 NA
irregularity 12.4209 11.4511 11.9226 8.17287 8.07837 12.0008 8.57537 6.74426 9.50932 10.6717 11.0693 10.8261 10.5613 6.29601 6.40646 5.41858 8.21445 6.32754 5.59132 8.60783 7.73311 9.64598 4.97933 8.83452 7.39704 7.78444 8.51291 6.51508 8.01286 6.56048 6.48075 NA
area of end region 1(mm^2) 135 77 71 46 47 40 29 29 32 30 29 24 22 20 17 16 18 18 13 17 15 13 13 12 12 12 13 11 11 10 7 NA
radius of end region 1(mm) 20.6051 7.32356 18.2434 3.73484 9.71401 16.4623 12.54 11.2833 20.3052 12.1933 20.7729 21.566 12.3497 6.57471 8.72392 9.96857 12.1761 6.62504 5.54667 12.5034 14.693 14.8119 8.65828 15.5392 12.9402 22.1432 15.1756 7.4519 11.4081 35.0328 8.38828 NA
irregularity of end region 1 9.88017 2.18828 14.7267 0.952656 6.30738 21.2849 17.0352 13.7919 40.4775 15.5694 46.7462 60.8806 21.7791 6.79006 14.0645 19.5117 25.8759 7.66045 7.43483 28.8908 45.2145 53.0186 18.1163 63.2161 43.8383 128.366 55.6539 15.8596 37.1695 385.568 31.5789 NA
area of end region 2(mm^2) 141 87 71 51 32 40 31 25 27 31 27 24 21 19 18 14 14 17 13 16 15 14 12 14 12 10 13 12 10 8 9 NA
radius of end region 2(mm) 17.0212 9.92971 12.5816 5.82693 7.27613 16.5068 9.80459 12.3372 9.31811 10.227 18.2365 22.3382 13.0615 8.55155 9.18528 3.33548 10.9884 5.95807 6.32401 6.45196 12.8277 10.225 8.12331 11.211 15.2648 19.7186 11.0252 7.86474 12.3794 18.9269 3.78333 NA
irregularity of end region 2 6.45523 3.56044 7.00431 2.09151 5.19757 21.4 9.74198 19.1268 10.1028 10.5996 38.6965 65.3182 25.5222 12.0917 14.7252 2.49654 27.095 6.56012 9.66478 8.17361 34.4633 23.4609 17.2756 28.2042 61.0027 122.153 29.3753 16.1934 48.1452 140.676 4.99639 NA
qa 0.296335 0.116333 0.332111 0.128864 0.159208 0.302124 0.198843 0.231803 0.209688 0.232012 0.221228 0.223915 0.206027 0.324875 0.325706 0.156229 0.260891 0.262275 0.332753 0.246155 0.230266 0.244525 0.199925 0.223027 0.247221 0.17261 0.226096 0.185142 0.220137 0.203702 0.253108 NA
nqa 0.455292 0.178736 0.510259 0.197989 0.244608 0.464187 0.305505 0.356145 0.322168 0.356466 0.339897 0.344025 0.316542 0.499142 0.500418 0.240032 0.400837 0.402963 0.511245 0.378195 0.353784 0.37569 0.307166 0.342661 0.379833 0.2652 0.347376 0.284455 0.338221 0.31297 0.388878 NA
gfa 0.133444 0.0385955 0.125443 0.0406948 0.0852446 0.129885 0.0968044 0.0981702 0.100797 0.0999906 0.0953607 0.102842 0.0950194 0.133906 0.132048 0.0908847 0.111152 0.102839 0.137535 0.104894 0.0936754 0.0996459 0.0975969 0.0943334 0.109391 0.0697864 0.0973669 0.0951471 0.101939 0.0959423 0.111485 NA
iso 0.432528 0.697311 0.555635 0.728421 0.392475 0.458745 0.437904 0.494151 0.428851 0.509561 0.514027 0.450712 0.484971 0.488886 0.495111 0.363554 0.501448 0.567808 0.469119 0.489199 0.517807 0.535767 0.455605 0.502289 0.46089 0.555392 0.500899 0.406552 0.455444 0.447966 0.467195 NA
dec_t 0.804814 1.21379 0.710693 0.921837 0.409006 0.728625 0.718269 0.787538 0.763529 0.809421 0.798364 0.595799 0.681646 0.755737 0.572204 0.219595 0.602151 0.395602 0.632019 0.613206 0.886251 0.783096 0.343802 0.576972 0.801194 0.884456 0.764758 0.5417 0.513455 0.680115 0.801881 NA
inc_t 0.171838 0.166446 0.203903 0.184256 0.219588 0.218673 0.243072 0.186984 0.253006 0.18051 0.209723 0.355148 0.215144 0.376846 0.353431 0.505657 0.2931 0.283665 0.230292 0.364379 0.149721 0.261111 0.366175 0.379447 0.318247 0.171168 0.29503 0.360186 0.278571 0.221153 0.232352 NA
ICBM152_adult.T1W 204.278 175.311 194.024 159.358 173.973 202.433 220.234 225.731 212.446 221.206 211.956 207.204 219.897 208.377 210.297 166.275 210.355 205.124 214.677 208.39 223.435 218.321 196.868 214.731 209.854 221.717 220.704 204.724 213.302 198.724 221.772 NA
ICBM152_adult.WM 199.831 48.7468 178.547 18.5828 69.1919 200.206 222.941 250.816 219.817 240.01 206.961 204.718 233.921 233.368 238.81 74.3437 209.995 185.251 242.969 217.343 251.156 233.189 155.136 219.447 218.278 246.713 232.804 176.344 217.958 150.055 250.635 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.44243 1.18435 1.53373 1.11596 1.1861 1.44093 1.2229 1.07948 1.34464 1.16156 1.17575 1.10393 1.15756 1.14659 1.11576 1.46619 1.39683 1.40581 1.19294 1.03095 1.11648 1.25494 1.13532 1.18082 1.13444 1.07862 1.13139 1.02888 1.4192 1.33552 1.11155 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 1.60475 0.939793 1.61043 0.97182 1.98279 1.55858 1.27918 1.11097 1.26358 1.10267 1.15796 1.13671 1.14597 1.2064 1.18407 1.93921 1.61608 1.79113 1.24727 1.12793 1.08009 1.30328 1.05725 1.23046 1.18573 1.07736 1.10503 1.12839 1.54723 1.57621 1.13615 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.43625 1.02869 1.40806 1.00834 1.32742 1.36194 1.17356 1.11591 1.32803 1.11747 1.16086 1.09643 1.12788 1.1356 1.091 1.56 1.28384 1.29586 1.16285 1.00936 1.06092 1.16457 1.07459 1.07055 1.12503 1.07062 1.08923 1.03956 1.35359 1.27955 1.08401 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.31156 0.914442 1.41628 0.851291 1.21955 1.40587 1.14369 1.11021 1.30749 1.12147 1.15437 1.14211 1.12368 1.18156 1.14273 1.39564 1.22725 1.20135 1.19506 1.03485 1.05687 1.16447 1.15145 1.08927 1.14468 1.02806 1.10091 1.05312 1.34825 1.2374 1.06748 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 1.39433 1.01296 1.55394 0.975557 1.49701 1.36025 1.10474 1.09713 1.23857 1.13982 1.15997 1.09414 1.10595 1.11232 1.1059 1.69107 1.27308 1.23931 1.19682 1.04887 1.05743 1.17918 1.10312 1.10912 1.11823 1.03237 1.10812 1.06415 1.26019 1.20128 1.07238 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.35839 0.926064 1.47981 1.0051 1.37062 1.39328 1.12393 1.06683 1.26353 1.12831 1.1649 1.0773 1.09501 1.1056 1.07278 1.6182 1.30683 1.33637 1.15082 1.02826 1.06671 1.172 1.0682 1.08852 1.11134 1.06129 1.095 1.05768 1.36664 1.18775 1.08169 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 1.49204 1.071 1.57852 1.11265 2.00716 1.43035 1.24273 1.1394 1.37177 1.07738 1.18435 1.121 1.1105 1.16464 1.14608 1.90119 1.43404 1.60713 1.2143 1.05538 1.04122 1.22598 1.08841 1.18889 1.16648 1.05109 1.12047 1.08488 1.34776 1.35977 1.10338 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.35187 0.955566 1.4671 1.07358 1.2443 1.32141 1.11096 1.12737 1.16378 1.10277 1.14055 1.10322 1.1142 1.12223 1.09293 1.46628 1.30388 1.29135 1.12513 1.01843 1.08517 1.18113 1.09234 1.13897 1.12948 1.04147 1.08992 1.11028 1.34263 1.20009 1.07184 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.27793 0.926276 1.31531 1.0807 1.24401 1.33531 1.08542 1.0595 1.24226 1.08941 1.13134 1.09537 1.09551 1.14304 1.12168 1.38712 1.25247 1.2903 1.19301 1.06223 1.01081 1.13794 1.14562 1.10178 1.11603 0.999287 1.08648 1.08281 1.36235 1.24383 1.06598 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.3699 0.869793 1.5567 0.89051 1.26776 1.34755 1.10573 1.13148 1.30952 1.13806 1.21543 1.1314 1.14045 1.18104 1.13605 1.65381 1.29986 1.3433 1.20306 1.08494 1.05745 1.18206 1.18339 1.11924 1.13993 1.03057 1.13283 1.06945 1.287 1.2636 1.0836 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.37735 0.878685 1.35634 0.928362 1.25776 1.34 1.1458 1.05264 1.17371 1.06283 1.11911 1.08026 1.08922 1.16776 1.07993 1.41652 1.2544 1.21283 1.16143 1.00304 1.00259 1.13424 1.105 1.06741 1.12784 0.962177 1.06921 0.966737 1.29085 1.17894 1.06624 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.48846 1.02463 1.45852 1.09142 1.36505 1.46989 1.17911 1.244 1.24257 1.18981 1.26066 1.16391 1.22014 1.20005 1.18121 1.77715 1.33393 1.29271 1.25165 1.1103 1.12142 1.23613 1.24458 1.20298 1.15972 1.0424 1.17907 1.12651 1.4501 1.31567 1.17638 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 1.4335 0.964646 1.58619 0.993182 1.28534 1.38909 1.19205 1.1318 1.33383 1.15934 1.29083 1.12065 1.17092 1.1549 1.1235 1.80648 1.32233 1.28959 1.15423 1.0404 1.07821 1.1733 1.06889 1.14072 1.10952 1.03424 1.18356 1.10532 1.38718 1.35667 1.12965 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.45458 0.933213 1.43828 1.15497 1.6161 1.41006 1.21223 1.10616 1.20035 1.14642 1.18711 1.14982 1.18186 1.19915 1.13084 1.90056 1.2871 1.25989 1.21104 1.04989 1.06973 1.19937 1.14446 1.14615 1.21976 1.03807 1.13415 1.07851 1.33554 1.32995 1.11173 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.32371 0.945042 1.37343 0.928816 1.21856 1.27456 1.15643 1.13396 1.2554 1.11191 1.15433 1.08107 1.14888 1.12156 1.08768 1.42291 1.38328 1.45235 1.15831 1.03213 1.03179 1.19544 1.13057 1.12044 1.11294 0.976082 1.11406 1.05625 1.28856 1.27373 1.09447 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.43534 1.12889 1.37321 1.17108 1.37381 1.46302 1.18819 1.08701 1.24185 1.13421 1.16577 1.11168 1.12627 1.16472 1.15112 1.77578 1.24129 1.16332 1.19347 1.05981 1.00726 1.14073 1.06239 1.14324 1.15078 0.971297 1.13435 1.09829 1.43203 1.23924 1.12712 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.35197 1.02351 1.39368 0.980913 1.18751 1.30053 1.15728 1.06644 1.19475 1.07194 1.11459 1.05839 1.09547 1.09994 1.07158 1.40435 1.32455 1.3076 1.15302 0.991107 1.05683 1.1991 1.10225 1.1237 1.0517 0.982537 1.06332 1.0288 1.28725 1.16515 1.04485 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.43217 1.07599 1.37835 1.179 1.48883 1.40573 1.19894 1.14895 1.31636 1.15256 1.17148 1.11478 1.16238 1.14712 1.14185 1.73422 1.28286 1.25924 1.1937 1.07562 1.03814 1.18004 1.10687 1.14471 1.12933 1.04156 1.11573 1.07108 1.35179 1.33052 1.13122 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.50129 0.905433 1.60759 0.900121 1.4141 1.49206 1.23391 1.11522 1.16857 1.15698 1.22049 1.1077 1.15247 1.18193 1.1248 1.67937 1.49945 1.64912 1.2184 1.04405 1.10194 1.28816 1.10042 1.15271 1.13195 1.0583 1.12254 1.14753 1.44598 1.46272 1.1277 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 1.47863 0.939709 1.55494 0.933496 1.83219 1.44253 1.14912 1.14283 1.39955 1.1411 1.19575 1.13771 1.18607 1.14625 1.18969 1.87368 1.46713 1.5319 1.25166 1.08269 1.04921 1.22275 1.08021 1.17188 1.14884 1.00599 1.16008 1.08988 1.42402 1.3606 1.14658 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.4334 0.92288 1.35882 0.905941 1.32265 1.4064 1.1504 1.09769 1.12105 1.15011 1.17971 1.11211 1.1475 1.2052 1.13884 1.5997 1.32816 1.25583 1.23356 1.05696 1.03611 1.19625 1.04026 1.13061 1.17578 1.05172 1.12609 1.07095 1.41377 1.22732 1.13868 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.47598 0.930469 1.56114 0.995589 1.39599 1.43935 1.23866 1.14177 1.17611 1.1538 1.28265 1.11695 1.1517 1.10577 1.09936 1.69648 1.36343 1.3391 1.16586 0.99591 1.07409 1.24003 1.16833 1.16125 1.09335 1.06874 1.1739 1.11842 1.44005 1.39479 1.11285 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.366 1.13797 1.41478 1.0976 1.72044 1.35967 1.15672 1.11768 1.30371 1.13377 1.18145 1.08781 1.16077 1.13236 1.11914 1.93625 1.29437 1.29924 1.20502 1.05218 1.02443 1.23709 1.12865 1.18263 1.15845 1.00693 1.1759 1.02027 1.30946 1.317 1.13503 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.29825 0.953625 1.38711 0.984467 1.17983 1.29629 1.15263 1.07722 1.18019 1.08031 1.14226 1.06351 1.14379 1.09615 1.0829 1.45532 1.28708 1.2656 1.13166 1.01649 1.02704 1.14275 1.17425 1.09237 1.06572 1.00586 1.08067 1.0926 1.28227 1.27219 1.0597 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 1.3983 0.913465 1.32939 0.956128 1.31424 1.41078 1.12618 1.09187 1.26479 1.10944 1.11399 1.10938 1.1324 1.15619 1.15312 1.63803 1.2173 1.1902 1.19592 1.08885 1.04288 1.13574 1.19821 1.12055 1.13452 1.02057 1.09041 1.03923 1.29603 1.19817 1.10816 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.48584 1.05596 1.36123 1.08109 1.59825 1.439 1.21866 1.16518 1.35035 1.17197 1.21656 1.13743 1.17941 1.14834 1.09911 1.92928 1.3209 1.25191 1.19854 1.06547 1.08305 1.23589 1.20014 1.19108 1.1619 1.02736 1.14125 1.08826 1.35779 1.348 1.15766 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.44424 0.939123 1.55753 0.937783 1.19838 1.42674 1.16163 1.11678 1.29684 1.12518 1.12907 1.12309 1.10515 1.16829 1.15749 1.71593 1.31705 1.31767 1.17922 1.02807 1.0842 1.1888 1.14633 1.13052 1.14755 0.985516 1.14595 1.02996 1.35321 1.26884 1.12003 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.49471 1.02166 1.60616 1.02685 1.55763 1.44207 1.15819 1.13216 1.34371 1.18882 1.25714 1.12965 1.17829 1.16496 1.1212 1.89337 1.39707 1.51209 1.21127 1.06272 1.08284 1.24802 1.05523 1.21529 1.16009 1.06895 1.17999 1.09698 1.41446 1.41643 1.20131 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.45895 0.967617 1.41527 1.01721 1.23623 1.39735 1.20175 1.07878 1.26029 1.05631 1.12399 1.07111 1.09648 1.15128 1.10386 1.36301 1.32131 1.2753 1.12694 1.02083 1.05391 1.16641 1.07384 1.11515 1.10774 1.01817 1.06902 1.06353 1.40778 1.34032 1.04708 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.34325 0.892391 1.40455 0.952657 1.43004 1.33232 1.03695 1.07085 1.12019 1.07772 1.1116 1.07773 1.0857 1.12651 1.1019 1.67353 1.2857 1.30681 1.14294 1.05212 1.00241 1.11444 1.01303 1.04394 1.09426 0.95772 1.05953 1.01683 1.31237 1.11953 1.04401 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.44176 1.00484 1.36685 1.02055 1.28322 1.42355 1.15576 1.09282 1.25501 1.13549 1.14517 1.09985 1.16763 1.12705 1.11922 1.52919 1.39684 1.48566 1.18757 1.02677 1.08365 1.20969 1.0943 1.14983 1.11171 1.02903 1.11755 1.10541 1.3745 1.28041 1.11213 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.27926 0.92148 1.2242 0.941931 1.31662 1.24823 1.08037 1.01598 1.21708 1.04805 1.05857 1.07706 1.04737 1.07342 1.07135 1.73494 1.15903 1.16231 1.14055 0.972769 0.96672 1.1221 1.152 1.1076 1.06159 1.01044 1.03063 1.04244 1.21575 1.21341 1.00865 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 1.38648 0.965871 1.49666 1.00266 1.4466 1.34357 1.20279 1.13961 1.26673 1.11256 1.19003 1.08001 1.14152 1.14654 1.11504 1.69961 1.37951 1.45352 1.21325 1.04065 1.06285 1.22101 1.13813 1.12752 1.11932 1.00964 1.10495 1.0496 1.26571 1.32638 1.10407 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.3796 0.956024 1.46134 0.895183 1.24141 1.35555 1.14492 1.08742 1.33193 1.06479 1.16538 1.09761 1.10983 1.12096 1.1232 1.40006 1.32837 1.38302 1.17414 1.04349 1.01378 1.1953 1.14441 1.11823 1.09876 1.01679 1.07274 1.09149 1.29904 1.25351 1.03043 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 1.35162 0.88771 1.35495 0.930653 1.27429 1.3562 1.23141 1.07726 1.18891 1.06843 1.13643 1.10837 1.13593 1.13716 1.14518 1.71363 1.22356 1.17035 1.20295 1.04233 1.01967 1.16316 1.14183 1.11228 1.1113 0.996568 1.08713 1.06588 1.30712 1.22795 1.04416 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.36002 0.963632 1.4683 1.06891 1.32814 1.29977 1.20603 1.09036 1.20022 1.09969 1.15563 1.08963 1.12824 1.13154 1.10179 1.64097 1.31358 1.31004 1.15579 1.00648 1.05432 1.21906 1.13894 1.16429 1.11139 1.00214 1.10661 1.05021 1.28183 1.19123 1.06228 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 1.52562 1.11814 1.54456 1.11055 2.08946 1.446 1.22396 1.0874 1.07567 1.10206 1.15231 1.09159 1.1142 1.11732 1.09448 1.99729 1.50761 1.66483 1.20536 1.03606 1.0206 1.28323 1.09577 1.31989 1.11668 0.959112 1.15517 1.101 1.43348 1.55873 1.06417 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.33159 0.964949 1.43366 0.968576 1.24812 1.29774 1.14472 1.10042 1.23528 1.04065 1.1458 1.09617 1.10511 1.13764 1.10395 1.61771 1.23261 1.16701 1.15823 1.01125 1.03692 1.12644 1.12148 1.10087 1.07117 0.976575 1.05463 1.05851 1.36036 1.19533 1.00842 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 1.61119 0.997475 1.73047 0.944934 1.82494 1.52571 1.25295 1.18791 1.31223 1.20113 1.28528 1.19196 1.20537 1.22104 1.20042 1.98792 1.55653 1.65628 1.30189 1.10259 1.08775 1.29519 1.12795 1.18675 1.1979 1.03758 1.22263 1.16775 1.46815 1.42572 1.19358 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.38392 1.05017 1.40247 1.00164 1.42978 1.35571 1.23402 1.10669 1.32217 1.08377 1.18012 1.10613 1.14806 1.1611 1.14148 1.68784 1.41335 1.50644 1.21228 1.03742 1.08764 1.22627 1.09213 1.11992 1.12776 1.04548 1.08581 1.08846 1.31933 1.29179 1.07387 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.39007 0.921827 1.47119 1.02183 1.23911 1.37589 1.1919 1.05067 1.13161 1.09374 1.19853 1.09986 1.08958 1.13387 1.08027 1.54122 1.39731 1.43361 1.15516 1.01912 1.02241 1.19826 1.06991 1.09226 1.09861 1.00781 1.08689 1.07646 1.35745 1.28829 1.05378 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.41841 0.983913 1.56694 1.02649 1.24805 1.37199 1.22066 1.09984 1.19186 1.14572 1.18498 1.14735 1.09498 1.19217 1.15023 1.3295 1.44084 1.50069 1.19479 1.06696 1.09108 1.24508 1.20005 1.11918 1.16976 0.984022 1.17376 1.16846 1.35542 1.30076 1.14173 NA



Figures









post

Positive Correlations (FDR = )



Negative Correlations (FDR = )
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11 V12 V13 V14
Tract Name Cerebellum_R Cerebellum_L Fornix_L Corpus_Callosum_Tapetum Corpus_Callosum_Forceps_Major Corticostriatal_Tract_Posterior_R Thalamic_Radiation_Superior_L Fornix_R Corpus_Callosum_Body Inferior_Longitudinal_Fasciculus_R Cingulum_Parolfactory_R Middle_Cerebellar_Peduncle NA
number of tracts 98 41 37 33 27 18 16 16 15 14 11 10 NA
mean length(mm) 55.8163 53.6585 57.4054 56.1818 60 54.5556 60.625 58.625 58.2667 53.8571 54.5455 53.8 NA
span(mm) 25.8391 24.0734 22.6851 22.7555 23.7668 25.7988 18.2805 24.6133 19.6649 24.7899 25.3908 19.9317 NA
curl 2.16015 2.22895 2.53053 2.46893 2.52453 2.11465 3.31637 2.38184 2.96299 2.17254 2.14824 2.69922 NA
elongation 6.68186 9.03333 12.0103 9.99556 11.5395 12.3436 19.8981 18.9002 13.4722 13.6036 18.8424 16.4131 NA
diameter(mm) 8.35342 5.94006 4.77966 5.62068 5.19953 4.41976 3.04677 3.10181 4.32496 3.95904 2.89483 3.27787 NA
volume(mm^3) 3059 1487 1030 1394 1274 837 442 443 856 663 359 454 NA
trunk volume(mm^3) 370 73 0 0 0 0 0 0 104 64 0 0 NA
branch volume(mm^3) 2689 1414 1030 1394 1274 837 442 443 752 599 359 454 NA
total surface area(mm^2) 16740 10844 6581 9438 9489 6793 2914 2829 7243 5035 2381 3951 NA
total radius of end regions(mm) 13.3287 15.5333 14.6988 31.1558 26.7597 26.5599 13.6556 11.2261 39.2338 29.5107 8.31607 24.8112 NA
total area of end regions(mm^2) 136 55 51 53 46 30 19 26 28 26 15 16 NA
irregularity 11.4283 10.8295 7.6347 9.51362 9.68178 8.96756 5.02166 4.95205 9.14885 7.51651 4.79985 7.13154 NA
area of end region 1(mm^2) 64 27 24 26 23 14 12 10 14 13 8 8 NA
radius of end region 1(mm) 4.9644 6.80287 7.40334 14.483 16.8972 16.7997 9.35098 5.40002 23.6172 14.5655 3.50596 15.2182 NA
irregularity of end region 1 1.20977 5.38482 7.17454 25.3451 38.9988 63.3324 22.8919 9.16095 125.164 51.2694 4.82696 90.9467 NA
area of end region 2(mm^2) 72 28 27 27 23 16 7 16 14 13 7 8 NA
radius of end region 2(mm) 8.36426 8.73039 7.29542 16.6728 9.86254 9.76018 4.30458 5.82612 15.6166 14.9452 4.81011 9.59295 NA
irregularity of end region 2 3.05262 8.55183 6.19279 32.3446 13.2862 18.7045 8.31597 6.66483 54.7264 53.9773 10.3839 36.138 NA
qa 0.113174 0.120835 0.159667 0.318856 0.300627 0.238796 0.178114 0.15409 0.296767 0.208152 0.1926 0.194998 NA
nqa 0.173883 0.185653 0.245314 0.489894 0.461887 0.366889 0.273656 0.236746 0.455956 0.319808 0.295913 0.299598 NA
gfa 0.0376294 0.0407121 0.0901919 0.139571 0.116978 0.102399 0.086559 0.0900583 0.127785 0.0873681 0.089707 0.095305 NA
iso 0.689552 0.704765 0.380438 0.44225 0.541735 0.503395 0.425501 0.357178 0.46085 0.512676 0.488861 0.428733 NA
dec_t 0.406912 0.466407 1.10486 0.820284 0.603644 0.449951 0.918052 0.515722 0.973608 0.369261 0.992257 0.755513 NA
inc_t 0.365001 0.482648 0.27851 0.38128 0.348741 0.630374 0.166284 0.477125 0.256754 0.836844 0.272859 0.50363 NA
ICBM152_adult.T1W 175.044 169.621 170.208 209.644 195.9 220.918 184.413 157.984 207.014 228.829 181.023 207.479 NA
ICBM152_adult.WM 47.7014 34.6553 64.3642 213.99 181.192 238.401 114.675 50.555 212.531 245.12 97.3368 207.031 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.21766 1.02641 1.40593 1.35837 1.45683 1.15948 1.10783 1.58928 1.326 1.08982 1.11262 1.30463 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 1.03041 1.01215 2.17826 1.52647 1.69664 1.10509 1.91302 2.17783 1.44132 1.07543 1.11757 1.24058 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.02337 0.933305 1.63191 1.35837 1.42632 1.09685 1.26617 1.69167 1.28809 1.10725 1.05394 1.32473 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 0.979925 0.836262 1.42284 1.27706 1.3151 1.10715 1.15231 1.46936 1.30089 1.09897 1.10602 1.29745 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 0.970989 0.918416 1.77239 1.32678 1.52274 1.14564 1.45164 1.79575 1.32479 1.06039 1.16096 1.23419 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.00485 0.941159 1.63238 1.30344 1.39549 1.09144 1.34348 1.7866 1.29438 1.08041 1.10572 1.28959 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 1.09789 1.08231 2.06672 1.42602 1.57495 1.11149 1.94602 2.09523 1.40872 1.08493 1.15532 1.31884 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.00373 0.958328 1.48481 1.28233 1.37915 1.11322 1.18341 1.57538 1.27022 1.10872 1.08931 1.13892 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.01688 1.0381 1.43706 1.23715 1.33536 1.08305 1.16637 1.53177 1.2255 1.08035 1.10515 1.22363 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 0.933603 0.887459 1.44383 1.3348 1.47355 1.12483 1.22695 1.83892 1.30421 1.11309 1.16187 1.28041 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 0.902834 0.93247 1.38389 1.30191 1.32435 1.06034 1.2788 1.49569 1.29075 1.06498 1.05777 1.2482 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.03727 1.02226 1.59545 1.44786 1.49034 1.18759 1.42021 1.92547 1.39642 1.20389 1.2635 1.35195 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 0.964616 0.96036 1.57573 1.39755 1.5239 1.13718 1.17253 2.00204 1.33292 1.21626 1.08079 1.29048 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.07739 1.12291 1.89342 1.40229 1.48332 1.1331 1.63613 2.14915 1.39819 1.09281 1.21307 1.28964 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.01386 0.94436 1.48807 1.28405 1.45132 1.0945 1.1906 1.5933 1.24716 1.12093 1.1821 1.23779 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.32548 1.0891 1.65551 1.38249 1.34291 1.15871 1.3349 1.9317 1.3729 1.14227 1.02582 1.22815 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.13903 0.97032 1.36711 1.26983 1.41579 1.04962 1.05943 1.48175 1.24024 1.08843 1.14981 1.24324 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.16579 1.16132 1.66364 1.36493 1.33845 1.1784 1.52177 1.88642 1.32846 1.09752 1.11154 1.29815 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 0.865776 0.869475 1.63977 1.41098 1.62201 1.14509 1.54476 1.78842 1.36169 1.05469 1.02719 1.24412 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 0.962107 0.931354 2.04415 1.40589 1.59363 1.16422 1.7357 2.05796 1.39759 1.09202 1.17523 1.34307 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.0227 0.909397 1.63401 1.37038 1.34744 1.13372 1.31712 1.72779 1.33032 1.11107 1.00724 1.13388 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.01296 0.916874 1.65306 1.38866 1.45672 1.16449 1.3619 1.90112 1.3581 1.07804 1.13434 1.27296 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.13156 1.074 1.88973 1.32258 1.38791 1.13334 1.66515 2.14947 1.33533 1.08734 1.11711 1.25611 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.02243 0.960027 1.35705 1.22616 1.33821 1.08514 1.08601 1.59859 1.22856 1.07671 1.12516 1.17357 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 0.907896 0.947057 1.57987 1.3794 1.33275 1.1005 1.28097 1.78461 1.36712 1.07241 1.16256 1.24093 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.06383 1.0058 1.86502 1.42562 1.37061 1.16772 1.61011 2.11908 1.3919 1.09329 1.21118 1.30927 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.02692 0.913313 1.36814 1.41523 1.43153 1.14858 1.16735 1.86163 1.34048 1.07943 1.15955 1.33654 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.00402 0.981082 1.67956 1.41054 1.59686 1.17728 1.50255 2.12754 1.37251 1.04918 1.06677 1.31158 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 0.959817 1.00183 1.4017 1.37104 1.46425 1.05092 1.14222 1.51044 1.31673 1.09734 1.06182 1.29142 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 0.966128 0.875397 1.67142 1.28672 1.42704 1.06779 1.34678 1.78812 1.2944 1.03275 1.123 1.22631 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 0.994489 0.99054 1.55741 1.41136 1.40364 1.12164 1.20849 1.69002 1.33257 1.09353 1.1574 1.29399 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 0.971401 0.898289 1.58875 1.23746 1.297 1.06048 1.2032 1.99739 1.23857 1.02667 1.14651 1.22234 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 0.995627 1.0216 1.6462 1.3305 1.42282 1.11691 1.45959 1.84973 1.33871 1.10602 1.10372 1.22375 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 0.980662 0.882924 1.45451 1.31694 1.48433 1.03927 1.23696 1.552 1.27266 1.06265 1.07326 1.23865 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 0.83991 0.883353 1.40632 1.27807 1.29813 1.04708 1.2069 1.84344 1.26252 1.05123 1.10043 1.16497 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.02388 0.991653 1.54182 1.32455 1.37258 1.09821 1.22728 1.82003 1.27324 1.14448 1.13778 1.21425 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 1.14487 1.11146 2.1624 1.42705 1.64408 1.09806 1.983 2.18901 1.39471 1.06082 1.0809 1.11741 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.00376 0.972487 1.54691 1.28517 1.34864 1.03346 1.18731 1.8203 1.22009 1.13221 1.13222 1.25269 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 0.916655 0.904298 1.97237 1.50048 1.64698 1.18352 1.85205 2.13887 1.42715 1.13223 1.10428 1.29883 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.14588 1.0487 1.68247 1.32728 1.39955 1.09233 1.39676 1.8518 1.29425 1.18848 1.09116 1.35253 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 0.997525 0.960113 1.42683 1.29269 1.38908 1.0712 1.13751 1.63334 1.30911 1.01407 1.0561 1.20636 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.09767 0.971008 1.39593 1.3457 1.44311 1.1599 1.2306 1.46948 1.28781 1.0794 1.13037 1.23391 NA



Figures









Peri and Post

Positive Correlations (FDR = )



Negative Correlations (FDR = )
V1 V2 V3 V4 V5 V6 V7 V8 V9 V10 V11 V12 V13 V14 V15 V16 V17 V18 V19 V20
Tract Name Corpus_Callosum_Tapetum Fornix_L Cerebellum_R Corpus_Callosum_Forceps_Major Corpus_Callosum_Body Thalamic_Radiation_Superior_L Cingulum_Frontal_Parietal_L Inferior_Fronto_Occipital_Fasciculus_L Cerebellum_L Optic_Radiation_L Thalamic_Radiation_Anterior_L Inferior_Longitudinal_Fasciculus_L Cingulum_Parolfactory_R Anterior_Commissure Thalamic_Radiation_Superior_R Arcuate_Fasciculus_L Cingulum_Frontal_Parahippocampal_L Thalamic_Radiation_Posterior_L NA
number of tracts 1226 501 364 360 300 241 128 87 64 60 33 32 30 25 19 13 11 10 NA
mean length(mm) 59.8887 55.0228 54.9099 56.2382 55.0351 57.0684 59.4798 54.2143 52.257 53.641 53.0334 56.7611 54.6772 58.5027 56.6408 67.5389 62.0182 58.6093 NA
span(mm) 23.0349 21.2746 25.8355 22.3947 21.2982 18.0732 25.7073 25.5539 24.3949 25.7384 24.2716 27.144 25.8375 28.0447 17.0118 25.4128 25.7148 13.2004 NA
curl 2.59991 2.58631 2.12537 2.51122 2.58402 3.15763 2.31374 2.12157 2.14213 2.08408 2.185 2.09111 2.1162 2.08605 3.3295 2.65767 2.41177 4.43997 NA
elongation 4.51986 5.73418 6.40257 6.11981 7.29372 6.99422 12.5639 8.78939 8.89985 9.79302 15.9932 12.4207 18.0972 13.4834 16.7284 28.7862 18.6263 18.3811 NA
diameter(mm) 13.2501 9.59557 8.57623 9.18954 7.54555 8.15937 4.73417 6.16816 5.87166 5.47747 3.31599 4.56988 3.02131 4.33885 3.38591 2.34622 3.3296 3.18856 NA
volume(mm^3) 8258 3979 3172 3730 2461 2984 1047 1620 1415 1264 458 931 392 865 510 292 540 468 NA
trunk volume(mm^3) 0 2726 2721 421 1788 1079 451 423 581 716 249 343 232 365 194 241 0 134 NA
branch volume(mm^3) 8258 1253 451 3309 673 1905 596 1197 834 548 209 588 160 500 316 51 540 334 NA
total surface area(mm^2) 19137 11252 7360 12085 7326 9572 3840 5176 5810 4121 2319 4341 1538 3539 2304 1587 3985 2749 NA
total radius of end regions(mm) 32.8165 12.8825 8.57697 29.3568 12.3802 16.7987 8.69367 18.6564 8.8892 7.21893 6.30822 27.2121 6.59675 6.53955 11.4442 2.77503 16.2521 19.2262 NA
total area of end regions(mm^2) 1436 545 395 485 349 344 149 126 99 93 48 54 43 46 34 22 20 20 NA
irregularity 7.67643 6.7837 4.97486 7.4434 5.61547 6.54335 4.34078 4.92691 6.02727 4.46453 4.19748 5.32702 2.9635 4.43792 3.82409 3.18789 6.14281 4.68235 NA
area of end region 1(mm^2) 718 279 183 246 169 191 75 65 48 44 24 27 20 22 17 12 10 10 NA
radius of end region 1(mm) 16.6702 7.44576 4.00511 18.675 5.95792 8.73076 3.67558 11.3385 4.23791 2.59297 2.56697 14.3088 3.25196 2.33661 8.16864 1.54238 7.70502 14.2364 NA
irregularity of end region 1 1.21592 0.624257 0.275377 4.45383 0.659861 1.25378 0.565901 6.21364 1.17547 0.480055 0.862545 23.8226 1.66115 0.779649 12.3311 0.622804 18.6508 63.6723 NA
area of end region 2(mm^2) 718 266 212 239 180 153 74 61 51 49 24 27 23 24 17 10 10 10 NA
radius of end region 2(mm) 16.1463 5.43678 4.57187 10.6819 6.42225 8.06798 5.01809 7.31791 4.65129 4.62596 3.74125 12.9034 3.34479 4.20294 3.27556 1.23265 8.54707 4.98975 NA
irregularity of end region 2 1.1407 0.349101 0.309743 1.49985 0.719867 1.33656 1.06904 2.758 1.33268 1.37201 1.8322 19.3727 1.52813 2.3123 1.98276 0.477345 22.9501 7.82182 NA
qa 0.318543 0.146993 0.113318 0.360407 0.361364 0.16051 0.124042 0.242017 0.133094 0.240337 0.113155 0.224644 0.186514 0.238323 0.173338 0.127433 0.130165 0.203824 NA
nqa 0.489414 0.225842 0.174103 0.553733 0.555204 0.24661 0.19058 0.371837 0.204487 0.369257 0.173853 0.345146 0.286563 0.366162 0.266318 0.19579 0.199987 0.313157 NA
gfa 0.141133 0.0825864 0.0373387 0.140489 0.153211 0.0804185 0.0602649 0.110526 0.0416275 0.104687 0.0565134 0.10488 0.0856414 0.105417 0.0877095 0.0608377 0.0639821 0.0982858 NA
iso 0.432339 0.387294 0.705463 0.521769 0.445853 0.422609 0.454353 0.465633 0.735139 0.492563 0.459666 0.453794 0.507964 0.488596 0.403641 0.476158 0.446017 0.424525 NA
dec_t 1.01336 0.645181 0.836062 0.721683 1.11303 0.568983 0.550621 0.593385 0.67994 0.542209 0.528851 0.772552 0.234498 0.565625 0.228554 0.781521 0.477706 0.586243 NA
inc_t 0.075908 0.145227 0.0854902 0.0959671 0.0594916 0.0877072 0.0981668 0.136507 0.158391 0.142242 0.115801 0.0874213 0.391055 0.132117 0.435069 0.0815939 0.11439 0.0682009 NA
ICBM152_adult.T1W 197.743 174.006 184.942 194.824 205.728 183.8 195.45 191.596 153.276 181.779 197.211 191.742 156.835 181.338 167.89 201.359 190.415 191.351 NA
ICBM152_adult.WM 184.574 71.7215 74.0861 173.363 207.547 111.305 115.561 161.114 12.7161 139.79 124.421 170.131 21.7359 141.936 80.2216 146.26 105.365 138.005 NA
sub-307_space-T1w_desc-preproc_dwi mean_ad 1.56789 1.19689 1.32647 1.81263 1.44011 1.05856 1.02291 1.45974 1.09963 1.56667 0.962105 1.43825 1.09778 1.54484 1.23863 0.947486 1.02782 1.20459 NA
sub-310_space-T1w_desc-preproc_dwi mean_ad 1.73827 2.08959 0.926641 1.95965 1.5967 1.98211 2.12032 1.90857 0.957154 2.11636 2.11543 1.85626 1.13596 2.13764 2.01366 1.97939 2.06647 2.04971 NA
sub-311_space-T1w_desc-preproc_dwi mean_ad 1.53823 1.39896 1.11976 1.57346 1.37412 1.22789 1.06159 1.43638 0.998611 1.45831 0.997754 1.41543 1.02064 1.43095 1.19825 0.986904 1.09577 1.25043 NA
sub-312_space-T1w_desc-preproc_dwi mean_ad 1.38202 1.20815 0.97148 1.45568 1.37602 1.05273 1.01129 1.22629 0.844237 1.24892 0.960589 1.20742 1.08599 1.2335 1.08227 0.943479 1.01424 1.13783 NA
sub-313_space-T1w_desc-preproc_dwi mean_ad 1.50249 1.65496 1.0919 1.79992 1.39215 1.46166 1.28891 1.28228 1.06613 1.34749 1.14207 1.24674 1.22536 1.3431 1.34004 1.13037 1.3323 1.51719 NA
sub-315_space-T1w_desc-preproc_dwi mean_ad 1.44688 1.47945 0.921852 1.74203 1.41017 1.28517 1.16848 1.30444 1.05398 1.37142 1.0592 1.22896 1.15145 1.32898 1.28952 1.03111 1.18173 1.35104 NA
sub-319_space-T1w_desc-preproc_dwi mean_ad 1.60575 2.1657 0.993818 1.87126 1.46671 1.98875 1.82921 1.73629 1.26738 1.89468 1.71809 1.67846 1.21595 1.87639 1.82157 1.59589 1.88261 2.04114 NA
sub-321_space-T1w_desc-preproc_dwi mean_ad 1.42401 1.28757 0.884831 1.71954 1.26542 1.14713 1.05277 1.29412 1.0411 1.34027 1.0024 1.27651 1.08396 1.32639 1.13447 0.968238 1.08752 1.17585 NA
sub-322_space-T1w_desc-preproc_dwi mean_ad 1.32995 1.25308 0.962955 1.41717 1.29993 1.12431 1.09466 1.34511 1.06927 1.41147 1.01066 1.32271 1.06153 1.38708 1.17255 0.988028 1.11453 1.19789 NA
sub-323_space-T1w_desc-preproc_dwi mean_ad 1.4735 1.32118 0.89426 1.76541 1.33378 1.21751 1.05939 1.31556 0.906851 1.42028 1.00943 1.24861 1.12727 1.38562 1.31486 0.992284 1.08097 1.28579 NA
sub-324_space-T1w_desc-preproc_dwi mean_ad 1.46493 1.26217 0.866191 1.53489 1.35902 1.22896 1.0095 1.30094 0.91261 1.31534 0.9702 1.27428 1.01087 1.30577 1.08989 0.947425 1.05365 1.26391 NA
sub-325_space-T1w_desc-preproc_dwi mean_ad 1.58267 1.44784 0.966302 1.63648 1.51056 1.45113 1.4238 1.34106 1.14034 1.36862 1.26867 1.32936 1.26705 1.36052 1.54428 1.23968 1.41529 1.50309 NA
sub-326_space-T1w_desc-preproc_dwi mean_ad 1.52377 1.36376 0.938709 1.75803 1.35937 1.16174 1.06542 1.38716 0.945955 1.4252 1.0117 1.40395 1.12474 1.42904 1.39751 0.979085 1.09845 1.25437 NA
sub-327_space-T1w_desc-preproc_dwi mean_ad 1.57482 1.7898 0.999274 1.56164 1.49995 1.60116 1.26202 1.35816 1.12208 1.38924 1.13399 1.35008 1.21315 1.36347 1.66606 1.11996 1.32511 1.69581 NA
sub-328_space-T1w_desc-preproc_dwi mean_ad 1.39147 1.28266 1.08039 1.59276 1.22493 1.17237 1.07364 1.44525 0.950363 1.53731 1.0149 1.40445 1.17294 1.51727 1.17476 0.982473 1.08487 1.20648 NA
sub-330_space-T1w_desc-preproc_dwi mean_ad 1.55285 1.43485 1.24983 1.42999 1.45945 1.35649 1.4019 1.26469 1.10795 1.23199 1.29336 1.25305 0.998068 1.24042 1.56483 1.22656 1.38978 1.38604 NA
sub-333_space-T1w_desc-preproc_dwi mean_ad 1.44454 1.19295 1.06089 1.54917 1.28531 1.02876 0.953206 1.3578 0.978739 1.39763 0.944662 1.30515 1.14897 1.37705 1.16231 0.938505 0.982283 1.14606 NA
sub-334_space-T1w_desc-preproc_dwi mean_ad 1.53923 1.56997 1.14769 1.45186 1.43924 1.49484 1.21329 1.34947 1.1406 1.36762 1.08153 1.33404 1.09985 1.35962 1.59711 1.03881 1.28423 1.56687 NA
sub-337_space-T1w_desc-preproc_dwi mean_ad 1.63841 1.48337 0.816787 1.89519 1.55166 1.49155 1.47539 1.76194 0.898279 1.93452 1.3001 1.66384 0.984365 1.92625 1.72258 1.26177 1.47632 1.43636 NA
sub-339_space-T1w_desc-preproc_dwi mean_ad 1.58981 1.96565 0.989448 1.82418 1.45048 1.75061 1.65092 1.57026 0.951059 1.72771 1.51517 1.47328 1.2444 1.68914 1.44567 1.39725 1.68502 1.80783 NA
sub-340_space-T1w_desc-preproc_dwi mean_ad 1.52229 1.43969 0.986906 1.46863 1.39254 1.28223 1.22483 1.32975 0.920062 1.33942 1.10293 1.27172 0.982385 1.31943 1.23029 1.06419 1.23063 1.33662 NA
sub-345_space-T1w_desc-preproc_dwi mean_ad 1.59672 1.46633 0.989823 1.67226 1.46399 1.34755 1.24209 1.47975 1.00646 1.51057 1.14151 1.46439 1.13125 1.49572 1.4078 1.08235 1.28619 1.36252 NA
sub-346_space-T1w_desc-preproc_dwi mean_ad 1.44816 1.81448 1.056 1.53157 1.37261 1.65951 1.32538 1.30934 1.05435 1.38927 1.1935 1.28268 1.09864 1.3552 1.70765 1.13487 1.39231 1.7479 NA
sub-348_space-T1w_desc-preproc_dwi mean_ad 1.35764 1.19604 0.933978 1.48428 1.28074 1.07622 1.07367 1.35678 1.13271 1.37841 1.08161 1.32902 1.07904 1.35967 1.16496 1.04256 1.08185 1.14016 NA
sub-350_space-T1w_desc-preproc_dwi mean_ad 1.51679 1.37247 0.894826 1.42587 1.43334 1.26213 1.20275 1.23941 0.9942 1.27313 1.06863 1.18317 1.12117 1.23273 1.3826 1.04289 1.17542 1.32989 NA
sub-351_space-T1w_desc-preproc_dwi mean_ad 1.62748 1.72305 1.01298 1.44548 1.47596 1.58791 1.39839 1.34304 1.01934 1.37388 1.28139 1.33397 1.19832 1.35931 1.74163 1.2252 1.4398 1.53763 NA
sub-353_space-T1w_desc-preproc_dwi mean_ad 1.55486 1.19892 0.959822 1.82442 1.45061 1.15413 1.13954 1.34124 0.96307 1.42454 1.07153 1.32262 1.13817 1.41516 1.58849 1.05123 1.14884 1.21667 NA
sub-354_space-T1w_desc-preproc_dwi mean_ad 1.57316 1.64046 1.02778 1.78625 1.48559 1.54577 1.46077 1.61769 1.02277 1.75985 1.29021 1.56778 1.08252 1.72063 1.77243 1.26055 1.4899 1.55799 NA
sub-355_space-T1w_desc-preproc_dwi mean_ad 1.57641 1.23127 1.01864 1.63535 1.3937 1.13599 1.0676 1.42584 1.0347 1.44041 1.00346 1.40814 1.06542 1.43597 1.28493 0.986932 1.09365 1.23905 NA
sub-356_space-T1w_desc-preproc_dwi mean_ad 1.43076 1.48506 0.981764 1.60832 1.28882 1.31457 1.23695 1.28636 0.984542 1.39485 1.11407 1.18512 1.2158 1.33606 1.41587 1.06247 1.24844 1.31816 NA
sub-357_space-T1w_desc-preproc_dwi mean_ad 1.52901 1.37607 0.951675 1.51257 1.46231 1.20876 1.12393 1.55051 1.05672 1.66865 1.09186 1.45104 1.1578 1.63417 1.26249 1.0612 1.16711 1.30383 NA
sub-358_space-T1w_desc-preproc_dwi mean_ad 1.35311 1.39777 0.933466 1.29175 1.24959 1.2292 1.06545 1.19575 0.910058 1.2062 1.04399 1.15718 1.1311 1.19402 1.37094 0.994882 1.11973 1.29419 NA
sub-359_space-T1w_desc-preproc_dwi mean_ad 1.49748 1.53672 1.03472 1.67024 1.36407 1.42523 1.10731 1.46507 0.98017 1.58149 1.03547 1.43031 1.07433 1.54886 1.37468 1.0288 1.17145 1.47713 NA
sub-360_space-T1w_desc-preproc_dwi mean_ad 1.50138 1.28117 1.08664 1.65976 1.35984 1.19102 0.99944 1.42967 0.925273 1.49529 0.946557 1.36966 1.0313 1.46507 1.32302 0.931928 1.0348 1.22337 NA
sub-362_space-T1w_desc-preproc_dwi mean_ad 1.42674 1.27209 0.806613 1.39706 1.36002 1.16704 0.965964 1.23717 0.976385 1.23235 0.935421 1.24265 1.03626 1.2207 1.47819 0.935056 1.0152 1.2631 NA
sub-363_space-T1w_desc-preproc_dwi mean_ad 1.46342 1.39394 0.911383 1.67188 1.31869 1.24591 1.05116 1.31323 1.05129 1.34548 1.01277 1.26275 1.10583 1.33145 1.46933 0.995762 1.11273 1.27785 NA
sub-364_space-T1w_desc-preproc_dwi mean_ad 1.63882 2.17029 1.11457 1.81191 1.47647 2.06871 2.12686 1.7924 1.05759 1.96274 2.11508 1.72712 1.01281 1.92879 1.98656 1.94905 2.09418 2.15937 NA
sub-366_space-T1w_desc-preproc_dwi mean_ad 1.40771 1.33228 1.12699 1.53805 1.25902 1.14222 1.05531 1.22449 1.00297 1.19624 0.981936 1.20549 1.16056 1.19237 1.21716 0.960273 1.073 1.19338 NA
sub-368_space-T1w_desc-preproc_dwi mean_ad 1.77712 1.987 1.01518 1.96405 1.57897 1.88734 1.91195 1.74253 0.92506 1.93154 1.85072 1.64739 1.10358 1.87566 1.92912 1.71282 1.90777 1.87031 NA
sub-369_space-T1w_desc-preproc_dwi mean_ad 1.47017 1.48923 1.13878 1.54008 1.32973 1.36428 1.20863 1.5185 1.01975 1.59653 1.06921 1.41836 1.08066 1.56351 1.45653 1.04684 1.24286 1.37952 NA
sub-373_space-T1w_desc-preproc_dwi mean_ad 1.51542 1.29734 1.05688 1.6369 1.38337 1.10207 1.03925 1.52221 1.03879 1.60164 1.01395 1.4733 1.03061 1.58978 1.23908 1.00277 1.05799 1.19416 NA
sub-376_space-T1w_desc-preproc_dwi mean_ad 1.51307 1.25665 1.10052 1.77865 1.41183 1.22782 1.17314 1.59019 1.04563 1.71003 1.08079 1.52985 1.06249 1.67583 1.28368 1.04724 1.20013 1.30478 NA



Figures













RD

All subjects

Positive Correlations (FDR = )

Not significant



Negative Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_R 423 55.8203 6.19769 1684
Fornix_L 183 55.7705 5.20569 1187
Corpus_Callosum_Body 18 50.3333 3.91205 605
Cingulum_Frontal_Parietal_L 10 56.8 1.92319 165



Figures









Men

Positive Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 3786 59.0951 11.996 6679
Fornix_R 656 55.1037 9.35803 3790
Thalamic_Radiation_Superior_L 433 56.8037 8.59137 3293
Corpus_Callosum_Forceps_Major 254 59.1732 6.93631 2236
Corpus_Callosum_Tapetum 47 55.4894 5.03992 1107
Cerebellum_L 45 51.9556 3.77335 581
Thalamic_Radiation_Posterior_L 44 54.8182 4.9759 1066
Cingulum_Frontal_Parietal_L 33 61.3333 4.06247 795
Thalamic_Radiation_Superior_R 20 55 3.2024 443
Cingulum_Frontal_Parahippocampal_L 15 63.8667 3.22901 523
Thalamic_Radiation_Anterior_L 14 52.1429 2.9276 351



Negative Correlations (FDR = )



Figures









Women

Positive Correlations (FDR = )



Negative Correlations (FDR = )
.
Cerebellum_R
19
54.1065
3.50482
522



Figures









pre

Positive Correlations (FDR = )



Negative Correlations (FDR = )
.
Cerebellum_R
19
54.1065
3.50482
522



Figures









peri

Positive Correlations (FDR = )



Negative Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Corpus_Callosum_Body 114 59.7895 9.42234 4169
Corpus_Callosum_Forceps_Major 109 59.8899 9.22049 3999
Corpus_Callosum_Tapetum 89 61.3483 8.1825 3226
Cerebellum_R 71 54 8.00834 2720
Fornix_L 65 62 6.00683 1757
Corpus_Callosum_Forceps_Minor 56 57.9643 7.16174 2335
Cerebellum_L 48 53.2917 6.83263 1954
Inferior_Longitudinal_Fasciculus_R 20 60.3 4.78422 1084
Corticostriatal_Tract_Posterior_R 20 53.3 4.69307 922
Thalamic_Radiation_Posterior_R 18 54.7778 4.45013 852
Fornix_R 17 56.4706 3.07363 419
Arcuate_Fasciculus_R 16 55.5 4.18654 764
Dentatorubrothalamic_Tract_L 14 56.8571 3.73514 623
Middle_Cerebellar_Peduncle 14 61.1429 3.71288 662
Reticular_Tract_R 12 56.1667 3.02626 404
Dentatorubrothalamic_Tract_R 11 53.0909 3.88392 629
Cingulum_Frontal_Parietal_L 10 58.8 3.29042 500
Cingulum_Parolfactory_R 10 65.4 2.16158 240
Corticospinal_Tract_L 10 57.6 2.66377 321



Figures









post

Positive Correlations (FDR = )



Negative Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Cerebellum_R 140 55.5429 10.6674 4964
Fornix_L 129 59.0078 6.64599 2047
Corpus_Callosum_Tapetum 59 61.9322 7.20204 2523
Cerebellum_L 56 56.5357 6.49822 1875
Corpus_Callosum_Body 54 56.8519 7.89051 2780
Middle_Cerebellar_Peduncle 51 58.5098 7.42288 2532
Corpus_Callosum_Forceps_Major 36 63.2222 6.52797 2116
Fornix_R 34 56.4118 3.75587 625
Corpus_Callosum_Forceps_Minor 34 55.2353 5.99281 1558
Inferior_Longitudinal_Fasciculus_R 29 58.1379 5.8768 1577
Dentatorubrothalamic_Tract_R 23 59.3913 5.3317 1326
Arcuate_Fasciculus_L 18 53.8889 4.81683 982
Corticospinal_Tract_R 18 62.5556 4.12007 834
Inferior_Fronto_Occipital_Fasciculus_R 17 57.5294 4.4556 897
Corticostriatal_Tract_Posterior_R 17 61.6471 4.67899 1060
Arcuate_Fasciculus_R 15 57.4667 4.34732 853
Superior_Longitudinal_Fasciculus2_R 14 62.8571 4.14942 850
Thalamic_Radiation_Superior_L 13 60.3077 3.61797 620
Dentatorubrothalamic_Tract_L 12 54.8333 3.80954 625
Corticospinal_Tract_L 11 55.6364 3.21621 452
Medial_Lemniscus_R 11 64 3.5766 643
Cingulum_Frontal_Parietal_R 10 61.8 3.6679 653
Frontal_Aslant_Tract_R 10 54.6 3.1221 418
Corticopontine_Tract_Parietal_R 10 59.6 3.34897 525



Figures









Peri and Post

Positive Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Middle_Cerebellar_Peduncle 318 55.1761 7.75175 2604
Cerebellum_R 295 54.0339 11.2583 5379
Inferior_Longitudinal_Fasciculus_L 234 55.6838 7.83689 2686
Cerebellum_L 217 52.9217 9.3838 3660
Corpus_Callosum_Tapetum 210 56.6476 11.019 5402
Fornix_L 209 57.3397 6.57691 1948
Corpus_Callosum_Forceps_Major 198 58.0303 10.1235 4671
Fornix_R 115 55.2348 6.54971 1861
Corpus_Callosum_Body 96 57.6667 7.64342 2646
Arcuate_Fasciculus_L 72 56.25 5.92324 1550
Thalamic_Radiation_Posterior_L 56 53.4286 5.10595 1094
Thalamic_Radiation_Superior_L 47 54.383 5.78213 1428
Optic_Radiation_L 36 55.2222 4.28674 797
Cingulum_Frontal_Parahippocampal_L 26 69.6154 4.26379 994
Vermis 26 53.7692 3.16489 423
Cingulum_Parahippocampal_Parietal_R 21 56 3.56825 560
Cingulum_Frontal_Parietal_L 19 66.2105 3.40526 603
Inferior_Fronto_Occipital_Fasciculus_L 19 52 3.93068 631
Thalamic_Radiation_Posterior_R 18 53.7778 3.76903 600
Inferior_Cerebellar_Peduncle_R 18 57 3.80163 647
Thalamic_Radiation_Anterior_L 17 54.5882 2.98886 383
Corticostriatal_Tract_Anterior_R 13 53.3846 2.51403 265
Cingulum_Frontal_Parietal_R 11 58.1818 3.18998 465



Negative Correlations (FDR = )
Tract Name number of tracts mean length(mm) diameter(mm) volume(mm^3)
Fornix_L 877 56.2144 9.69517 4150
Corpus_Callosum_Tapetum 632 57.5063 9.48113 4060
Cerebellum_R 244 55.0574 8.05978 2809
Thalamic_Radiation_Superior_L 146 58.0137 6.24502 1777
Corpus_Callosum_Forceps_Major 112 54.1786 6.20627 1639
Fornix_R 66 52.1818 5.50055 1240
Cingulum_Frontal_Parietal_L 60 59.3333 5.18332 1252
Corpus_Callosum_Forceps_Minor 54 55.037 5.05602 1105
Corpus_Callosum_Body 54 55.3333 5.53415 1331
Cerebellum_L 37 52.3243 5.92771 1444
Thalamic_Radiation_Anterior_L 19 54 3.06722 399
Cingulum_Frontal_Parietal_R 15 55.8667 3.27634 471
Uncinate_Fasciculus_R 15 53.2 3.12102 407
Dentatorubrothalamic_Tract_R 15 56.5333 2.81562 352
Cingulum_Frontal_Parahippocampal_L 14 61.8571 3.6634 652
Cingulum_Parolfactory_R 10 54.2 2.40882 247



Figures